<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set NEFTEL_AC_2019[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>NF1_GRD_exprs.NF1_GRD_phenotype.cls<br>#GRD_versus_Ctrl.NF1_GRD_phenotype.cls<br>#GRD_versus_Ctrl_repos</td></tr><tr><td>Phenotype</td><td>NF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos</td></tr><tr><td>Upregulated in class</td><td>GRD</td></tr><tr><td>GeneSet</td><td>NEFTEL_AC_2019</td></tr><tr><td>Enrichment Score (ES)</td><td>0.5204621</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>1.7983316</td></tr><tr><td>Nominal p-value</td><td>0.004237288</td></tr><tr><td>FDR q-value</td><td>0.0027640455</td></tr><tr><td>FWER p-Value</td><td>0.01</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_NEFTEL_AC_2019' src='enplot_NEFTEL_AC_2019_110.png'><br><br><caption>Fig 1: Enrichment plot: NEFTEL_AC_2019    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=SPARCL1'>SPARCL1</a></td><td>SPARCL1</td><td>0</td><td>0.477</td><td>0.1861</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=PMP2'>PMP2</a></td><td>PMP2</td><td>15</td><td>0.222</td><td>0.2719</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=GATM'>GATM</a></td><td>GATM</td><td>24</td><td>0.183</td><td>0.3428</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=SLC1A3'>SLC1A3</a></td><td>SLC1A3</td><td>274</td><td>0.092</td><td>0.3672</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=PTPRZ1'>PTPRZ1</a></td><td>PTPRZ1</td><td>474</td><td>0.079</td><td>0.3888</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=PRCP'>PRCP</a></td><td>PRCP</td><td>526</td><td>0.077</td><td>0.4163</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=F3'>F3</a></td><td>F3</td><td>837</td><td>0.065</td><td>0.4271</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=PON2'>PON2</a></td><td>PON2</td><td>937</td><td>0.062</td><td>0.4466</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=ANXA5'>ANXA5</a></td><td>ANXA5</td><td>993</td><td>0.061</td><td>0.4677</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=MT3'>MT3</a></td><td>MT3</td><td>1020</td><td>0.060</td><td>0.4900</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=GPM6B'>GPM6B</a></td><td>GPM6B</td><td>1398</td><td>0.053</td><td>0.4930</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=PPAP2B'>PPAP2B</a></td><td>PPAP2B</td><td>1586</td><td>0.050</td><td>0.5039</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=TTYH1'>TTYH1</a></td><td>TTYH1</td><td>1643</td><td>0.049</td><td>0.5205</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=FABP7'>FABP7</a></td><td>FABP7</td><td>2611</td><td>0.038</td><td>0.4906</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=PLTP'>PLTP</a></td><td>PLTP</td><td>3416</td><td>0.032</td><td>0.4658</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=PMP22'>PMP22</a></td><td>PMP22</td><td>3640</td><td>0.031</td><td>0.4674</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=ATP1B2'>ATP1B2</a></td><td>ATP1B2</td><td>3756</td><td>0.030</td><td>0.4736</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=BCAN'>BCAN</a></td><td>BCAN</td><td>5383</td><td>0.021</td><td>0.4062</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=CLU'>CLU</a></td><td>CLU</td><td>6086</td><td>0.017</td><td>0.3804</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=PCDHGC3'>PCDHGC3</a></td><td>PCDHGC3</td><td>7328</td><td>0.012</td><td>0.3276</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=MLC1'>MLC1</a></td><td>MLC1</td><td>9469</td><td>0.004</td><td>0.2300</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=GFAP'>GFAP</a></td><td>GFAP</td><td>9508</td><td>0.004</td><td>0.2298</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=HOPX'>HOPX</a></td><td>HOPX</td><td>10030</td><td>0.002</td><td>0.2066</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=EDNRB'>EDNRB</a></td><td>EDNRB</td><td>10682</td><td>-0.000</td><td>0.1764</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=HEPN1'>HEPN1</a></td><td>HEPN1</td><td>11514</td><td>-0.003</td><td>0.1390</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=RAB31'>RAB31</a></td><td>RAB31</td><td>11737</td><td>-0.004</td><td>0.1301</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=CST3'>CST3</a></td><td>CST3</td><td>14040</td><td>-0.012</td><td>0.0281</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=AQP4'>AQP4</a></td><td>AQP4</td><td>14284</td><td>-0.013</td><td>0.0220</td><td>No</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=NDRG2'>NDRG2</a></td><td>NDRG2</td><td>15120</td><td>-0.017</td><td>-0.0103</td><td>No</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=S100B'>S100B</a></td><td>S100B</td><td>16586</td><td>-0.023</td><td>-0.0692</td><td>No</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=ATP1A2'>ATP1A2</a></td><td>ATP1A2</td><td>18103</td><td>-0.032</td><td>-0.1273</td><td>No</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=DBI'>DBI</a></td><td>DBI</td><td>18135</td><td>-0.032</td><td>-0.1163</td><td>No</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=TSPAN7'>TSPAN7</a></td><td>TSPAN7</td><td>18945</td><td>-0.038</td><td>-0.1389</td><td>No</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=S100A16'>S100A16</a></td><td>S100A16</td><td>19089</td><td>-0.039</td><td>-0.1302</td><td>No</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=AGT'>AGT</a></td><td>AGT</td><td>20709</td><td>-0.064</td><td>-0.1805</td><td>No</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=SPARC'>SPARC</a></td><td>SPARC</td><td>20960</td><td>-0.071</td><td>-0.1643</td><td>No</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=RAMP1'>RAMP1</a></td><td>RAMP1</td><td>21272</td><td>-0.088</td><td>-0.1443</td><td>No</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=HEY1'>HEY1</a></td><td>HEY1</td><td>21552</td><td>-0.172</td><td>-0.0902</td><td>No</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=METTL7B'>METTL7B</a></td><td>METTL7B</td><td>21587</td><td>-0.236</td><td>0.0004</td><td>No</td></tr><caption class='table'>Table: GSEA details <a href='NEFTEL_AC_2019.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='NEFTEL_AC_2019' src='NEFTEL_AC_2019_111.png'><br><br><caption>Fig 2: NEFTEL_AC_2019    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_112.png'><br><br><caption>Fig 3: NEFTEL_AC_2019: Random ES distribution    <br> Gene set null distribution of ES for <b>NEFTEL_AC_2019</b></caption></div><br></body></html>