<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set NEFTEL_G1.S_2019[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>NF1_GRD_exprs.NF1_GRD_phenotype.cls<br>#GRD_versus_Ctrl.NF1_GRD_phenotype.cls<br>#GRD_versus_Ctrl_repos</td></tr><tr><td>Phenotype</td><td>NF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos</td></tr><tr><td>Upregulated in class</td><td>GRD</td></tr><tr><td>GeneSet</td><td>NEFTEL_G1.S_2019</td></tr><tr><td>Enrichment Score (ES)</td><td>0.3566162</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>1.127816</td></tr><tr><td>Nominal p-value</td><td>0.28893444</td></tr><tr><td>FDR q-value</td><td>0.23388107</td></tr><tr><td>FWER p-Value</td><td>0.966</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_NEFTEL_G1.S_2019' src='enplot_NEFTEL_G1.S_2019_146.png'><br><br><caption>Fig 1: Enrichment plot: NEFTEL_G1.S_2019    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=RRM2'>RRM2</a></td><td>RRM2</td><td>63</td><td>0.143</td><td>0.1451</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=PCNA'>PCNA</a></td><td>PCNA</td><td>432</td><td>0.081</td><td>0.2118</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=MCM7'>MCM7</a></td><td>MCM7</td><td>981</td><td>0.061</td><td>0.2497</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=CENPK'>CENPK</a></td><td>CENPK</td><td>1184</td><td>0.057</td><td>0.2994</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=MCM2'>MCM2</a></td><td>MCM2</td><td>1649</td><td>0.049</td><td>0.3289</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=KIAA0101'>KIAA0101</a></td><td>KIAA0101</td><td>2165</td><td>0.043</td><td>0.3495</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=GINS2'>GINS2</a></td><td>GINS2</td><td>3229</td><td>0.033</td><td>0.3349</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=HIST1H4C'>HIST1H4C</a></td><td>HIST1H4C</td><td>3986</td><td>0.028</td><td>0.3292</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=PKMYT1'>PKMYT1</a></td><td>PKMYT1</td><td>4615</td><td>0.025</td><td>0.3256</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=MELK'>MELK</a></td><td>MELK</td><td>4775</td><td>0.024</td><td>0.3426</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=MCM4'>MCM4</a></td><td>MCM4</td><td>4980</td><td>0.023</td><td>0.3566</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=MCM3'>MCM3</a></td><td>MCM3</td><td>5551</td><td>0.020</td><td>0.3508</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=RRM1'>RRM1</a></td><td>RRM1</td><td>6350</td><td>0.016</td><td>0.3306</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=AURKB'>AURKB</a></td><td>AURKB</td><td>6928</td><td>0.014</td><td>0.3181</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=RAD51AP1'>RAD51AP1</a></td><td>RAD51AP1</td><td>7025</td><td>0.013</td><td>0.3275</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=MLF1IP'>MLF1IP</a></td><td>MLF1IP</td><td>7711</td><td>0.011</td><td>0.3069</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=CKS1B'>CKS1B</a></td><td>CKS1B</td><td>8557</td><td>0.008</td><td>0.2756</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=FEN1'>FEN1</a></td><td>FEN1</td><td>10096</td><td>0.002</td><td>0.2064</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=CDCA5'>CDCA5</a></td><td>CDCA5</td><td>11443</td><td>-0.003</td><td>0.1468</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=CENPM'>CENPM</a></td><td>CENPM</td><td>13407</td><td>-0.010</td><td>0.0659</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=DUT'>DUT</a></td><td>DUT</td><td>14100</td><td>-0.012</td><td>0.0468</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=ZWINT'>ZWINT</a></td><td>ZWINT</td><td>15079</td><td>-0.016</td><td>0.0185</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=GMNN'>GMNN</a></td><td>GMNN</td><td>16189</td><td>-0.021</td><td>-0.0108</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=TK1'>TK1</a></td><td>TK1</td><td>18246</td><td>-0.033</td><td>-0.0723</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=CCNE2'>CCNE2</a></td><td>CCNE2</td><td>19671</td><td>-0.046</td><td>-0.0911</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=RNASEH2A'>RNASEH2A</a></td><td>RNASEH2A</td><td>20019</td><td>-0.050</td><td>-0.0550</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=TMEM106C'>TMEM106C</a></td><td>TMEM106C</td><td>20103</td><td>-0.051</td><td>-0.0056</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=ASF1B'>ASF1B</a></td><td>ASF1B</td><td>20979</td><td>-0.072</td><td>0.0286</td><td>No</td></tr><caption class='table'>Table: GSEA details <a href='NEFTEL_G1.S_2019.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='NEFTEL_G1.S_2019' src='NEFTEL_G1.S_2019_147.png'><br><br><caption>Fig 2: NEFTEL_G1.S_2019    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_148.png'><br><br><caption>Fig 3: NEFTEL_G1.S_2019: Random ES distribution    <br> Gene set null distribution of ES for <b>NEFTEL_G1.S_2019</b></caption></div><br></body></html>