<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set NEFTEL_G2.M_2019[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>NF1_GRD_exprs.NF1_GRD_phenotype.cls<br>#GRD_versus_Ctrl.NF1_GRD_phenotype.cls<br>#GRD_versus_Ctrl_repos</td></tr><tr><td>Phenotype</td><td>NF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos</td></tr><tr><td>Upregulated in class</td><td>Ctrl</td></tr><tr><td>GeneSet</td><td>NEFTEL_G2.M_2019</td></tr><tr><td>Enrichment Score (ES)</td><td>-0.30618078</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>-1.0703233</td></tr><tr><td>Nominal p-value</td><td>0.33864543</td></tr><tr><td>FDR q-value</td><td>0.31979495</td></tr><tr><td>FWER p-Value</td><td>0.997</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_NEFTEL_G2.M_2019' src='enplot_NEFTEL_G2.M_2019_191.png'><br><br><caption>Fig 1: Enrichment plot: NEFTEL_G2.M_2019    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=NCAPD2'>NCAPD2</a></td><td>NCAPD2</td><td>1848</td><td>0.046</td><td>-0.0396</td><td>No</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=KIF11'>KIF11</a></td><td>KIF11</td><td>2139</td><td>0.043</td><td>-0.0102</td><td>No</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=MXD3'>MXD3</a></td><td>MXD3</td><td>3689</td><td>0.030</td><td>-0.0520</td><td>No</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=ARL6IP1'>ARL6IP1</a></td><td>ARL6IP1</td><td>3747</td><td>0.030</td><td>-0.0251</td><td>No</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=PSRC1'>PSRC1</a></td><td>PSRC1</td><td>3859</td><td>0.029</td><td>-0.0013</td><td>No</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=CCNA2'>CCNA2</a></td><td>CCNA2</td><td>4156</td><td>0.027</td><td>0.0121</td><td>No</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=TUBA1C'>TUBA1C</a></td><td>TUBA1C</td><td>4861</td><td>0.023</td><td>0.0024</td><td>No</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=KPNA2'>KPNA2</a></td><td>KPNA2</td><td>5292</td><td>0.021</td><td>0.0034</td><td>No</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=TTK'>TTK</a></td><td>TTK</td><td>5590</td><td>0.020</td><td>0.0091</td><td>No</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=GPSM2'>GPSM2</a></td><td>GPSM2</td><td>5709</td><td>0.019</td><td>0.0226</td><td>No</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=KIFC1'>KIFC1</a></td><td>KIFC1</td><td>6039</td><td>0.018</td><td>0.0248</td><td>No</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=ARHGAP11A'>ARHGAP11A</a></td><td>ARHGAP11A</td><td>6249</td><td>0.017</td><td>0.0316</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=KIF4A'>KIF4A</a></td><td>KIF4A</td><td>6889</td><td>0.014</td><td>0.0158</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=CDC25B'>CDC25B</a></td><td>CDC25B</td><td>7643</td><td>0.011</td><td>-0.0082</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=SMC4'>SMC4</a></td><td>SMC4</td><td>7951</td><td>0.010</td><td>-0.0127</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=H2AFZ'>H2AFZ</a></td><td>H2AFZ</td><td>8156</td><td>0.009</td><td>-0.0132</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=OIP5'>OIP5</a></td><td>OIP5</td><td>8775</td><td>0.007</td><td>-0.0352</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=CDCA3'>CDCA3</a></td><td>CDCA3</td><td>9660</td><td>0.004</td><td>-0.0727</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=SPAG5'>SPAG5</a></td><td>SPAG5</td><td>9723</td><td>0.003</td><td>-0.0724</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=CCNB2'>CCNB2</a></td><td>CCNB2</td><td>10012</td><td>0.002</td><td>-0.0834</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=CDCA8'>CDCA8</a></td><td>CDCA8</td><td>12489</td><td>-0.006</td><td>-0.1920</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=FOXM1'>FOXM1</a></td><td>FOXM1</td><td>12671</td><td>-0.007</td><td>-0.1934</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=CKAP2'>CKAP2</a></td><td>CKAP2</td><td>13638</td><td>-0.011</td><td>-0.2276</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=RACGAP1'>RACGAP1</a></td><td>RACGAP1</td><td>14057</td><td>-0.012</td><td>-0.2348</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=HMGB3'>HMGB3</a></td><td>HMGB3</td><td>14419</td><td>-0.014</td><td>-0.2380</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=PLK1'>PLK1</a></td><td>PLK1</td><td>14628</td><td>-0.014</td><td>-0.2332</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=ECT2'>ECT2</a></td><td>ECT2</td><td>16101</td><td>-0.021</td><td>-0.2808</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=CKAP2L'>CKAP2L</a></td><td>CKAP2L</td><td>16650</td><td>-0.023</td><td>-0.2829</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=REEP4'>REEP4</a></td><td>REEP4</td><td>16943</td><td>-0.025</td><td>-0.2716</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=AURKA'>AURKA</a></td><td>AURKA</td><td>17242</td><td>-0.027</td><td>-0.2589</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=KIF2C'>KIF2C</a></td><td>KIF2C</td><td>17250</td><td>-0.027</td><td>-0.2328</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=CENPF'>CENPF</a></td><td>CENPF</td><td>17620</td><td>-0.029</td><td>-0.2213</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=BUB1B'>BUB1B</a></td><td>BUB1B</td><td>17873</td><td>-0.030</td><td>-0.2031</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=ANP32E'>ANP32E</a></td><td>ANP32E</td><td>18050</td><td>-0.031</td><td>-0.1803</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=KIF20A'>KIF20A</a></td><td>KIF20A</td><td>18641</td><td>-0.036</td><td>-0.1723</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=TMPO'>TMPO</a></td><td>TMPO</td><td>18652</td><td>-0.036</td><td>-0.1373</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=CDC20'>CDC20</a></td><td>CDC20</td><td>18732</td><td>-0.036</td><td>-0.1049</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=BUB1'>BUB1</a></td><td>BUB1</td><td>18913</td><td>-0.038</td><td>-0.0756</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=TACC3'>TACC3</a></td><td>TACC3</td><td>19153</td><td>-0.040</td><td>-0.0468</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=CCNB1'>CCNB1</a></td><td>CCNB1</td><td>19401</td><td>-0.042</td><td>-0.0161</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=TROAP'>TROAP</a></td><td>TROAP</td><td>20004</td><td>-0.050</td><td>0.0055</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=RANGAP1'>RANGAP1</a></td><td>RANGAP1</td><td>20879</td><td>-0.069</td><td>0.0332</td><td bgcolor='#CCFFCC'>Yes</td></tr><caption class='table'>Table: GSEA details <a href='NEFTEL_G2.M_2019.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='NEFTEL_G2.M_2019' src='NEFTEL_G2.M_2019_192.png'><br><br><caption>Fig 2: NEFTEL_G2.M_2019    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_193.png'><br><br><caption>Fig 3: NEFTEL_G2.M_2019: Random ES distribution    <br> Gene set null distribution of ES for <b>NEFTEL_G2.M_2019</b></caption></div><br></body></html>