<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set NEFTEL_NPC1_2019[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>NF1_GRD_exprs.NF1_GRD_phenotype.cls<br>#GRD_versus_Ctrl.NF1_GRD_phenotype.cls<br>#GRD_versus_Ctrl_repos</td></tr><tr><td>Phenotype</td><td>NF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos</td></tr><tr><td>Upregulated in class</td><td>GRD</td></tr><tr><td>GeneSet</td><td>NEFTEL_NPC1_2019</td></tr><tr><td>Enrichment Score (ES)</td><td>0.48781687</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>1.7288727</td></tr><tr><td>Nominal p-value</td><td>0.007905139</td></tr><tr><td>FDR q-value</td><td>0.0046717934</td></tr><tr><td>FWER p-Value</td><td>0.021</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_NEFTEL_NPC1_2019' src='enplot_NEFTEL_NPC1_2019_113.png'><br><br><caption>Fig 1: Enrichment plot: NEFTEL_NPC1_2019    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=MAP2'>MAP2</a></td><td>MAP2</td><td>145</td><td>0.108</td><td>0.0576</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=SEZ6L'>SEZ6L</a></td><td>SEZ6L</td><td>228</td><td>0.096</td><td>0.1110</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=NXPH1'>NXPH1</a></td><td>NXPH1</td><td>253</td><td>0.094</td><td>0.1655</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=ABAT'>ABAT</a></td><td>ABAT</td><td>806</td><td>0.066</td><td>0.1788</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=FXYD6'>FXYD6</a></td><td>FXYD6</td><td>892</td><td>0.063</td><td>0.2123</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=GPR56'>GPR56</a></td><td>GPR56</td><td>1019</td><td>0.060</td><td>0.2422</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=TCF12'>TCF12</a></td><td>TCF12</td><td>1195</td><td>0.057</td><td>0.2677</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=STMN1'>STMN1</a></td><td>STMN1</td><td>1330</td><td>0.054</td><td>0.2935</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=MARCKSL1'>MARCKSL1</a></td><td>MARCKSL1</td><td>1500</td><td>0.051</td><td>0.3160</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=HIP1'>HIP1</a></td><td>HIP1</td><td>1537</td><td>0.051</td><td>0.3444</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=OLIG1'>OLIG1</a></td><td>OLIG1</td><td>1582</td><td>0.050</td><td>0.3722</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=TSPAN13'>TSPAN13</a></td><td>TSPAN13</td><td>1696</td><td>0.049</td><td>0.3958</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=DBN1'>DBN1</a></td><td>DBN1</td><td>1852</td><td>0.046</td><td>0.4161</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=HN1'>HN1</a></td><td>HN1</td><td>1966</td><td>0.045</td><td>0.4377</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=SCG3'>SCG3</a></td><td>SCG3</td><td>2487</td><td>0.039</td><td>0.4369</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=MYT1'>MYT1</a></td><td>MYT1</td><td>3053</td><td>0.035</td><td>0.4315</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=TNR'>TNR</a></td><td>TNR</td><td>3179</td><td>0.034</td><td>0.4457</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=TUBB3'>TUBB3</a></td><td>TUBB3</td><td>3623</td><td>0.031</td><td>0.4434</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=TUBA1A'>TUBA1A</a></td><td>TUBA1A</td><td>3634</td><td>0.031</td><td>0.4611</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=SERINC5'>SERINC5</a></td><td>SERINC5</td><td>3806</td><td>0.029</td><td>0.4706</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=GLCCI1'>GLCCI1</a></td><td>GLCCI1</td><td>4470</td><td>0.025</td><td>0.4550</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=PTPRS'>PTPRS</a></td><td>PTPRS</td><td>4634</td><td>0.024</td><td>0.4619</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=LMF1'>LMF1</a></td><td>LMF1</td><td>4686</td><td>0.024</td><td>0.4739</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=PFN2'>PFN2</a></td><td>PFN2</td><td>4694</td><td>0.024</td><td>0.4878</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=BCAN'>BCAN</a></td><td>BCAN</td><td>5383</td><td>0.021</td><td>0.4681</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=SOX11'>SOX11</a></td><td>SOX11</td><td>5768</td><td>0.019</td><td>0.4615</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=CHD7'>CHD7</a></td><td>CHD7</td><td>6015</td><td>0.018</td><td>0.4605</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=NPPA'>NPPA</a></td><td>NPPA</td><td>7771</td><td>0.011</td><td>0.3854</td><td>No</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=AMOTL2'>AMOTL2</a></td><td>AMOTL2</td><td>7900</td><td>0.010</td><td>0.3854</td><td>No</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=MLLT11'>MLLT11</a></td><td>MLLT11</td><td>8092</td><td>0.009</td><td>0.3820</td><td>No</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=BTG2'>BTG2</a></td><td>BTG2</td><td>8789</td><td>0.007</td><td>0.3536</td><td>No</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=MEST'>MEST</a></td><td>MEST</td><td>9440</td><td>0.004</td><td>0.3261</td><td>No</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=ASCL1'>ASCL1</a></td><td>ASCL1</td><td>10271</td><td>0.001</td><td>0.2883</td><td>No</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=LRRN1'>LRRN1</a></td><td>LRRN1</td><td>11449</td><td>-0.003</td><td>0.2354</td><td>No</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=BEX1'>BEX1</a></td><td>BEX1</td><td>12138</td><td>-0.005</td><td>0.2065</td><td>No</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=CD24'>CD24</a></td><td>CD24</td><td>12357</td><td>-0.006</td><td>0.1999</td><td>No</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=DCX'>DCX</a></td><td>DCX</td><td>12388</td><td>-0.006</td><td>0.2021</td><td>No</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=HES6'>HES6</a></td><td>HES6</td><td>12547</td><td>-0.007</td><td>0.1986</td><td>No</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=DLL1'>DLL1</a></td><td>DLL1</td><td>12760</td><td>-0.007</td><td>0.1932</td><td>No</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=SOX4'>SOX4</a></td><td>SOX4</td><td>13444</td><td>-0.010</td><td>0.1673</td><td>No</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=SHD'>SHD</a></td><td>SHD</td><td>14332</td><td>-0.013</td><td>0.1341</td><td>No</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=DLL3'>DLL3</a></td><td>DLL3</td><td>14605</td><td>-0.014</td><td>0.1300</td><td>No</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=NEU4'>NEU4</a></td><td>NEU4</td><td>16227</td><td>-0.022</td><td>0.0675</td><td>No</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=ELMO1'>ELMO1</a></td><td>ELMO1</td><td>17786</td><td>-0.030</td><td>0.0128</td><td>No</td></tr><tr><td class='lessen'>45</td><td><a href='https://ensembl.org/Search/Results?q=ELAVL4'>ELAVL4</a></td><td>ELAVL4</td><td>17794</td><td>-0.030</td><td>0.0300</td><td>No</td></tr><tr><td class='lessen'>46</td><td><a href='https://ensembl.org/Search/Results?q=ETV1'>ETV1</a></td><td>ETV1</td><td>18514</td><td>-0.035</td><td>0.0172</td><td>No</td></tr><tr><td class='lessen'>47</td><td><a href='https://ensembl.org/Search/Results?q=SEZ6'>SEZ6</a></td><td>SEZ6</td><td>18974</td><td>-0.038</td><td>0.0188</td><td>No</td></tr><tr><td class='lessen'>48</td><td><a href='https://ensembl.org/Search/Results?q=PCBP4'>PCBP4</a></td><td>PCBP4</td><td>20027</td><td>-0.050</td><td>-0.0002</td><td>No</td></tr><tr><td class='lessen'>49</td><td><a href='https://ensembl.org/Search/Results?q=GRIK2'>GRIK2</a></td><td>GRIK2</td><td>20588</td><td>-0.060</td><td>0.0096</td><td>No</td></tr><tr><td class='lessen'>50</td><td><a href='https://ensembl.org/Search/Results?q=TAGLN3'>TAGLN3</a></td><td>TAGLN3</td><td>20667</td><td>-0.062</td><td>0.0431</td><td>No</td></tr><caption class='table'>Table: GSEA details <a href='NEFTEL_NPC1_2019.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='NEFTEL_NPC1_2019' src='NEFTEL_NPC1_2019_114.png'><br><br><caption>Fig 2: NEFTEL_NPC1_2019    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_115.png'><br><br><caption>Fig 3: NEFTEL_NPC1_2019: Random ES distribution    <br> Gene set null distribution of ES for <b>NEFTEL_NPC1_2019</b></caption></div><br></body></html>