<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set NEFTEL_NPC2_2019[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>NF1_GRD_exprs.NF1_GRD_phenotype.cls<br>#GRD_versus_Ctrl.NF1_GRD_phenotype.cls<br>#GRD_versus_Ctrl_repos</td></tr><tr><td>Phenotype</td><td>NF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos</td></tr><tr><td>Upregulated in class</td><td>GRD</td></tr><tr><td>GeneSet</td><td>NEFTEL_NPC2_2019</td></tr><tr><td>Enrichment Score (ES)</td><td>0.45557898</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>1.6110197</td></tr><tr><td>Nominal p-value</td><td>0.01</td></tr><tr><td>FDR q-value</td><td>0.010855442</td></tr><tr><td>FWER p-Value</td><td>0.065</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_NEFTEL_NPC2_2019' src='enplot_NEFTEL_NPC2_2019_119.png'><br><br><caption>Fig 1: Enrichment plot: NEFTEL_NPC2_2019    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=MIAT'>MIAT</a></td><td>MIAT</td><td>69</td><td>0.142</td><td>0.0805</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=ENO2'>ENO2</a></td><td>ENO2</td><td>222</td><td>0.097</td><td>0.1305</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=FNBP1L'>FNBP1L</a></td><td>FNBP1L</td><td>323</td><td>0.088</td><td>0.1781</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=MAP1B'>MAP1B</a></td><td>MAP1B</td><td>366</td><td>0.084</td><td>0.2260</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=NDRG4'>NDRG4</a></td><td>NDRG4</td><td>811</td><td>0.065</td><td>0.2441</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=CEP170'>CEP170</a></td><td>CEP170</td><td>1058</td><td>0.059</td><td>0.2678</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=STMN1'>STMN1</a></td><td>STMN1</td><td>1330</td><td>0.054</td><td>0.2871</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=NFIX'>NFIX</a></td><td>NFIX</td><td>1346</td><td>0.054</td><td>0.3180</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=DPYSL3'>DPYSL3</a></td><td>DPYSL3</td><td>1354</td><td>0.053</td><td>0.3492</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=STMN4'>STMN4</a></td><td>STMN4</td><td>1560</td><td>0.050</td><td>0.3695</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=DBN1'>DBN1</a></td><td>DBN1</td><td>1852</td><td>0.046</td><td>0.3834</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=HN1'>HN1</a></td><td>HN1</td><td>1966</td><td>0.045</td><td>0.4048</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=UCHL1'>UCHL1</a></td><td>UCHL1</td><td>2126</td><td>0.043</td><td>0.4229</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=CRABP1'>CRABP1</a></td><td>CRABP1</td><td>2390</td><td>0.040</td><td>0.4345</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=BLCAP'>BLCAP</a></td><td>BLCAP</td><td>2739</td><td>0.037</td><td>0.4404</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=TUBB2A'>TUBB2A</a></td><td>TUBB2A</td><td>3428</td><td>0.032</td><td>0.4274</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=PKIA'>PKIA</a></td><td>PKIA</td><td>3546</td><td>0.031</td><td>0.4404</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=TUBB3'>TUBB3</a></td><td>TUBB3</td><td>3623</td><td>0.031</td><td>0.4550</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=DLX5'>DLX5</a></td><td>DLX5</td><td>4288</td><td>0.026</td><td>0.4398</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=TCF4'>TCF4</a></td><td>TCF4</td><td>4530</td><td>0.025</td><td>0.4435</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=NFIB'>NFIB</a></td><td>NFIB</td><td>4586</td><td>0.025</td><td>0.4556</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=KIF5C'>KIF5C</a></td><td>KIF5C</td><td>5343</td><td>0.021</td><td>0.4328</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=SOX11'>SOX11</a></td><td>SOX11</td><td>5768</td><td>0.019</td><td>0.4242</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=DPYSL5'>DPYSL5</a></td><td>DPYSL5</td><td>6521</td><td>0.015</td><td>0.3985</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=STMN2'>STMN2</a></td><td>STMN2</td><td>6893</td><td>0.014</td><td>0.3894</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=MLLT11'>MLLT11</a></td><td>MLLT11</td><td>8092</td><td>0.009</td><td>0.3393</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=SEPT3'>SEPT3</a></td><td>SEPT3</td><td>8419</td><td>0.008</td><td>0.3289</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=HMP19'>HMP19</a></td><td>HMP19</td><td>9304</td><td>0.005</td><td>0.2908</td><td>No</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=KIF5A'>KIF5A</a></td><td>KIF5A</td><td>9780</td><td>0.003</td><td>0.2706</td><td>No</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=SNAP25'>SNAP25</a></td><td>SNAP25</td><td>12165</td><td>-0.005</td><td>0.1630</td><td>No</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=CD24'>CD24</a></td><td>CD24</td><td>12357</td><td>-0.006</td><td>0.1577</td><td>No</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=DCX'>DCX</a></td><td>DCX</td><td>12388</td><td>-0.006</td><td>0.1598</td><td>No</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=SOX4'>SOX4</a></td><td>SOX4</td><td>13444</td><td>-0.010</td><td>0.1167</td><td>No</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=DYNC1I1'>DYNC1I1</a></td><td>DYNC1I1</td><td>16423</td><td>-0.022</td><td>-0.0082</td><td>No</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=DDAH2'>DDAH2</a></td><td>DDAH2</td><td>17039</td><td>-0.025</td><td>-0.0217</td><td>No</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=ELAVL4'>ELAVL4</a></td><td>ELAVL4</td><td>17794</td><td>-0.030</td><td>-0.0392</td><td>No</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=CD200'>CD200</a></td><td>CD200</td><td>18083</td><td>-0.031</td><td>-0.0340</td><td>No</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=IGFBPL1'>IGFBPL1</a></td><td>IGFBPL1</td><td>18280</td><td>-0.033</td><td>-0.0237</td><td>No</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=GNG3'>GNG3</a></td><td>GNG3</td><td>18848</td><td>-0.037</td><td>-0.0280</td><td>No</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=PAK3'>PAK3</a></td><td>PAK3</td><td>18892</td><td>-0.038</td><td>-0.0077</td><td>No</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=LBH'>LBH</a></td><td>LBH</td><td>20190</td><td>-0.053</td><td>-0.0369</td><td>No</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=RND3'>RND3</a></td><td>RND3</td><td>20239</td><td>-0.053</td><td>-0.0075</td><td>No</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=ATP1B1'>ATP1B1</a></td><td>ATP1B1</td><td>20422</td><td>-0.057</td><td>0.0175</td><td>No</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=TAGLN3'>TAGLN3</a></td><td>TAGLN3</td><td>20667</td><td>-0.062</td><td>0.0431</td><td>No</td></tr><caption class='table'>Table: GSEA details <a href='NEFTEL_NPC2_2019.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='NEFTEL_NPC2_2019' src='NEFTEL_NPC2_2019_120.png'><br><br><caption>Fig 2: NEFTEL_NPC2_2019    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_121.png'><br><br><caption>Fig 3: NEFTEL_NPC2_2019: Random ES distribution    <br> Gene set null distribution of ES for <b>NEFTEL_NPC2_2019</b></caption></div><br></body></html>