<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set NEFTEL_OPC_2019[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>NF1_GRD_exprs.NF1_GRD_phenotype.cls<br>#GRD_versus_Ctrl.NF1_GRD_phenotype.cls<br>#GRD_versus_Ctrl_repos</td></tr><tr><td>Phenotype</td><td>NF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos</td></tr><tr><td>Upregulated in class</td><td>GRD</td></tr><tr><td>GeneSet</td><td>NEFTEL_OPC_2019</td></tr><tr><td>Enrichment Score (ES)</td><td>0.6233505</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>2.2537508</td></tr><tr><td>Nominal p-value</td><td>0.0</td></tr><tr><td>FDR q-value</td><td>0.0</td></tr><tr><td>FWER p-Value</td><td>0.0</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_NEFTEL_OPC_2019' src='enplot_NEFTEL_OPC_2019_101.png'><br><br><caption>Fig 1: Enrichment plot: NEFTEL_OPC_2019    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=SCRG1'>SCRG1</a></td><td>SCRG1</td><td>1</td><td>0.360</td><td>0.1617</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=PMP2'>PMP2</a></td><td>PMP2</td><td>15</td><td>0.222</td><td>0.2607</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=TNS3'>TNS3</a></td><td>TNS3</td><td>26</td><td>0.178</td><td>0.3404</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=FABP5'>FABP5</a></td><td>FABP5</td><td>62</td><td>0.143</td><td>0.4032</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=VCAN'>VCAN</a></td><td>VCAN</td><td>147</td><td>0.108</td><td>0.4478</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=PTPRZ1'>PTPRZ1</a></td><td>PTPRZ1</td><td>474</td><td>0.079</td><td>0.4681</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=FXYD6'>FXYD6</a></td><td>FXYD6</td><td>892</td><td>0.063</td><td>0.4771</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=RNF13'>RNF13</a></td><td>RNF13</td><td>1055</td><td>0.059</td><td>0.4964</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=NLGN3'>NLGN3</a></td><td>NLGN3</td><td>1376</td><td>0.053</td><td>0.5053</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=GPM6B'>GPM6B</a></td><td>GPM6B</td><td>1398</td><td>0.053</td><td>0.5280</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=OLIG1'>OLIG1</a></td><td>OLIG1</td><td>1582</td><td>0.050</td><td>0.5421</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=TTYH1'>TTYH1</a></td><td>TTYH1</td><td>1643</td><td>0.049</td><td>0.5614</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=APOD'>APOD</a></td><td>APOD</td><td>1728</td><td>0.048</td><td>0.5791</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=CNP'>CNP</a></td><td>CNP</td><td>1822</td><td>0.047</td><td>0.5958</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=PHYHIPL'>PHYHIPL</a></td><td>PHYHIPL</td><td>1884</td><td>0.046</td><td>0.6137</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=PGRMC1'>PGRMC1</a></td><td>PGRMC1</td><td>2633</td><td>0.038</td><td>0.5962</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=CADM2'>CADM2</a></td><td>CADM2</td><td>2782</td><td>0.037</td><td>0.6060</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=TNR'>TNR</a></td><td>TNR</td><td>3179</td><td>0.034</td><td>0.6028</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=ALCAM'>ALCAM</a></td><td>ALCAM</td><td>3548</td><td>0.031</td><td>0.5997</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=PLP1'>PLP1</a></td><td>PLP1</td><td>3671</td><td>0.030</td><td>0.6077</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=SERINC5'>SERINC5</a></td><td>SERINC5</td><td>3806</td><td>0.029</td><td>0.6146</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=EPB41L2'>EPB41L2</a></td><td>EPB41L2</td><td>3898</td><td>0.029</td><td>0.6234</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=LMF1'>LMF1</a></td><td>LMF1</td><td>4686</td><td>0.024</td><td>0.5976</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=LHFPL3'>LHFPL3</a></td><td>LHFPL3</td><td>4996</td><td>0.023</td><td>0.5934</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=THY1'>THY1</a></td><td>THY1</td><td>5296</td><td>0.021</td><td>0.5890</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=BCAN'>BCAN</a></td><td>BCAN</td><td>5383</td><td>0.021</td><td>0.5942</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=SIRT2'>SIRT2</a></td><td>SIRT2</td><td>5580</td><td>0.020</td><td>0.5940</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=OMG'>OMG</a></td><td>OMG</td><td>6713</td><td>0.015</td><td>0.5480</td><td>No</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=PCDHGC3'>PCDHGC3</a></td><td>PCDHGC3</td><td>7328</td><td>0.012</td><td>0.5250</td><td>No</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=GPR17'>GPR17</a></td><td>GPR17</td><td>7361</td><td>0.012</td><td>0.5289</td><td>No</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=RTKN'>RTKN</a></td><td>RTKN</td><td>8045</td><td>0.009</td><td>0.5015</td><td>No</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=P2RX7'>P2RX7</a></td><td>P2RX7</td><td>8606</td><td>0.007</td><td>0.4788</td><td>No</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=SCD5'>SCD5</a></td><td>SCD5</td><td>10206</td><td>0.002</td><td>0.4053</td><td>No</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=NKAIN4'>NKAIN4</a></td><td>NKAIN4</td><td>10550</td><td>0.000</td><td>0.3896</td><td>No</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=HRASLS'>HRASLS</a></td><td>HRASLS</td><td>10626</td><td>0.000</td><td>0.3862</td><td>No</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=BCAS1'>BCAS1</a></td><td>BCAS1</td><td>10662</td><td>0.000</td><td>0.3845</td><td>No</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=LIMA1'>LIMA1</a></td><td>LIMA1</td><td>11174</td><td>-0.002</td><td>0.3616</td><td>No</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=RAB31'>RAB31</a></td><td>RAB31</td><td>11737</td><td>-0.004</td><td>0.3372</td><td>No</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=FGF12'>FGF12</a></td><td>FGF12</td><td>12435</td><td>-0.006</td><td>0.3077</td><td>No</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=CA10'>CA10</a></td><td>CA10</td><td>13883</td><td>-0.012</td><td>0.2457</td><td>No</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=LPPR1'>LPPR1</a></td><td>LPPR1</td><td>14239</td><td>-0.013</td><td>0.2351</td><td>No</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=PSAT1'>PSAT1</a></td><td>PSAT1</td><td>14297</td><td>-0.013</td><td>0.2384</td><td>No</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=FIBIN'>FIBIN</a></td><td>FIBIN</td><td>15681</td><td>-0.019</td><td>0.1827</td><td>No</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=NEU4'>NEU4</a></td><td>NEU4</td><td>16227</td><td>-0.022</td><td>0.1671</td><td>No</td></tr><tr><td class='lessen'>45</td><td><a href='https://ensembl.org/Search/Results?q=CNTN1'>CNTN1</a></td><td>CNTN1</td><td>17931</td><td>-0.031</td><td>0.1017</td><td>No</td></tr><tr><td class='lessen'>46</td><td><a href='https://ensembl.org/Search/Results?q=DBI'>DBI</a></td><td>DBI</td><td>18135</td><td>-0.032</td><td>0.1066</td><td>No</td></tr><tr><td class='lessen'>47</td><td><a href='https://ensembl.org/Search/Results?q=PLLP'>PLLP</a></td><td>PLLP</td><td>18644</td><td>-0.036</td><td>0.0990</td><td>No</td></tr><tr><td class='lessen'>48</td><td><a href='https://ensembl.org/Search/Results?q=TMEM206'>TMEM206</a></td><td>TMEM206</td><td>19314</td><td>-0.042</td><td>0.0866</td><td>No</td></tr><tr><td class='lessen'>49</td><td><a href='https://ensembl.org/Search/Results?q=GPR37L1'>GPR37L1</a></td><td>GPR37L1</td><td>19426</td><td>-0.043</td><td>0.1007</td><td>No</td></tr><caption class='table'>Table: GSEA details <a href='NEFTEL_OPC_2019.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='NEFTEL_OPC_2019' src='NEFTEL_OPC_2019_102.png'><br><br><caption>Fig 2: NEFTEL_OPC_2019    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_103.png'><br><br><caption>Fig 3: NEFTEL_OPC_2019: Random ES distribution    <br> Gene set null distribution of ES for <b>NEFTEL_OPC_2019</b></caption></div><br></body></html>