<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set NEFTEL_AC_2019[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>shNF1_exprs.shNF1_phenotype.cls<br>#shNF1_versus_shCtrl.shNF1_phenotype.cls<br>#shNF1_versus_shCtrl_repos</td></tr><tr><td>Phenotype</td><td>shNF1_phenotype.cls#shNF1_versus_shCtrl_repos</td></tr><tr><td>Upregulated in class</td><td>shCtrl</td></tr><tr><td>GeneSet</td><td>NEFTEL_AC_2019</td></tr><tr><td>Enrichment Score (ES)</td><td>-0.6190313</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>-2.1761847</td></tr><tr><td>Nominal p-value</td><td>0.0</td></tr><tr><td>FDR q-value</td><td>0.0</td></tr><tr><td>FWER p-Value</td><td>0.0</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_NEFTEL_AC_2019' src='enplot_NEFTEL_AC_2019_42.png'><br><br><caption>Fig 1: Enrichment plot: NEFTEL_AC_2019    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=PMP22'>PMP22</a></td><td>PMP22</td><td>706</td><td>0.056</td><td>0.0078</td><td>No</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=CLU'>CLU</a></td><td>CLU</td><td>1635</td><td>0.042</td><td>-0.0050</td><td>No</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=AGT'>AGT</a></td><td>AGT</td><td>3200</td><td>0.030</td><td>-0.0561</td><td>No</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=ATP1A2'>ATP1A2</a></td><td>ATP1A2</td><td>7066</td><td>0.012</td><td>-0.2270</td><td>No</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=ANXA5'>ANXA5</a></td><td>ANXA5</td><td>7934</td><td>0.009</td><td>-0.2609</td><td>No</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=HOPX'>HOPX</a></td><td>HOPX</td><td>9113</td><td>0.005</td><td>-0.3120</td><td>No</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=S100A16'>S100A16</a></td><td>S100A16</td><td>9336</td><td>0.004</td><td>-0.3193</td><td>No</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=PON2'>PON2</a></td><td>PON2</td><td>9929</td><td>0.002</td><td>-0.3451</td><td>No</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=GFAP'>GFAP</a></td><td>GFAP</td><td>10517</td><td>0.000</td><td>-0.3720</td><td>No</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=PCDHGC3'>PCDHGC3</a></td><td>PCDHGC3</td><td>10698</td><td>-0.000</td><td>-0.3803</td><td>No</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=GATM'>GATM</a></td><td>GATM</td><td>11519</td><td>-0.003</td><td>-0.4163</td><td>No</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=TSPAN7'>TSPAN7</a></td><td>TSPAN7</td><td>12707</td><td>-0.007</td><td>-0.4666</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=DBI'>DBI</a></td><td>DBI</td><td>13067</td><td>-0.008</td><td>-0.4776</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=SPARC'>SPARC</a></td><td>SPARC</td><td>13228</td><td>-0.008</td><td>-0.4789</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=EDNRB'>EDNRB</a></td><td>EDNRB</td><td>13669</td><td>-0.010</td><td>-0.4923</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=NDRG2'>NDRG2</a></td><td>NDRG2</td><td>13872</td><td>-0.011</td><td>-0.4940</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=FABP7'>FABP7</a></td><td>FABP7</td><td>14093</td><td>-0.011</td><td>-0.4960</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=METTL7B'>METTL7B</a></td><td>METTL7B</td><td>14209</td><td>-0.012</td><td>-0.4928</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=HEPN1'>HEPN1</a></td><td>HEPN1</td><td>15503</td><td>-0.017</td><td>-0.5407</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=RAB31'>RAB31</a></td><td>RAB31</td><td>15883</td><td>-0.018</td><td>-0.5449</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=GPM6B'>GPM6B</a></td><td>GPM6B</td><td>16474</td><td>-0.021</td><td>-0.5570</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=F3'>F3</a></td><td>F3</td><td>17464</td><td>-0.026</td><td>-0.5841</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=PPAP2B'>PPAP2B</a></td><td>PPAP2B</td><td>18150</td><td>-0.030</td><td>-0.5942</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=HEY1'>HEY1</a></td><td>HEY1</td><td>18686</td><td>-0.033</td><td>-0.5950</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=PTPRZ1'>PTPRZ1</a></td><td>PTPRZ1</td><td>18797</td><td>-0.034</td><td>-0.5755</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=SLC1A3'>SLC1A3</a></td><td>SLC1A3</td><td>19263</td><td>-0.038</td><td>-0.5699</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=SPARCL1'>SPARCL1</a></td><td>SPARCL1</td><td>19426</td><td>-0.039</td><td>-0.5495</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=PRCP'>PRCP</a></td><td>PRCP</td><td>19624</td><td>-0.040</td><td>-0.5294</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=BCAN'>BCAN</a></td><td>BCAN</td><td>20254</td><td>-0.048</td><td>-0.5243</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=CST3'>CST3</a></td><td>CST3</td><td>20462</td><td>-0.051</td><td>-0.4973</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=RAMP1'>RAMP1</a></td><td>RAMP1</td><td>20701</td><td>-0.055</td><td>-0.4684</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=ATP1B2'>ATP1B2</a></td><td>ATP1B2</td><td>20813</td><td>-0.058</td><td>-0.4320</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=MLC1'>MLC1</a></td><td>MLC1</td><td>20941</td><td>-0.061</td><td>-0.3940</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=S100B'>S100B</a></td><td>S100B</td><td>21093</td><td>-0.065</td><td>-0.3538</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=PLTP'>PLTP</a></td><td>PLTP</td><td>21208</td><td>-0.071</td><td>-0.3083</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=AQP4'>AQP4</a></td><td>AQP4</td><td>21268</td><td>-0.074</td><td>-0.2579</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=MT3'>MT3</a></td><td>MT3</td><td>21407</td><td>-0.084</td><td>-0.2036</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=TTYH1'>TTYH1</a></td><td>TTYH1</td><td>21573</td><td>-0.137</td><td>-0.1124</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=PMP2'>PMP2</a></td><td>PMP2</td><td>21584</td><td>-0.157</td><td>0.0006</td><td bgcolor='#CCFFCC'>Yes</td></tr><caption class='table'>Table: GSEA details <a href='NEFTEL_AC_2019.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='NEFTEL_AC_2019' src='NEFTEL_AC_2019_43.png'><br><br><caption>Fig 2: NEFTEL_AC_2019    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_44.png'><br><br><caption>Fig 3: NEFTEL_AC_2019: Random ES distribution    <br> Gene set null distribution of ES for <b>NEFTEL_AC_2019</b></caption></div><br></body></html>