<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set NEFTEL_G1.S_2019[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>shNF1_exprs.shNF1_phenotype.cls<br>#shNF1_versus_shCtrl.shNF1_phenotype.cls<br>#shNF1_versus_shCtrl_repos</td></tr><tr><td>Phenotype</td><td>shNF1_phenotype.cls#shNF1_versus_shCtrl_repos</td></tr><tr><td>Upregulated in class</td><td>shNF1</td></tr><tr><td>GeneSet</td><td>NEFTEL_G1.S_2019</td></tr><tr><td>Enrichment Score (ES)</td><td>0.39380807</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>1.3318803</td></tr><tr><td>Nominal p-value</td><td>0.09202454</td></tr><tr><td>FDR q-value</td><td>0.058548257</td></tr><tr><td>FWER p-Value</td><td>0.481</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_NEFTEL_G1.S_2019' src='enplot_NEFTEL_G1.S_2019_30.png'><br><br><caption>Fig 1: Enrichment plot: NEFTEL_G1.S_2019    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=RRM2'>RRM2</a></td><td>RRM2</td><td>67</td><td>0.095</td><td>0.1267</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=MCM2'>MCM2</a></td><td>MCM2</td><td>327</td><td>0.069</td><td>0.2088</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=CCNE2'>CCNE2</a></td><td>CCNE2</td><td>344</td><td>0.068</td><td>0.3009</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=RRM1'>RRM1</a></td><td>RRM1</td><td>1971</td><td>0.039</td><td>0.2784</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=PCNA'>PCNA</a></td><td>PCNA</td><td>2290</td><td>0.036</td><td>0.3128</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=MCM7'>MCM7</a></td><td>MCM7</td><td>3002</td><td>0.031</td><td>0.3220</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=GMNN'>GMNN</a></td><td>GMNN</td><td>3182</td><td>0.030</td><td>0.3543</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=MLF1IP'>MLF1IP</a></td><td>MLF1IP</td><td>3203</td><td>0.030</td><td>0.3938</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=CENPK'>CENPK</a></td><td>CENPK</td><td>4988</td><td>0.020</td><td>0.3388</td><td>No</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=RAD51AP1'>RAD51AP1</a></td><td>RAD51AP1</td><td>5628</td><td>0.017</td><td>0.3328</td><td>No</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=MELK'>MELK</a></td><td>MELK</td><td>6617</td><td>0.013</td><td>0.3053</td><td>No</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=CDCA5'>CDCA5</a></td><td>CDCA5</td><td>7456</td><td>0.010</td><td>0.2806</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=ZWINT'>ZWINT</a></td><td>ZWINT</td><td>7755</td><td>0.009</td><td>0.2796</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=AURKB'>AURKB</a></td><td>AURKB</td><td>8124</td><td>0.008</td><td>0.2737</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=MCM4'>MCM4</a></td><td>MCM4</td><td>8517</td><td>0.007</td><td>0.2648</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=KIAA0101'>KIAA0101</a></td><td>KIAA0101</td><td>8693</td><td>0.006</td><td>0.2653</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=MCM3'>MCM3</a></td><td>MCM3</td><td>8801</td><td>0.006</td><td>0.2684</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=FEN1'>FEN1</a></td><td>FEN1</td><td>9230</td><td>0.004</td><td>0.2546</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=DUT'>DUT</a></td><td>DUT</td><td>9801</td><td>0.003</td><td>0.2318</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=TK1'>TK1</a></td><td>TK1</td><td>10231</td><td>0.001</td><td>0.2136</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=CKS1B'>CKS1B</a></td><td>CKS1B</td><td>10937</td><td>-0.001</td><td>0.1822</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=ASF1B'>ASF1B</a></td><td>ASF1B</td><td>11588</td><td>-0.003</td><td>0.1561</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=PKMYT1'>PKMYT1</a></td><td>PKMYT1</td><td>13029</td><td>-0.008</td><td>0.0999</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=HIST1H4C'>HIST1H4C</a></td><td>HIST1H4C</td><td>17952</td><td>-0.029</td><td>-0.0889</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=TMEM106C'>TMEM106C</a></td><td>TMEM106C</td><td>19588</td><td>-0.040</td><td>-0.1100</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=CENPM'>CENPM</a></td><td>CENPM</td><td>20025</td><td>-0.045</td><td>-0.0692</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=RNASEH2A'>RNASEH2A</a></td><td>RNASEH2A</td><td>20066</td><td>-0.045</td><td>-0.0094</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=GINS2'>GINS2</a></td><td>GINS2</td><td>20871</td><td>-0.059</td><td>0.0336</td><td>No</td></tr><caption class='table'>Table: GSEA details <a href='NEFTEL_G1.S_2019.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='NEFTEL_G1.S_2019' src='NEFTEL_G1.S_2019_31.png'><br><br><caption>Fig 2: NEFTEL_G1.S_2019    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_32.png'><br><br><caption>Fig 3: NEFTEL_G1.S_2019: Random ES distribution    <br> Gene set null distribution of ES for <b>NEFTEL_G1.S_2019</b></caption></div><br></body></html>