<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set NEFTEL_MES1_2019[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>shNF1_exprs.shNF1_phenotype.cls<br>#shNF1_versus_shCtrl.shNF1_phenotype.cls<br>#shNF1_versus_shCtrl_repos</td></tr><tr><td>Phenotype</td><td>shNF1_phenotype.cls#shNF1_versus_shCtrl_repos</td></tr><tr><td>Upregulated in class</td><td>shNF1</td></tr><tr><td>GeneSet</td><td>NEFTEL_MES1_2019</td></tr><tr><td>Enrichment Score (ES)</td><td>0.38040766</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>1.4326468</td></tr><tr><td>Nominal p-value</td><td>0.03448276</td></tr><tr><td>FDR q-value</td><td>0.028057724</td></tr><tr><td>FWER p-Value</td><td>0.243</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_NEFTEL_MES1_2019' src='enplot_NEFTEL_MES1_2019_27.png'><br><br><caption>Fig 1: Enrichment plot: NEFTEL_MES1_2019    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=GFPT2'>GFPT2</a></td><td>GFPT2</td><td>4</td><td>0.141</td><td>0.0927</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=CD44'>CD44</a></td><td>CD44</td><td>141</td><td>0.084</td><td>0.1415</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=NAMPT'>NAMPT</a></td><td>NAMPT</td><td>426</td><td>0.065</td><td>0.1710</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=GJA1'>GJA1</a></td><td>GJA1</td><td>705</td><td>0.056</td><td>0.1951</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=SERPINE1'>SERPINE1</a></td><td>SERPINE1</td><td>725</td><td>0.056</td><td>0.2310</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=EFEMP1'>EFEMP1</a></td><td>EFEMP1</td><td>973</td><td>0.051</td><td>0.2532</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=ANXA2'>ANXA2</a></td><td>ANXA2</td><td>1146</td><td>0.048</td><td>0.2770</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=WWTR1'>WWTR1</a></td><td>WWTR1</td><td>1155</td><td>0.048</td><td>0.3083</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=ACTN1'>ACTN1</a></td><td>ACTN1</td><td>1227</td><td>0.047</td><td>0.3359</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=EMP1'>EMP1</a></td><td>EMP1</td><td>1560</td><td>0.043</td><td>0.3487</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=CLIC4'>CLIC4</a></td><td>CLIC4</td><td>2172</td><td>0.037</td><td>0.3448</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=MGST1'>MGST1</a></td><td>MGST1</td><td>2364</td><td>0.036</td><td>0.3593</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=SPP1'>SPP1</a></td><td>SPP1</td><td>2411</td><td>0.035</td><td>0.3804</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=C1R'>C1R</a></td><td>C1R</td><td>4214</td><td>0.024</td><td>0.3125</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=C8orf4'>C8orf4</a></td><td>C8orf4</td><td>4495</td><td>0.023</td><td>0.3144</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=CHI3L1'>CHI3L1</a></td><td>CHI3L1</td><td>4752</td><td>0.021</td><td>0.3166</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=TAGLN2'>TAGLN2</a></td><td>TAGLN2</td><td>4844</td><td>0.021</td><td>0.3262</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=ANXA1'>ANXA1</a></td><td>ANXA1</td><td>5293</td><td>0.019</td><td>0.3179</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=GSN'>GSN</a></td><td>GSN</td><td>6634</td><td>0.013</td><td>0.2645</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=C1S'>C1S</a></td><td>C1S</td><td>6766</td><td>0.013</td><td>0.2669</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=VIM'>VIM</a></td><td>VIM</td><td>7053</td><td>0.012</td><td>0.2614</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=SERPING1'>SERPING1</a></td><td>SERPING1</td><td>7077</td><td>0.012</td><td>0.2680</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=C3'>C3</a></td><td>C3</td><td>7114</td><td>0.012</td><td>0.2740</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=PRDX6'>PRDX6</a></td><td>PRDX6</td><td>7145</td><td>0.011</td><td>0.2802</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=PLP2'>PLP2</a></td><td>PLP2</td><td>8380</td><td>0.007</td><td>0.2277</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=MT1E'>MT1E</a></td><td>MT1E</td><td>8410</td><td>0.007</td><td>0.2311</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=S100A16'>S100A16</a></td><td>S100A16</td><td>9336</td><td>0.004</td><td>0.1910</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=TUBA1C'>TUBA1C</a></td><td>TUBA1C</td><td>10493</td><td>0.001</td><td>0.1376</td><td>No</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=MT2A'>MT2A</a></td><td>MT2A</td><td>10578</td><td>0.000</td><td>0.1339</td><td>No</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=S100A11'>S100A11</a></td><td>S100A11</td><td>10703</td><td>-0.000</td><td>0.1282</td><td>No</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=LGALS1'>LGALS1</a></td><td>LGALS1</td><td>11128</td><td>-0.001</td><td>0.1095</td><td>No</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=FN1'>FN1</a></td><td>FN1</td><td>11144</td><td>-0.002</td><td>0.1098</td><td>No</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=S100A10'>S100A10</a></td><td>S100A10</td><td>11216</td><td>-0.002</td><td>0.1077</td><td>No</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=CLIC1'>CLIC1</a></td><td>CLIC1</td><td>11509</td><td>-0.003</td><td>0.0959</td><td>No</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=CTSB'>CTSB</a></td><td>CTSB</td><td>12661</td><td>-0.007</td><td>0.0468</td><td>No</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=RCAN1'>RCAN1</a></td><td>RCAN1</td><td>12732</td><td>-0.007</td><td>0.0480</td><td>No</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=SERPINA3'>SERPINA3</a></td><td>SERPINA3</td><td>14162</td><td>-0.012</td><td>-0.0106</td><td>No</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=APOE'>APOE</a></td><td>APOE</td><td>15188</td><td>-0.016</td><td>-0.0479</td><td>No</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=TIMP1'>TIMP1</a></td><td>TIMP1</td><td>16033</td><td>-0.019</td><td>-0.0745</td><td>No</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=EMP3'>EMP3</a></td><td>EMP3</td><td>16399</td><td>-0.021</td><td>-0.0777</td><td>No</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=MGP'>MGP</a></td><td>MGP</td><td>17727</td><td>-0.028</td><td>-0.1211</td><td>No</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=TNFRSF1A'>TNFRSF1A</a></td><td>TNFRSF1A</td><td>18376</td><td>-0.031</td><td>-0.1305</td><td>No</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=IGFBP7'>IGFBP7</a></td><td>IGFBP7</td><td>18392</td><td>-0.032</td><td>-0.1104</td><td>No</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=NNMT'>NNMT</a></td><td>NNMT</td><td>18514</td><td>-0.032</td><td>-0.0948</td><td>No</td></tr><tr><td class='lessen'>45</td><td><a href='https://ensembl.org/Search/Results?q=MT1X'>MT1X</a></td><td>MT1X</td><td>19177</td><td>-0.037</td><td>-0.1012</td><td>No</td></tr><tr><td class='lessen'>46</td><td><a href='https://ensembl.org/Search/Results?q=NPC2'>NPC2</a></td><td>NPC2</td><td>20205</td><td>-0.047</td><td>-0.1179</td><td>No</td></tr><tr><td class='lessen'>47</td><td><a href='https://ensembl.org/Search/Results?q=SOD2'>SOD2</a></td><td>SOD2</td><td>20301</td><td>-0.048</td><td>-0.0905</td><td>No</td></tr><tr><td class='lessen'>48</td><td><a href='https://ensembl.org/Search/Results?q=A2M'>A2M</a></td><td>A2M</td><td>20660</td><td>-0.055</td><td>-0.0711</td><td>No</td></tr><tr><td class='lessen'>49</td><td><a href='https://ensembl.org/Search/Results?q=LGALS3'>LGALS3</a></td><td>LGALS3</td><td>21310</td><td>-0.076</td><td>-0.0513</td><td>No</td></tr><tr><td class='lessen'>50</td><td><a href='https://ensembl.org/Search/Results?q=IFITM3'>IFITM3</a></td><td>IFITM3</td><td>21498</td><td>-0.098</td><td>0.0045</td><td>No</td></tr><caption class='table'>Table: GSEA details <a href='NEFTEL_MES1_2019.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='NEFTEL_MES1_2019' src='NEFTEL_MES1_2019_28.png'><br><br><caption>Fig 2: NEFTEL_MES1_2019    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_29.png'><br><br><caption>Fig 3: NEFTEL_MES1_2019: Random ES distribution    <br> Gene set null distribution of ES for <b>NEFTEL_MES1_2019</b></caption></div><br></body></html>