<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set NEFTEL_NPC1_2019[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>shNF1_exprs.shNF1_phenotype.cls<br>#shNF1_versus_shCtrl.shNF1_phenotype.cls<br>#shNF1_versus_shCtrl_repos</td></tr><tr><td>Phenotype</td><td>shNF1_phenotype.cls#shNF1_versus_shCtrl_repos</td></tr><tr><td>Upregulated in class</td><td>shCtrl</td></tr><tr><td>GeneSet</td><td>NEFTEL_NPC1_2019</td></tr><tr><td>Enrichment Score (ES)</td><td>-0.60791695</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>-2.203602</td></tr><tr><td>Nominal p-value</td><td>0.0</td></tr><tr><td>FDR q-value</td><td>0.0</td></tr><tr><td>FWER p-Value</td><td>0.0</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_NEFTEL_NPC1_2019' src='enplot_NEFTEL_NPC1_2019_39.png'><br><br><caption>Fig 1: Enrichment plot: NEFTEL_NPC1_2019    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=DBN1'>DBN1</a></td><td>DBN1</td><td>840</td><td>0.054</td><td>-0.0111</td><td>No</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=CD24'>CD24</a></td><td>CD24</td><td>1617</td><td>0.042</td><td>-0.0251</td><td>No</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=SHD'>SHD</a></td><td>SHD</td><td>1903</td><td>0.039</td><td>-0.0179</td><td>No</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=SEZ6L'>SEZ6L</a></td><td>SEZ6L</td><td>2022</td><td>0.038</td><td>-0.0034</td><td>No</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=GRIK2'>GRIK2</a></td><td>GRIK2</td><td>2600</td><td>0.034</td><td>-0.0127</td><td>No</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=SOX11'>SOX11</a></td><td>SOX11</td><td>3515</td><td>0.028</td><td>-0.0407</td><td>No</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=MLLT11'>MLLT11</a></td><td>MLLT11</td><td>4075</td><td>0.025</td><td>-0.0539</td><td>No</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=ETV1'>ETV1</a></td><td>ETV1</td><td>4563</td><td>0.022</td><td>-0.0649</td><td>No</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=TSPAN13'>TSPAN13</a></td><td>TSPAN13</td><td>5703</td><td>0.017</td><td>-0.1089</td><td>No</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=DCX'>DCX</a></td><td>DCX</td><td>5806</td><td>0.017</td><td>-0.1049</td><td>No</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=LMF1'>LMF1</a></td><td>LMF1</td><td>6421</td><td>0.014</td><td>-0.1261</td><td>No</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=MEST'>MEST</a></td><td>MEST</td><td>7298</td><td>0.011</td><td>-0.1611</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=SEZ6'>SEZ6</a></td><td>SEZ6</td><td>7903</td><td>0.009</td><td>-0.1845</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=NPPA'>NPPA</a></td><td>NPPA</td><td>8364</td><td>0.007</td><td>-0.2020</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=ABAT'>ABAT</a></td><td>ABAT</td><td>9125</td><td>0.005</td><td>-0.2348</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=PFN2'>PFN2</a></td><td>PFN2</td><td>9445</td><td>0.004</td><td>-0.2476</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=LRRN1'>LRRN1</a></td><td>LRRN1</td><td>9701</td><td>0.003</td><td>-0.2579</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=CHD7'>CHD7</a></td><td>CHD7</td><td>9974</td><td>0.002</td><td>-0.2694</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=STMN1'>STMN1</a></td><td>STMN1</td><td>10027</td><td>0.002</td><td>-0.2708</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=TCF12'>TCF12</a></td><td>TCF12</td><td>10438</td><td>0.001</td><td>-0.2895</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=ELMO1'>ELMO1</a></td><td>ELMO1</td><td>10501</td><td>0.000</td><td>-0.2921</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=GLCCI1'>GLCCI1</a></td><td>GLCCI1</td><td>10727</td><td>-0.000</td><td>-0.3025</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=TUBA1A'>TUBA1A</a></td><td>TUBA1A</td><td>12515</td><td>-0.006</td><td>-0.3822</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=PTPRS'>PTPRS</a></td><td>PTPRS</td><td>13164</td><td>-0.008</td><td>-0.4081</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=TUBB3'>TUBB3</a></td><td>TUBB3</td><td>13324</td><td>-0.009</td><td>-0.4109</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=SERINC5'>SERINC5</a></td><td>SERINC5</td><td>13375</td><td>-0.009</td><td>-0.4086</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=ELAVL4'>ELAVL4</a></td><td>ELAVL4</td><td>13464</td><td>-0.009</td><td>-0.4079</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=MAP2'>MAP2</a></td><td>MAP2</td><td>14012</td><td>-0.011</td><td>-0.4275</td><td>No</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=MYT1'>MYT1</a></td><td>MYT1</td><td>15328</td><td>-0.016</td><td>-0.4802</td><td>No</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=HIP1'>HIP1</a></td><td>HIP1</td><td>15693</td><td>-0.018</td><td>-0.4879</td><td>No</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=AMOTL2'>AMOTL2</a></td><td>AMOTL2</td><td>16000</td><td>-0.019</td><td>-0.4922</td><td>No</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=HN1'>HN1</a></td><td>HN1</td><td>16160</td><td>-0.020</td><td>-0.4893</td><td>No</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=MARCKSL1'>MARCKSL1</a></td><td>MARCKSL1</td><td>16590</td><td>-0.022</td><td>-0.4979</td><td>No</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=PCBP4'>PCBP4</a></td><td>PCBP4</td><td>17000</td><td>-0.024</td><td>-0.5046</td><td>No</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=TNR'>TNR</a></td><td>TNR</td><td>18665</td><td>-0.033</td><td>-0.5645</td><td>No</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=GPR56'>GPR56</a></td><td>GPR56</td><td>19041</td><td>-0.036</td><td>-0.5634</td><td>No</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=BEX1'>BEX1</a></td><td>BEX1</td><td>20002</td><td>-0.045</td><td>-0.5847</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=BCAN'>BCAN</a></td><td>BCAN</td><td>20254</td><td>-0.048</td><td>-0.5717</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=SOX4'>SOX4</a></td><td>SOX4</td><td>20350</td><td>-0.049</td><td>-0.5506</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=BTG2'>BTG2</a></td><td>BTG2</td><td>20832</td><td>-0.058</td><td>-0.5428</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=TAGLN3'>TAGLN3</a></td><td>TAGLN3</td><td>20999</td><td>-0.063</td><td>-0.5179</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=DLL1'>DLL1</a></td><td>DLL1</td><td>21352</td><td>-0.079</td><td>-0.4932</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=FXYD6'>FXYD6</a></td><td>FXYD6</td><td>21404</td><td>-0.084</td><td>-0.4520</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=SCG3'>SCG3</a></td><td>SCG3</td><td>21484</td><td>-0.096</td><td>-0.4061</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>45</td><td><a href='https://ensembl.org/Search/Results?q=NXPH1'>NXPH1</a></td><td>NXPH1</td><td>21499</td><td>-0.099</td><td>-0.3554</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>46</td><td><a href='https://ensembl.org/Search/Results?q=DLL3'>DLL3</a></td><td>DLL3</td><td>21526</td><td>-0.105</td><td>-0.3021</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>47</td><td><a href='https://ensembl.org/Search/Results?q=OLIG1'>OLIG1</a></td><td>OLIG1</td><td>21528</td><td>-0.106</td><td>-0.2472</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>48</td><td><a href='https://ensembl.org/Search/Results?q=NEU4'>NEU4</a></td><td>NEU4</td><td>21549</td><td>-0.115</td><td>-0.1882</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>49</td><td><a href='https://ensembl.org/Search/Results?q=HES6'>HES6</a></td><td>HES6</td><td>21586</td><td>-0.160</td><td>-0.1066</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>50</td><td><a href='https://ensembl.org/Search/Results?q=ASCL1'>ASCL1</a></td><td>ASCL1</td><td>21596</td><td>-0.206</td><td>0.0000</td><td bgcolor='#CCFFCC'>Yes</td></tr><caption class='table'>Table: GSEA details <a href='NEFTEL_NPC1_2019.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='NEFTEL_NPC1_2019' src='NEFTEL_NPC1_2019_40.png'><br><br><caption>Fig 2: NEFTEL_NPC1_2019    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_41.png'><br><br><caption>Fig 3: NEFTEL_NPC1_2019: Random ES distribution    <br> Gene set null distribution of ES for <b>NEFTEL_NPC1_2019</b></caption></div><br></body></html>