<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set NEFTEL_NPC2_2019[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>shNF1_exprs.shNF1_phenotype.cls<br>#shNF1_versus_shCtrl.shNF1_phenotype.cls<br>#shNF1_versus_shCtrl_repos</td></tr><tr><td>Phenotype</td><td>shNF1_phenotype.cls#shNF1_versus_shCtrl_repos</td></tr><tr><td>Upregulated in class</td><td>shCtrl</td></tr><tr><td>GeneSet</td><td>NEFTEL_NPC2_2019</td></tr><tr><td>Enrichment Score (ES)</td><td>-0.25949636</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>-0.9178193</td></tr><tr><td>Nominal p-value</td><td>0.6044776</td></tr><tr><td>FDR q-value</td><td>0.703177</td></tr><tr><td>FWER p-Value</td><td>1.0</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_NEFTEL_NPC2_2019' src='enplot_NEFTEL_NPC2_2019_93.png'><br><br><caption>Fig 1: Enrichment plot: NEFTEL_NPC2_2019    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=NFIB'>NFIB</a></td><td>NFIB</td><td>313</td><td>0.070</td><td>0.0420</td><td>No</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=MAP1B'>MAP1B</a></td><td>MAP1B</td><td>807</td><td>0.054</td><td>0.0632</td><td>No</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=DBN1'>DBN1</a></td><td>DBN1</td><td>840</td><td>0.054</td><td>0.1053</td><td>No</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=CD24'>CD24</a></td><td>CD24</td><td>1617</td><td>0.042</td><td>0.1035</td><td>No</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=TCF4'>TCF4</a></td><td>TCF4</td><td>1950</td><td>0.039</td><td>0.1198</td><td>No</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=DYNC1I1'>DYNC1I1</a></td><td>DYNC1I1</td><td>3196</td><td>0.030</td><td>0.0861</td><td>No</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=SOX11'>SOX11</a></td><td>SOX11</td><td>3515</td><td>0.028</td><td>0.0939</td><td>No</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=PAK3'>PAK3</a></td><td>PAK3</td><td>3667</td><td>0.027</td><td>0.1086</td><td>No</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=NFIX'>NFIX</a></td><td>NFIX</td><td>4067</td><td>0.025</td><td>0.1101</td><td>No</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=MLLT11'>MLLT11</a></td><td>MLLT11</td><td>4075</td><td>0.025</td><td>0.1297</td><td>No</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=ENO2'>ENO2</a></td><td>ENO2</td><td>4590</td><td>0.022</td><td>0.1238</td><td>No</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=LBH'>LBH</a></td><td>LBH</td><td>4939</td><td>0.021</td><td>0.1243</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=DCX'>DCX</a></td><td>DCX</td><td>5806</td><td>0.017</td><td>0.0977</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=KIF5C'>KIF5C</a></td><td>KIF5C</td><td>5931</td><td>0.016</td><td>0.1050</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=ATP1B1'>ATP1B1</a></td><td>ATP1B1</td><td>7841</td><td>0.009</td><td>0.0238</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=HMP19'>HMP19</a></td><td>HMP19</td><td>8362</td><td>0.007</td><td>0.0057</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=SNAP25'>SNAP25</a></td><td>SNAP25</td><td>9191</td><td>0.005</td><td>-0.0290</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=BLCAP'>BLCAP</a></td><td>BLCAP</td><td>9800</td><td>0.003</td><td>-0.0550</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=STMN1'>STMN1</a></td><td>STMN1</td><td>10027</td><td>0.002</td><td>-0.0640</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=KIF5A'>KIF5A</a></td><td>KIF5A</td><td>12467</td><td>-0.006</td><td>-0.1723</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=STMN4'>STMN4</a></td><td>STMN4</td><td>12976</td><td>-0.008</td><td>-0.1897</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=TUBB3'>TUBB3</a></td><td>TUBB3</td><td>13324</td><td>-0.009</td><td>-0.1987</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=FNBP1L'>FNBP1L</a></td><td>FNBP1L</td><td>13350</td><td>-0.009</td><td>-0.1927</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=ELAVL4'>ELAVL4</a></td><td>ELAVL4</td><td>13464</td><td>-0.009</td><td>-0.1905</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=CEP170'>CEP170</a></td><td>CEP170</td><td>13861</td><td>-0.011</td><td>-0.2003</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=DPYSL3'>DPYSL3</a></td><td>DPYSL3</td><td>14795</td><td>-0.014</td><td>-0.2323</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=TUBB2A'>TUBB2A</a></td><td>TUBB2A</td><td>15383</td><td>-0.016</td><td>-0.2463</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=DLX5'>DLX5</a></td><td>DLX5</td><td>15548</td><td>-0.017</td><td>-0.2400</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=DDAH2'>DDAH2</a></td><td>DDAH2</td><td>15638</td><td>-0.017</td><td>-0.2300</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=NDRG4'>NDRG4</a></td><td>NDRG4</td><td>15689</td><td>-0.018</td><td>-0.2180</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=HN1'>HN1</a></td><td>HN1</td><td>16160</td><td>-0.020</td><td>-0.2237</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=DPYSL5'>DPYSL5</a></td><td>DPYSL5</td><td>16489</td><td>-0.021</td><td>-0.2217</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=CD200'>CD200</a></td><td>CD200</td><td>16725</td><td>-0.022</td><td>-0.2144</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=UCHL1'>UCHL1</a></td><td>UCHL1</td><td>16880</td><td>-0.023</td><td>-0.2028</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=STMN2'>STMN2</a></td><td>STMN2</td><td>17573</td><td>-0.027</td><td>-0.2133</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=GNG3'>GNG3</a></td><td>GNG3</td><td>17899</td><td>-0.029</td><td>-0.2052</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=CRABP1'>CRABP1</a></td><td>CRABP1</td><td>18762</td><td>-0.034</td><td>-0.2177</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=PKIA'>PKIA</a></td><td>PKIA</td><td>19374</td><td>-0.038</td><td>-0.2149</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=RND3'>RND3</a></td><td>RND3</td><td>20033</td><td>-0.045</td><td>-0.2090</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=IGFBPL1'>IGFBPL1</a></td><td>IGFBPL1</td><td>20092</td><td>-0.046</td><td>-0.1748</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=SOX4'>SOX4</a></td><td>SOX4</td><td>20350</td><td>-0.049</td><td>-0.1470</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=TAGLN3'>TAGLN3</a></td><td>TAGLN3</td><td>20999</td><td>-0.063</td><td>-0.1262</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=SEPT3'>SEPT3</a></td><td>SEPT3</td><td>21430</td><td>-0.087</td><td>-0.0758</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=MIAT'>MIAT</a></td><td>MIAT</td><td>21516</td><td>-0.103</td><td>0.0037</td><td bgcolor='#CCFFCC'>Yes</td></tr><caption class='table'>Table: GSEA details <a href='NEFTEL_NPC2_2019.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='NEFTEL_NPC2_2019' src='NEFTEL_NPC2_2019_94.png'><br><br><caption>Fig 2: NEFTEL_NPC2_2019    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_95.png'><br><br><caption>Fig 3: NEFTEL_NPC2_2019: Random ES distribution    <br> Gene set null distribution of ES for <b>NEFTEL_NPC2_2019</b></caption></div><br></body></html>