<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set NEFTEL_OPC_2019[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>shNF1_exprs.shNF1_phenotype.cls<br>#shNF1_versus_shCtrl.shNF1_phenotype.cls<br>#shNF1_versus_shCtrl_repos</td></tr><tr><td>Phenotype</td><td>shNF1_phenotype.cls#shNF1_versus_shCtrl_repos</td></tr><tr><td>Upregulated in class</td><td>shCtrl</td></tr><tr><td>GeneSet</td><td>NEFTEL_OPC_2019</td></tr><tr><td>Enrichment Score (ES)</td><td>-0.49214387</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>-1.7961828</td></tr><tr><td>Nominal p-value</td><td>0.0018083183</td></tr><tr><td>FDR q-value</td><td>0.002079226</td></tr><tr><td>FWER p-Value</td><td>0.01</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_NEFTEL_OPC_2019' src='enplot_NEFTEL_OPC_2019_51.png'><br><br><caption>Fig 1: Enrichment plot: NEFTEL_OPC_2019    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=ALCAM'>ALCAM</a></td><td>ALCAM</td><td>45</td><td>0.100</td><td>0.0472</td><td>No</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=VCAN'>VCAN</a></td><td>VCAN</td><td>54</td><td>0.099</td><td>0.0952</td><td>No</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=CNTN1'>CNTN1</a></td><td>CNTN1</td><td>452</td><td>0.063</td><td>0.1078</td><td>No</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=LIMA1'>LIMA1</a></td><td>LIMA1</td><td>552</td><td>0.060</td><td>0.1326</td><td>No</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=NKAIN4'>NKAIN4</a></td><td>NKAIN4</td><td>1339</td><td>0.045</td><td>0.1184</td><td>No</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=BCAS1'>BCAS1</a></td><td>BCAS1</td><td>2069</td><td>0.038</td><td>0.1032</td><td>No</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=EPB41L2'>EPB41L2</a></td><td>EPB41L2</td><td>2988</td><td>0.031</td><td>0.0759</td><td>No</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=OMG'>OMG</a></td><td>OMG</td><td>3005</td><td>0.031</td><td>0.0903</td><td>No</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=SCD5'>SCD5</a></td><td>SCD5</td><td>3812</td><td>0.026</td><td>0.0657</td><td>No</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=TNS3'>TNS3</a></td><td>TNS3</td><td>3849</td><td>0.026</td><td>0.0767</td><td>No</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=CNP'>CNP</a></td><td>CNP</td><td>4587</td><td>0.022</td><td>0.0533</td><td>No</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=FGF12'>FGF12</a></td><td>FGF12</td><td>5004</td><td>0.020</td><td>0.0440</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=LMF1'>LMF1</a></td><td>LMF1</td><td>6421</td><td>0.014</td><td>-0.0148</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=THY1'>THY1</a></td><td>THY1</td><td>6652</td><td>0.013</td><td>-0.0190</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=APOD'>APOD</a></td><td>APOD</td><td>6973</td><td>0.012</td><td>-0.0279</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=LHFPL3'>LHFPL3</a></td><td>LHFPL3</td><td>8340</td><td>0.007</td><td>-0.0877</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=PLP1'>PLP1</a></td><td>PLP1</td><td>9543</td><td>0.004</td><td>-0.1417</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=PGRMC1'>PGRMC1</a></td><td>PGRMC1</td><td>9583</td><td>0.003</td><td>-0.1419</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=CA10'>CA10</a></td><td>CA10</td><td>9972</td><td>0.002</td><td>-0.1589</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=PCDHGC3'>PCDHGC3</a></td><td>PCDHGC3</td><td>10698</td><td>-0.000</td><td>-0.1925</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=FABP5'>FABP5</a></td><td>FABP5</td><td>10933</td><td>-0.001</td><td>-0.2029</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=SIRT2'>SIRT2</a></td><td>SIRT2</td><td>11989</td><td>-0.004</td><td>-0.2497</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=RTKN'>RTKN</a></td><td>RTKN</td><td>12739</td><td>-0.007</td><td>-0.2811</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=P2RX7'>P2RX7</a></td><td>P2RX7</td><td>12774</td><td>-0.007</td><td>-0.2793</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=DBI'>DBI</a></td><td>DBI</td><td>13067</td><td>-0.008</td><td>-0.2890</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=SERINC5'>SERINC5</a></td><td>SERINC5</td><td>13375</td><td>-0.009</td><td>-0.2989</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=RNF13'>RNF13</a></td><td>RNF13</td><td>14728</td><td>-0.014</td><td>-0.3549</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=HRASLS'>HRASLS</a></td><td>HRASLS</td><td>14793</td><td>-0.014</td><td>-0.3510</td><td>No</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=RAB31'>RAB31</a></td><td>RAB31</td><td>15883</td><td>-0.018</td><td>-0.3925</td><td>No</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=LPPR1'>LPPR1</a></td><td>LPPR1</td><td>16449</td><td>-0.021</td><td>-0.4084</td><td>No</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=GPM6B'>GPM6B</a></td><td>GPM6B</td><td>16474</td><td>-0.021</td><td>-0.3991</td><td>No</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=CADM2'>CADM2</a></td><td>CADM2</td><td>17989</td><td>-0.029</td><td>-0.4551</td><td>No</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=TNR'>TNR</a></td><td>TNR</td><td>18665</td><td>-0.033</td><td>-0.4702</td><td>No</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=PTPRZ1'>PTPRZ1</a></td><td>PTPRZ1</td><td>18797</td><td>-0.034</td><td>-0.4595</td><td>No</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=GPR17'>GPR17</a></td><td>GPR17</td><td>19501</td><td>-0.039</td><td>-0.4728</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=TMEM206'>TMEM206</a></td><td>TMEM206</td><td>19703</td><td>-0.041</td><td>-0.4619</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=NLGN3'>NLGN3</a></td><td>NLGN3</td><td>20159</td><td>-0.046</td><td>-0.4603</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=BCAN'>BCAN</a></td><td>BCAN</td><td>20254</td><td>-0.048</td><td>-0.4414</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=SCRG1'>SCRG1</a></td><td>SCRG1</td><td>20553</td><td>-0.052</td><td>-0.4295</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=PSAT1'>PSAT1</a></td><td>PSAT1</td><td>20748</td><td>-0.056</td><td>-0.4109</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=FIBIN'>FIBIN</a></td><td>FIBIN</td><td>21159</td><td>-0.069</td><td>-0.3963</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=PLLP'>PLLP</a></td><td>PLLP</td><td>21296</td><td>-0.075</td><td>-0.3659</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=PHYHIPL'>PHYHIPL</a></td><td>PHYHIPL</td><td>21383</td><td>-0.082</td><td>-0.3298</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=FXYD6'>FXYD6</a></td><td>FXYD6</td><td>21404</td><td>-0.084</td><td>-0.2897</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>45</td><td><a href='https://ensembl.org/Search/Results?q=GPR37L1'>GPR37L1</a></td><td>GPR37L1</td><td>21472</td><td>-0.093</td><td>-0.2471</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>46</td><td><a href='https://ensembl.org/Search/Results?q=OLIG1'>OLIG1</a></td><td>OLIG1</td><td>21528</td><td>-0.106</td><td>-0.1978</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>47</td><td><a href='https://ensembl.org/Search/Results?q=NEU4'>NEU4</a></td><td>NEU4</td><td>21549</td><td>-0.115</td><td>-0.1422</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>48</td><td><a href='https://ensembl.org/Search/Results?q=TTYH1'>TTYH1</a></td><td>TTYH1</td><td>21573</td><td>-0.137</td><td>-0.0761</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>49</td><td><a href='https://ensembl.org/Search/Results?q=PMP2'>PMP2</a></td><td>PMP2</td><td>21584</td><td>-0.157</td><td>0.0006</td><td bgcolor='#CCFFCC'>Yes</td></tr><caption class='table'>Table: GSEA details <a href='NEFTEL_OPC_2019.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='NEFTEL_OPC_2019' src='NEFTEL_OPC_2019_52.png'><br><br><caption>Fig 2: NEFTEL_OPC_2019    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_53.png'><br><br><caption>Fig 3: NEFTEL_OPC_2019: Random ES distribution    <br> Gene set null distribution of ES for <b>NEFTEL_OPC_2019</b></caption></div><br></body></html>