<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set WANG_CL_2017[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>shNF1_exprs.shNF1_phenotype.cls<br>#shNF1_versus_shCtrl.shNF1_phenotype.cls<br>#shNF1_versus_shCtrl_repos</td></tr><tr><td>Phenotype</td><td>shNF1_phenotype.cls#shNF1_versus_shCtrl_repos</td></tr><tr><td>Upregulated in class</td><td>shCtrl</td></tr><tr><td>GeneSet</td><td>WANG_CL_2017</td></tr><tr><td>Enrichment Score (ES)</td><td>-0.2843758</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>-1.0366416</td></tr><tr><td>Nominal p-value</td><td>0.3882784</td></tr><tr><td>FDR q-value</td><td>0.4323487</td></tr><tr><td>FWER p-Value</td><td>1.0</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_WANG_CL_2017' src='enplot_WANG_CL_2017_87.png'><br><br><caption>Fig 1: Enrichment plot: WANG_CL_2017    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=PNPLA6'>PNPLA6</a></td><td>PNPLA6</td><td>63</td><td>0.096</td><td>0.0662</td><td>No</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=PHKB'>PHKB</a></td><td>PHKB</td><td>444</td><td>0.064</td><td>0.0943</td><td>No</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=ZNF45'>ZNF45</a></td><td>ZNF45</td><td>1157</td><td>0.048</td><td>0.0956</td><td>No</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=GRIK1'>GRIK1</a></td><td>GRIK1</td><td>1270</td><td>0.046</td><td>0.1237</td><td>No</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=UPF1'>UPF1</a></td><td>UPF1</td><td>1535</td><td>0.043</td><td>0.1423</td><td>No</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=TJP1'>TJP1</a></td><td>TJP1</td><td>1858</td><td>0.040</td><td>0.1560</td><td>No</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=PLCG1'>PLCG1</a></td><td>PLCG1</td><td>2560</td><td>0.034</td><td>0.1479</td><td>No</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=SOX9'>SOX9</a></td><td>SOX9</td><td>2786</td><td>0.032</td><td>0.1607</td><td>No</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=ZFHX4'>ZFHX4</a></td><td>ZFHX4</td><td>3078</td><td>0.031</td><td>0.1691</td><td>No</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=SLC20A2'>SLC20A2</a></td><td>SLC20A2</td><td>4204</td><td>0.024</td><td>0.1341</td><td>No</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=BBS1'>BBS1</a></td><td>BBS1</td><td>4501</td><td>0.023</td><td>0.1365</td><td>No</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=DENND2A'>DENND2A</a></td><td>DENND2A</td><td>4698</td><td>0.022</td><td>0.1430</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=POLRMT'>POLRMT</a></td><td>POLRMT</td><td>5040</td><td>0.020</td><td>0.1415</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=CTNND1'>CTNND1</a></td><td>CTNND1</td><td>5629</td><td>0.017</td><td>0.1267</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=TYK2'>TYK2</a></td><td>TYK2</td><td>6134</td><td>0.015</td><td>0.1143</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=ACSL3'>ACSL3</a></td><td>ACSL3</td><td>6283</td><td>0.015</td><td>0.1180</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=CDH4'>CDH4</a></td><td>CDH4</td><td>6379</td><td>0.014</td><td>0.1239</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=USP8'>USP8</a></td><td>USP8</td><td>6609</td><td>0.013</td><td>0.1229</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=PLCE1'>PLCE1</a></td><td>PLCE1</td><td>7640</td><td>0.010</td><td>0.0821</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=ACSBG1'>ACSBG1</a></td><td>ACSBG1</td><td>7763</td><td>0.009</td><td>0.0832</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=PTPRA'>PTPRA</a></td><td>PTPRA</td><td>8701</td><td>0.006</td><td>0.0442</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=SPRY2'>SPRY2</a></td><td>SPRY2</td><td>9196</td><td>0.005</td><td>0.0246</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=STXBP3'>STXBP3</a></td><td>STXBP3</td><td>10244</td><td>0.001</td><td>-0.0231</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=SALL1'>SALL1</a></td><td>SALL1</td><td>10618</td><td>0.000</td><td>-0.0404</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=KIAA0494'>KIAA0494</a></td><td>KIAA0494</td><td>10644</td><td>0.000</td><td>-0.0415</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=ELOVL2'>ELOVL2</a></td><td>ELOVL2</td><td>10941</td><td>-0.001</td><td>-0.0546</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=SEPT11'>SEPT11</a></td><td>SEPT11</td><td>11067</td><td>-0.001</td><td>-0.0595</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=C14orf159'>C14orf159</a></td><td>C14orf159</td><td>11401</td><td>-0.002</td><td>-0.0732</td><td>No</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=DTNA'>DTNA</a></td><td>DTNA</td><td>11438</td><td>-0.003</td><td>-0.0731</td><td>No</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=GATM'>GATM</a></td><td>GATM</td><td>11519</td><td>-0.003</td><td>-0.0748</td><td>No</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=NCOA1'>NCOA1</a></td><td>NCOA1</td><td>11530</td><td>-0.003</td><td>-0.0732</td><td>No</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=MEOX2'>MEOX2</a></td><td>MEOX2</td><td>14875</td><td>-0.014</td><td>-0.2182</td><td>No</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=LHFP'>LHFP</a></td><td>LHFP</td><td>14968</td><td>-0.015</td><td>-0.2119</td><td>No</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=EYA2'>EYA2</a></td><td>EYA2</td><td>15194</td><td>-0.016</td><td>-0.2111</td><td>No</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=ARNTL'>ARNTL</a></td><td>ARNTL</td><td>16153</td><td>-0.020</td><td>-0.2414</td><td>No</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=NPEPL1'>NPEPL1</a></td><td>NPEPL1</td><td>16370</td><td>-0.021</td><td>-0.2366</td><td>No</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=ABLIM1'>ABLIM1</a></td><td>ABLIM1</td><td>16439</td><td>-0.021</td><td>-0.2247</td><td>No</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=PPARGC1A'>PPARGC1A</a></td><td>PPARGC1A</td><td>16746</td><td>-0.023</td><td>-0.2227</td><td>No</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=RASGRP1'>RASGRP1</a></td><td>RASGRP1</td><td>17176</td><td>-0.024</td><td>-0.2251</td><td>No</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=FGFR3'>FGFR3</a></td><td>FGFR3</td><td>17239</td><td>-0.025</td><td>-0.2102</td><td>No</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=MYO5C'>MYO5C</a></td><td>MYO5C</td><td>17998</td><td>-0.029</td><td>-0.2244</td><td>No</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=RBCK1'>RBCK1</a></td><td>RBCK1</td><td>18696</td><td>-0.033</td><td>-0.2327</td><td>No</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=ZHX3'>ZHX3</a></td><td>ZHX3</td><td>19794</td><td>-0.042</td><td>-0.2534</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=CST3'>CST3</a></td><td>CST3</td><td>20462</td><td>-0.051</td><td>-0.2479</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>45</td><td><a href='https://ensembl.org/Search/Results?q=SLC3A2'>SLC3A2</a></td><td>SLC3A2</td><td>20700</td><td>-0.055</td><td>-0.2192</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>46</td><td><a href='https://ensembl.org/Search/Results?q=PAX6'>PAX6</a></td><td>PAX6</td><td>20768</td><td>-0.057</td><td>-0.1816</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>47</td><td><a href='https://ensembl.org/Search/Results?q=MLC1'>MLC1</a></td><td>MLC1</td><td>20941</td><td>-0.061</td><td>-0.1459</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>48</td><td><a href='https://ensembl.org/Search/Results?q=BCKDHB'>BCKDHB</a></td><td>BCKDHB</td><td>21194</td><td>-0.070</td><td>-0.1075</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>49</td><td><a href='https://ensembl.org/Search/Results?q=SLC4A4'>SLC4A4</a></td><td>SLC4A4</td><td>21238</td><td>-0.072</td><td>-0.0579</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>50</td><td><a href='https://ensembl.org/Search/Results?q=VAV3'>VAV3</a></td><td>VAV3</td><td>21521</td><td>-0.104</td><td>0.0035</td><td bgcolor='#CCFFCC'>Yes</td></tr><caption class='table'>Table: GSEA details <a href='WANG_CL_2017.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='WANG_CL_2017' src='WANG_CL_2017_88.png'><br><br><caption>Fig 2: WANG_CL_2017    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_89.png'><br><br><caption>Fig 3: WANG_CL_2017: Random ES distribution    <br> Gene set null distribution of ES for <b>WANG_CL_2017</b></caption></div><br></body></html>