<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set WANG_MES_2017[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>shNF1_exprs.shNF1_phenotype.cls<br>#shNF1_versus_shCtrl.shNF1_phenotype.cls<br>#shNF1_versus_shCtrl_repos</td></tr><tr><td>Phenotype</td><td>shNF1_phenotype.cls#shNF1_versus_shCtrl_repos</td></tr><tr><td>Upregulated in class</td><td>shNF1</td></tr><tr><td>GeneSet</td><td>WANG_MES_2017</td></tr><tr><td>Enrichment Score (ES)</td><td>0.4302045</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>1.6611276</td></tr><tr><td>Nominal p-value</td><td>0.009049774</td></tr><tr><td>FDR q-value</td><td>0.004547161</td></tr><tr><td>FWER p-Value</td><td>0.03</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_WANG_MES_2017' src='enplot_WANG_MES_2017_18.png'><br><br><caption>Fig 1: Enrichment plot: WANG_MES_2017    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=THBS1'>THBS1</a></td><td>THBS1</td><td>13</td><td>0.123</td><td>0.0972</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=BNC2'>BNC2</a></td><td>BNC2</td><td>40</td><td>0.102</td><td>0.1769</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=COL1A1'>COL1A1</a></td><td>COL1A1</td><td>158</td><td>0.082</td><td>0.2365</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=IL7R'>IL7R</a></td><td>IL7R</td><td>279</td><td>0.072</td><td>0.2878</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=COL1A2'>COL1A2</a></td><td>COL1A2</td><td>651</td><td>0.057</td><td>0.3160</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=CAV1'>CAV1</a></td><td>CAV1</td><td>814</td><td>0.054</td><td>0.3514</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=ITGB1'>ITGB1</a></td><td>ITGB1</td><td>957</td><td>0.051</td><td>0.3854</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=LOX'>LOX</a></td><td>LOX</td><td>1391</td><td>0.045</td><td>0.4007</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=PI3'>PI3</a></td><td>PI3</td><td>1922</td><td>0.039</td><td>0.4073</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=NDRG1'>NDRG1</a></td><td>NDRG1</td><td>2507</td><td>0.034</td><td>0.4074</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=CD72'>CD72</a></td><td>CD72</td><td>2847</td><td>0.032</td><td>0.4170</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=ACPP'>ACPP</a></td><td>ACPP</td><td>3084</td><td>0.030</td><td>0.4302</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=TGFBI'>TGFBI</a></td><td>TGFBI</td><td>4792</td><td>0.021</td><td>0.3678</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=CNN2'>CNN2</a></td><td>CNN2</td><td>5091</td><td>0.020</td><td>0.3696</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=SLPI'>SLPI</a></td><td>SLPI</td><td>5413</td><td>0.018</td><td>0.3693</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=TNFAIP8'>TNFAIP8</a></td><td>TNFAIP8</td><td>5465</td><td>0.018</td><td>0.3813</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=GLIPR1'>GLIPR1</a></td><td>GLIPR1</td><td>5605</td><td>0.017</td><td>0.3887</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=IL6'>IL6</a></td><td>IL6</td><td>5609</td><td>0.017</td><td>0.4023</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=CTSC'>CTSC</a></td><td>CTSC</td><td>6083</td><td>0.016</td><td>0.3927</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=ARPC1B'>ARPC1B</a></td><td>ARPC1B</td><td>6192</td><td>0.015</td><td>0.3997</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=RAB27A'>RAB27A</a></td><td>RAB27A</td><td>6204</td><td>0.015</td><td>0.4111</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=CDCP1'>CDCP1</a></td><td>CDCP1</td><td>6238</td><td>0.015</td><td>0.4213</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=P4HA2'>P4HA2</a></td><td>P4HA2</td><td>7058</td><td>0.012</td><td>0.3926</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=PLAUR'>PLAUR</a></td><td>PLAUR</td><td>7477</td><td>0.010</td><td>0.3814</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=CYP1B1'>CYP1B1</a></td><td>CYP1B1</td><td>7673</td><td>0.010</td><td>0.3801</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=IER3'>IER3</a></td><td>IER3</td><td>8602</td><td>0.007</td><td>0.3422</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=RGS2'>RGS2</a></td><td>RGS2</td><td>9049</td><td>0.005</td><td>0.3255</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=SYNGR2'>SYNGR2</a></td><td>SYNGR2</td><td>9437</td><td>0.004</td><td>0.3107</td><td>No</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=BCL3'>BCL3</a></td><td>BCL3</td><td>9852</td><td>0.002</td><td>0.2934</td><td>No</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=ANPEP'>ANPEP</a></td><td>ANPEP</td><td>9908</td><td>0.002</td><td>0.2926</td><td>No</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=S100A11'>S100A11</a></td><td>S100A11</td><td>10703</td><td>-0.000</td><td>0.2559</td><td>No</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=SDC1'>SDC1</a></td><td>SDC1</td><td>11233</td><td>-0.002</td><td>0.2327</td><td>No</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=PTGS2'>PTGS2</a></td><td>PTGS2</td><td>11356</td><td>-0.002</td><td>0.2289</td><td>No</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=RARRES1'>RARRES1</a></td><td>RARRES1</td><td>11546</td><td>-0.003</td><td>0.2224</td><td>No</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=GPRC5A'>GPRC5A</a></td><td>GPRC5A</td><td>11746</td><td>-0.004</td><td>0.2159</td><td>No</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=RUNX1'>RUNX1</a></td><td>RUNX1</td><td>12042</td><td>-0.005</td><td>0.2059</td><td>No</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=COL15A1'>COL15A1</a></td><td>COL15A1</td><td>12302</td><td>-0.005</td><td>0.1981</td><td>No</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=PRSS23'>PRSS23</a></td><td>PRSS23</td><td>12359</td><td>-0.006</td><td>0.2000</td><td>No</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=CTSB'>CTSB</a></td><td>CTSB</td><td>12661</td><td>-0.007</td><td>0.1912</td><td>No</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=COL5A1'>COL5A1</a></td><td>COL5A1</td><td>14074</td><td>-0.011</td><td>0.1346</td><td>No</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=LY96'>LY96</a></td><td>LY96</td><td>14269</td><td>-0.012</td><td>0.1351</td><td>No</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=BACE2'>BACE2</a></td><td>BACE2</td><td>15352</td><td>-0.016</td><td>0.0977</td><td>No</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=SPAG4'>SPAG4</a></td><td>SPAG4</td><td>16140</td><td>-0.020</td><td>0.0768</td><td>No</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=COL3A1'>COL3A1</a></td><td>COL3A1</td><td>16349</td><td>-0.021</td><td>0.0834</td><td>No</td></tr><tr><td class='lessen'>45</td><td><a href='https://ensembl.org/Search/Results?q=MMP7'>MMP7</a></td><td>MMP7</td><td>16754</td><td>-0.023</td><td>0.0825</td><td>No</td></tr><tr><td class='lessen'>46</td><td><a href='https://ensembl.org/Search/Results?q=VDR'>VDR</a></td><td>VDR</td><td>17575</td><td>-0.027</td><td>0.0656</td><td>No</td></tr><tr><td class='lessen'>47</td><td><a href='https://ensembl.org/Search/Results?q=FTL'>FTL</a></td><td>FTL</td><td>17640</td><td>-0.027</td><td>0.0841</td><td>No</td></tr><tr><td class='lessen'>48</td><td><a href='https://ensembl.org/Search/Results?q=LUM'>LUM</a></td><td>LUM</td><td>18137</td><td>-0.030</td><td>0.0848</td><td>No</td></tr><tr><td class='lessen'>49</td><td><a href='https://ensembl.org/Search/Results?q=NNMT'>NNMT</a></td><td>NNMT</td><td>18514</td><td>-0.032</td><td>0.0929</td><td>No</td></tr><tr><td class='lessen'>50</td><td><a href='https://ensembl.org/Search/Results?q=RAC2'>RAC2</a></td><td>RAC2</td><td>21019</td><td>-0.063</td><td>0.0268</td><td>No</td></tr><caption class='table'>Table: GSEA details <a href='WANG_MES_2017.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='WANG_MES_2017' src='WANG_MES_2017_19.png'><br><br><caption>Fig 2: WANG_MES_2017    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_20.png'><br><br><caption>Fig 3: WANG_MES_2017: Random ES distribution    <br> Gene set null distribution of ES for <b>WANG_MES_2017</b></caption></div><br></body></html>