<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set WANG_PN_2017[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>shNF1_exprs.shNF1_phenotype.cls<br>#shNF1_versus_shCtrl.shNF1_phenotype.cls<br>#shNF1_versus_shCtrl_repos</td></tr><tr><td>Phenotype</td><td>shNF1_phenotype.cls#shNF1_versus_shCtrl_repos</td></tr><tr><td>Upregulated in class</td><td>shCtrl</td></tr><tr><td>GeneSet</td><td>WANG_PN_2017</td></tr><tr><td>Enrichment Score (ES)</td><td>-0.2717626</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>-1.0216365</td></tr><tr><td>Nominal p-value</td><td>0.4257603</td></tr><tr><td>FDR q-value</td><td>0.44682175</td></tr><tr><td>FWER p-Value</td><td>1.0</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_WANG_PN_2017' src='enplot_WANG_PN_2017_90.png'><br><br><caption>Fig 1: Enrichment plot: WANG_PN_2017    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=DACH1'>DACH1</a></td><td>DACH1</td><td>2162</td><td>0.037</td><td>-0.0619</td><td>No</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=HDAC2'>HDAC2</a></td><td>HDAC2</td><td>2530</td><td>0.034</td><td>-0.0436</td><td>No</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=CDKN1C'>CDKN1C</a></td><td>CDKN1C</td><td>3368</td><td>0.029</td><td>-0.0528</td><td>No</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=HOXD3'>HOXD3</a></td><td>HOXD3</td><td>3432</td><td>0.028</td><td>-0.0266</td><td>No</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=TCP1'>TCP1</a></td><td>TCP1</td><td>3438</td><td>0.028</td><td>0.0022</td><td>No</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=SLC1A1'>SLC1A1</a></td><td>SLC1A1</td><td>3612</td><td>0.027</td><td>0.0223</td><td>No</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=VIPR2'>VIPR2</a></td><td>VIPR2</td><td>3738</td><td>0.026</td><td>0.0438</td><td>No</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=PDGFRA'>PDGFRA</a></td><td>PDGFRA</td><td>4907</td><td>0.021</td><td>0.0110</td><td>No</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=PAK7'>PAK7</a></td><td>PAK7</td><td>5215</td><td>0.019</td><td>0.0167</td><td>No</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=PCDHA9'>PCDHA9</a></td><td>PCDHA9</td><td>6312</td><td>0.015</td><td>-0.0192</td><td>No</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=GRID2'>GRID2</a></td><td>GRID2</td><td>6874</td><td>0.012</td><td>-0.0323</td><td>No</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=SLC17A6'>SLC17A6</a></td><td>SLC17A6</td><td>7494</td><td>0.010</td><td>-0.0504</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=NMU'>NMU</a></td><td>NMU</td><td>7508</td><td>0.010</td><td>-0.0404</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=KLRC4'>KLRC4</a></td><td>KLRC4</td><td>7526</td><td>0.010</td><td>-0.0307</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=NPPA'>NPPA</a></td><td>NPPA</td><td>8364</td><td>0.007</td><td>-0.0619</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=KLRK1'>KLRK1</a></td><td>KLRK1</td><td>9147</td><td>0.005</td><td>-0.0932</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=CLGN'>CLGN</a></td><td>CLGN</td><td>9585</td><td>0.003</td><td>-0.1100</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=SOX10'>SOX10</a></td><td>SOX10</td><td>9761</td><td>0.003</td><td>-0.1153</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=CA10'>CA10</a></td><td>CA10</td><td>9972</td><td>0.002</td><td>-0.1229</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=KLRC3'>KLRC3</a></td><td>KLRC3</td><td>10008</td><td>0.002</td><td>-0.1225</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=NHLH1'>NHLH1</a></td><td>NHLH1</td><td>10987</td><td>-0.001</td><td>-0.1668</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=IL1RAPL1'>IL1RAPL1</a></td><td>IL1RAPL1</td><td>11319</td><td>-0.002</td><td>-0.1800</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=NARF'>NARF</a></td><td>NARF</td><td>11359</td><td>-0.002</td><td>-0.1795</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=ZNF643'>ZNF643</a></td><td>ZNF643</td><td>11822</td><td>-0.004</td><td>-0.1970</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=UGT8'>UGT8</a></td><td>UGT8</td><td>12182</td><td>-0.005</td><td>-0.2085</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=PLCB4'>PLCB4</a></td><td>PLCB4</td><td>12472</td><td>-0.006</td><td>-0.2157</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=PKMYT1'>PKMYT1</a></td><td>PKMYT1</td><td>13029</td><td>-0.008</td><td>-0.2335</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=CENPJ'>CENPJ</a></td><td>CENPJ</td><td>13355</td><td>-0.009</td><td>-0.2395</td><td>No</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=MYB'>MYB</a></td><td>MYB</td><td>13495</td><td>-0.009</td><td>-0.2363</td><td>No</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=SMPD3'>SMPD3</a></td><td>SMPD3</td><td>14028</td><td>-0.011</td><td>-0.2495</td><td>No</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=ERBB3'>ERBB3</a></td><td>ERBB3</td><td>14471</td><td>-0.013</td><td>-0.2569</td><td>No</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=HRASLS'>HRASLS</a></td><td>HRASLS</td><td>14793</td><td>-0.014</td><td>-0.2573</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=SIM2'>SIM2</a></td><td>SIM2</td><td>14802</td><td>-0.014</td><td>-0.2432</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=BCL11A'>BCL11A</a></td><td>BCL11A</td><td>14866</td><td>-0.014</td><td>-0.2314</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=PTTG1'>PTTG1</a></td><td>PTTG1</td><td>15106</td><td>-0.015</td><td>-0.2267</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=MYT1'>MYT1</a></td><td>MYT1</td><td>15328</td><td>-0.016</td><td>-0.2204</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=GABRB3'>GABRB3</a></td><td>GABRB3</td><td>15373</td><td>-0.016</td><td>-0.2056</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=ZNF804A'>ZNF804A</a></td><td>ZNF804A</td><td>15432</td><td>-0.017</td><td>-0.1911</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=EPHB1'>EPHB1</a></td><td>EPHB1</td><td>15812</td><td>-0.018</td><td>-0.1899</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=HN1'>HN1</a></td><td>HN1</td><td>16160</td><td>-0.020</td><td>-0.1856</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=JPH3'>JPH3</a></td><td>JPH3</td><td>17299</td><td>-0.025</td><td>-0.2123</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=DCTN3'>DCTN3</a></td><td>DCTN3</td><td>17638</td><td>-0.027</td><td>-0.2001</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=KCNK3'>KCNK3</a></td><td>KCNK3</td><td>17795</td><td>-0.028</td><td>-0.1784</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=PFDN2'>PFDN2</a></td><td>PFDN2</td><td>17830</td><td>-0.028</td><td>-0.1509</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>45</td><td><a href='https://ensembl.org/Search/Results?q=MAST1'>MAST1</a></td><td>MAST1</td><td>18212</td><td>-0.030</td><td>-0.1370</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>46</td><td><a href='https://ensembl.org/Search/Results?q=GPR17'>GPR17</a></td><td>GPR17</td><td>19501</td><td>-0.039</td><td>-0.1561</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>47</td><td><a href='https://ensembl.org/Search/Results?q=RAB33A'>RAB33A</a></td><td>RAB33A</td><td>19565</td><td>-0.040</td><td>-0.1177</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>48</td><td><a href='https://ensembl.org/Search/Results?q=MTSS1'>MTSS1</a></td><td>MTSS1</td><td>20289</td><td>-0.048</td><td>-0.1015</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>49</td><td><a href='https://ensembl.org/Search/Results?q=RASL11B'>RASL11B</a></td><td>RASL11B</td><td>20713</td><td>-0.056</td><td>-0.0637</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>50</td><td><a href='https://ensembl.org/Search/Results?q=BAMBI'>BAMBI</a></td><td>BAMBI</td><td>21510</td><td>-0.101</td><td>0.0040</td><td bgcolor='#CCFFCC'>Yes</td></tr><caption class='table'>Table: GSEA details <a href='WANG_PN_2017.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='WANG_PN_2017' src='WANG_PN_2017_91.png'><br><br><caption>Fig 2: WANG_PN_2017    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_92.png'><br><br><caption>Fig 3: WANG_PN_2017: Random ES distribution    <br> Gene set null distribution of ES for <b>WANG_PN_2017</b></caption></div><br></body></html>