<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set NEFTEL_MES1_2019[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>NSCs_shNf1_sgFosl1.NSCs_shNf1_sgFosl1.cls<br>#Fosl1_versus_Ctrl.NSCs_shNf1_sgFosl1.cls<br>#Fosl1_versus_Ctrl_repos</td></tr><tr><td>Phenotype</td><td>NSCs_shNf1_sgFosl1.cls#Fosl1_versus_Ctrl_repos</td></tr><tr><td>Upregulated in class</td><td>Fosl1</td></tr><tr><td>GeneSet</td><td>NEFTEL_MES1_2019</td></tr><tr><td>Enrichment Score (ES)</td><td>0.34221283</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>0.86636484</td></tr><tr><td>Nominal p-value</td><td>0.6911765</td></tr><tr><td>FDR q-value</td><td>0.7424249</td></tr><tr><td>FWER p-Value</td><td>0.994</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_NEFTEL_MES1_2019' src='enplot_NEFTEL_MES1_2019_210.png'><br><br><caption>Fig 1: Enrichment plot: NEFTEL_MES1_2019    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=MGP'>MGP</a></td><td>MGP</td><td>163</td><td>0.761</td><td>0.1043</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=C3'>C3</a></td><td>C3</td><td>228</td><td>0.660</td><td>0.1979</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=IGFBP7'>IGFBP7</a></td><td>IGFBP7</td><td>470</td><td>0.540</td><td>0.2667</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=SERPING1'>SERPING1</a></td><td>SERPING1</td><td>497</td><td>0.525</td><td>0.3422</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=EFEMP1'>EFEMP1</a></td><td>EFEMP1</td><td>2632</td><td>0.232</td><td>0.2884</td><td>No</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=GFPT2'>GFPT2</a></td><td>GFPT2</td><td>3109</td><td>0.175</td><td>0.2943</td><td>No</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=TIMP1'>TIMP1</a></td><td>TIMP1</td><td>3528</td><td>0.139</td><td>0.2974</td><td>No</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=APOE'>APOE</a></td><td>APOE</td><td>5860</td><td>0.053</td><td>0.2094</td><td>No</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=TNFRSF1A'>TNFRSF1A</a></td><td>TNFRSF1A</td><td>6759</td><td>0.039</td><td>0.1782</td><td>No</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=PRDX6'>PRDX6</a></td><td>PRDX6</td><td>6909</td><td>0.037</td><td>0.1774</td><td>No</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=S100A16'>S100A16</a></td><td>S100A16</td><td>8087</td><td>0.023</td><td>0.1324</td><td>No</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=S100A10'>S100A10</a></td><td>S100A10</td><td>8879</td><td>0.015</td><td>0.1021</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=GSN'>GSN</a></td><td>GSN</td><td>9091</td><td>0.013</td><td>0.0954</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=TAGLN2'>TAGLN2</a></td><td>TAGLN2</td><td>9367</td><td>0.011</td><td>0.0857</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=ANXA1'>ANXA1</a></td><td>ANXA1</td><td>10276</td><td>0.003</td><td>0.0489</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=SOD2'>SOD2</a></td><td>SOD2</td><td>14901</td><td>-0.001</td><td>-0.1410</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=SERPINE1'>SERPINE1</a></td><td>SERPINE1</td><td>15830</td><td>-0.009</td><td>-0.1778</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=EMP3'>EMP3</a></td><td>EMP3</td><td>16762</td><td>-0.018</td><td>-0.2133</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=CTSB'>CTSB</a></td><td>CTSB</td><td>17332</td><td>-0.025</td><td>-0.2330</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=RCAN1'>RCAN1</a></td><td>RCAN1</td><td>17353</td><td>-0.025</td><td>-0.2302</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=NPC2'>NPC2</a></td><td>NPC2</td><td>17773</td><td>-0.031</td><td>-0.2428</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=WWTR1'>WWTR1</a></td><td>WWTR1</td><td>18020</td><td>-0.035</td><td>-0.2479</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=CLIC4'>CLIC4</a></td><td>CLIC4</td><td>18121</td><td>-0.036</td><td>-0.2467</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=CLIC1'>CLIC1</a></td><td>CLIC1</td><td>18140</td><td>-0.037</td><td>-0.2420</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=VIM'>VIM</a></td><td>VIM</td><td>18758</td><td>-0.049</td><td>-0.2602</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=TUBA1C'>TUBA1C</a></td><td>TUBA1C</td><td>18839</td><td>-0.051</td><td>-0.2560</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=IFITM3'>IFITM3</a></td><td>IFITM3</td><td>18918</td><td>-0.053</td><td>-0.2515</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=LGALS1'>LGALS1</a></td><td>LGALS1</td><td>18926</td><td>-0.053</td><td>-0.2440</td><td>No</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=GJA1'>GJA1</a></td><td>GJA1</td><td>19177</td><td>-0.061</td><td>-0.2454</td><td>No</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=MGST1'>MGST1</a></td><td>MGST1</td><td>19380</td><td>-0.068</td><td>-0.2439</td><td>No</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=NAMPT'>NAMPT</a></td><td>NAMPT</td><td>19644</td><td>-0.077</td><td>-0.2434</td><td>No</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=PLP2'>PLP2</a></td><td>PLP2</td><td>19799</td><td>-0.084</td><td>-0.2375</td><td>No</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=CD44'>CD44</a></td><td>CD44</td><td>19954</td><td>-0.091</td><td>-0.2305</td><td>No</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=EMP1'>EMP1</a></td><td>EMP1</td><td>21196</td><td>-0.170</td><td>-0.2567</td><td>No</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=A2M'>A2M</a></td><td>A2M</td><td>21880</td><td>-0.251</td><td>-0.2482</td><td>No</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=NNMT'>NNMT</a></td><td>NNMT</td><td>21893</td><td>-0.253</td><td>-0.2118</td><td>No</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=ACTN1'>ACTN1</a></td><td>ACTN1</td><td>21926</td><td>-0.257</td><td>-0.1755</td><td>No</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=FN1'>FN1</a></td><td>FN1</td><td>22337</td><td>-0.329</td><td>-0.1443</td><td>No</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=ANXA2'>ANXA2</a></td><td>ANXA2</td><td>22374</td><td>-0.334</td><td>-0.0971</td><td>No</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=LGALS3'>LGALS3</a></td><td>LGALS3</td><td>22395</td><td>-0.340</td><td>-0.0484</td><td>No</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=SPP1'>SPP1</a></td><td>SPP1</td><td>23241</td><td>-0.405</td><td>-0.0240</td><td>No</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=S100A11'>S100A11</a></td><td>S100A11</td><td>23510</td><td>-0.487</td><td>0.0361</td><td>No</td></tr><caption class='table'>Table: GSEA details <a href='NEFTEL_MES1_2019.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='NEFTEL_MES1_2019' src='NEFTEL_MES1_2019_211.png'><br><br><caption>Fig 2: NEFTEL_MES1_2019    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_212.png'><br><br><caption>Fig 3: NEFTEL_MES1_2019: Random ES distribution    <br> Gene set null distribution of ES for <b>NEFTEL_MES1_2019</b></caption></div><br></body></html>