<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set NEFTEL_MES2_2019[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>NSCs_shNf1_sgFosl1.NSCs_shNf1_sgFosl1.cls<br>#Fosl1_versus_Ctrl.NSCs_shNf1_sgFosl1.cls<br>#Fosl1_versus_Ctrl_repos</td></tr><tr><td>Phenotype</td><td>NSCs_shNf1_sgFosl1.cls#Fosl1_versus_Ctrl_repos</td></tr><tr><td>Upregulated in class</td><td>Ctrl</td></tr><tr><td>GeneSet</td><td>NEFTEL_MES2_2019</td></tr><tr><td>Enrichment Score (ES)</td><td>-0.6219788</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>-1.4487569</td></tr><tr><td>Nominal p-value</td><td>0.11776859</td></tr><tr><td>FDR q-value</td><td>0.08054946</td></tr><tr><td>FWER p-Value</td><td>0.31</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_NEFTEL_MES2_2019' src='enplot_NEFTEL_MES2_2019_237.png'><br><br><caption>Fig 1: Enrichment plot: NEFTEL_MES2_2019    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=AKAP12'>AKAP12</a></td><td>AKAP12</td><td>1492</td><td>0.288</td><td>0.0019</td><td>No</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=EPAS1'>EPAS1</a></td><td>EPAS1</td><td>6142</td><td>0.048</td><td>-0.1786</td><td>No</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=HILPDA'>HILPDA</a></td><td>HILPDA</td><td>6454</td><td>0.043</td><td>-0.1819</td><td>No</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=ENO2'>ENO2</a></td><td>ENO2</td><td>6922</td><td>0.036</td><td>-0.1931</td><td>No</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=SLC39A14'>SLC39A14</a></td><td>SLC39A14</td><td>7212</td><td>0.033</td><td>-0.1978</td><td>No</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=EGLN3'>EGLN3</a></td><td>EGLN3</td><td>7555</td><td>0.029</td><td>-0.2055</td><td>No</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=BNIP3L'>BNIP3L</a></td><td>BNIP3L</td><td>7687</td><td>0.027</td><td>-0.2049</td><td>No</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=TRAM1'>TRAM1</a></td><td>TRAM1</td><td>7843</td><td>0.026</td><td>-0.2057</td><td>No</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=INSIG2'>INSIG2</a></td><td>INSIG2</td><td>9269</td><td>0.012</td><td>-0.2616</td><td>No</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=RPL21'>RPL21</a></td><td>RPL21</td><td>9689</td><td>0.008</td><td>-0.2771</td><td>No</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=GOLT1B'>GOLT1B</a></td><td>GOLT1B</td><td>10182</td><td>0.004</td><td>-0.2965</td><td>No</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=LDHA'>LDHA</a></td><td>LDHA</td><td>14913</td><td>-0.001</td><td>-0.4906</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=UFM1'>UFM1</a></td><td>UFM1</td><td>15136</td><td>-0.003</td><td>-0.4991</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=PGK1'>PGK1</a></td><td>PGK1</td><td>15173</td><td>-0.003</td><td>-0.5000</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=P4HA1'>P4HA1</a></td><td>P4HA1</td><td>15374</td><td>-0.005</td><td>-0.5071</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=ERO1L'>ERO1L</a></td><td>ERO1L</td><td>15870</td><td>-0.009</td><td>-0.5254</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=HSPA5'>HSPA5</a></td><td>HSPA5</td><td>17529</td><td>-0.027</td><td>-0.5875</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=PLOD2'>PLOD2</a></td><td>PLOD2</td><td>18046</td><td>-0.035</td><td>-0.6010</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=GBE1'>GBE1</a></td><td>GBE1</td><td>18170</td><td>-0.037</td><td>-0.5979</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=VIM'>VIM</a></td><td>VIM</td><td>18758</td><td>-0.049</td><td>-0.6112</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=ANGPTL4'>ANGPTL4</a></td><td>ANGPTL4</td><td>18785</td><td>-0.050</td><td>-0.6013</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=XPOT'>XPOT</a></td><td>XPOT</td><td>19108</td><td>-0.058</td><td>-0.6017</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=ASNS'>ASNS</a></td><td>ASNS</td><td>19157</td><td>-0.060</td><td>-0.5906</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=BNIP3'>BNIP3</a></td><td>BNIP3</td><td>19174</td><td>-0.061</td><td>-0.5779</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=HSPA9'>HSPA9</a></td><td>HSPA9</td><td>19301</td><td>-0.065</td><td>-0.5689</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=DNAJB9'>DNAJB9</a></td><td>DNAJB9</td><td>19563</td><td>-0.074</td><td>-0.5634</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=NAMPT'>NAMPT</a></td><td>NAMPT</td><td>19644</td><td>-0.077</td><td>-0.5498</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=HERPUD1'>HERPUD1</a></td><td>HERPUD1</td><td>19678</td><td>-0.079</td><td>-0.5339</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=CDKN1A'>CDKN1A</a></td><td>CDKN1A</td><td>19702</td><td>-0.080</td><td>-0.5174</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=SLC6A6'>SLC6A6</a></td><td>SLC6A6</td><td>19866</td><td>-0.088</td><td>-0.5049</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=SERTAD1'>SERTAD1</a></td><td>SERTAD1</td><td>19991</td><td>-0.093</td><td>-0.4896</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=WARS'>WARS</a></td><td>WARS</td><td>19999</td><td>-0.094</td><td>-0.4694</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=SQSTM1'>SQSTM1</a></td><td>SQSTM1</td><td>20077</td><td>-0.098</td><td>-0.4511</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=NRN1'>NRN1</a></td><td>NRN1</td><td>20231</td><td>-0.104</td><td>-0.4346</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=PPP1R15A'>PPP1R15A</a></td><td>PPP1R15A</td><td>20271</td><td>-0.105</td><td>-0.4131</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=TRIB3'>TRIB3</a></td><td>TRIB3</td><td>20741</td><td>-0.129</td><td>-0.4041</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=IGFBP3'>IGFBP3</a></td><td>IGFBP3</td><td>20754</td><td>-0.131</td><td>-0.3759</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=PFKP'>PFKP</a></td><td>PFKP</td><td>20816</td><td>-0.135</td><td>-0.3490</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=ADM'>ADM</a></td><td>ADM</td><td>20911</td><td>-0.142</td><td>-0.3218</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=DDIT3'>DDIT3</a></td><td>DDIT3</td><td>21180</td><td>-0.168</td><td>-0.2959</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=SLC2A1'>SLC2A1</a></td><td>SLC2A1</td><td>21216</td><td>-0.173</td><td>-0.2595</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=ATF3'>ATF3</a></td><td>ATF3</td><td>21368</td><td>-0.190</td><td>-0.2241</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=GDF15'>GDF15</a></td><td>GDF15</td><td>21822</td><td>-0.242</td><td>-0.1896</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=SLC2A3'>SLC2A3</a></td><td>SLC2A3</td><td>22057</td><td>-0.278</td><td>-0.1383</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>45</td><td><a href='https://ensembl.org/Search/Results?q=ANXA2'>ANXA2</a></td><td>ANXA2</td><td>22374</td><td>-0.334</td><td>-0.0780</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>46</td><td><a href='https://ensembl.org/Search/Results?q=LGALS3'>LGALS3</a></td><td>LGALS3</td><td>22395</td><td>-0.340</td><td>-0.0044</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>47</td><td><a href='https://ensembl.org/Search/Results?q=NDRG1'>NDRG1</a></td><td>NDRG1</td><td>23143</td><td>-0.394</td><td>0.0511</td><td bgcolor='#CCFFCC'>Yes</td></tr><caption class='table'>Table: GSEA details <a href='NEFTEL_MES2_2019.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='NEFTEL_MES2_2019' src='NEFTEL_MES2_2019_238.png'><br><br><caption>Fig 2: NEFTEL_MES2_2019    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_239.png'><br><br><caption>Fig 3: NEFTEL_MES2_2019: Random ES distribution    <br> Gene set null distribution of ES for <b>NEFTEL_MES2_2019</b></caption></div><br></body></html>