<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set NEFTEL_NPC1_2019[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>NSCs_shNf1_sgFosl1.NSCs_shNf1_sgFosl1.cls<br>#Fosl1_versus_Ctrl.NSCs_shNf1_sgFosl1.cls<br>#Fosl1_versus_Ctrl_repos</td></tr><tr><td>Phenotype</td><td>NSCs_shNf1_sgFosl1.cls#Fosl1_versus_Ctrl_repos</td></tr><tr><td>Upregulated in class</td><td>Fosl1</td></tr><tr><td>GeneSet</td><td>NEFTEL_NPC1_2019</td></tr><tr><td>Enrichment Score (ES)</td><td>0.56468004</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>1.4003693</td></tr><tr><td>Nominal p-value</td><td>0.16666667</td></tr><tr><td>FDR q-value</td><td>0.40732482</td></tr><tr><td>FWER p-Value</td><td>0.375</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_NEFTEL_NPC1_2019' src='enplot_NEFTEL_NPC1_2019_189.png'><br><br><caption>Fig 1: Enrichment plot: NEFTEL_NPC1_2019    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=MYT1'>MYT1</a></td><td>MYT1</td><td>772</td><td>0.427</td><td>0.0683</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=TNR'>TNR</a></td><td>TNR</td><td>1688</td><td>0.258</td><td>0.0911</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=NXPH1'>NXPH1</a></td><td>NXPH1</td><td>2700</td><td>0.221</td><td>0.1015</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=FXYD6'>FXYD6</a></td><td>FXYD6</td><td>2737</td><td>0.216</td><td>0.1505</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=DLL3'>DLL3</a></td><td>DLL3</td><td>2822</td><td>0.204</td><td>0.1948</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=NEU4'>NEU4</a></td><td>NEU4</td><td>3313</td><td>0.158</td><td>0.2118</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=BTG2'>BTG2</a></td><td>BTG2</td><td>3497</td><td>0.141</td><td>0.2372</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=LRRN1'>LRRN1</a></td><td>LRRN1</td><td>3503</td><td>0.140</td><td>0.2699</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=TSPAN13'>TSPAN13</a></td><td>TSPAN13</td><td>3558</td><td>0.136</td><td>0.2995</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=SEZ6'>SEZ6</a></td><td>SEZ6</td><td>3567</td><td>0.135</td><td>0.3310</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=TUBB3'>TUBB3</a></td><td>TUBB3</td><td>3898</td><td>0.116</td><td>0.3445</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=TAGLN3'>TAGLN3</a></td><td>TAGLN3</td><td>3972</td><td>0.112</td><td>0.3678</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=DLL1'>DLL1</a></td><td>DLL1</td><td>3982</td><td>0.112</td><td>0.3936</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=SHD'>SHD</a></td><td>SHD</td><td>4071</td><td>0.108</td><td>0.4153</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=SOX4'>SOX4</a></td><td>SOX4</td><td>4269</td><td>0.100</td><td>0.4306</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=OLIG1'>OLIG1</a></td><td>OLIG1</td><td>4434</td><td>0.092</td><td>0.4453</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=SERINC5'>SERINC5</a></td><td>SERINC5</td><td>4611</td><td>0.084</td><td>0.4577</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=TUBA1A'>TUBA1A</a></td><td>TUBA1A</td><td>4671</td><td>0.082</td><td>0.4745</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=MLLT11'>MLLT11</a></td><td>MLLT11</td><td>4717</td><td>0.081</td><td>0.4915</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=CHD7'>CHD7</a></td><td>CHD7</td><td>5075</td><td>0.070</td><td>0.4933</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=PFN2'>PFN2</a></td><td>PFN2</td><td>5122</td><td>0.069</td><td>0.5076</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=HN1'>HN1</a></td><td>HN1</td><td>5391</td><td>0.062</td><td>0.5112</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=ASCL1'>ASCL1</a></td><td>ASCL1</td><td>5543</td><td>0.059</td><td>0.5188</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=ELAVL4'>ELAVL4</a></td><td>ELAVL4</td><td>5801</td><td>0.054</td><td>0.5209</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=DBN1'>DBN1</a></td><td>DBN1</td><td>5806</td><td>0.054</td><td>0.5334</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=GRIK2'>GRIK2</a></td><td>GRIK2</td><td>5874</td><td>0.053</td><td>0.5430</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=SEZ6L'>SEZ6L</a></td><td>SEZ6L</td><td>5910</td><td>0.052</td><td>0.5537</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=STMN1'>STMN1</a></td><td>STMN1</td><td>6116</td><td>0.049</td><td>0.5567</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=MAP2'>MAP2</a></td><td>MAP2</td><td>6412</td><td>0.044</td><td>0.5548</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=SOX11'>SOX11</a></td><td>SOX11</td><td>6421</td><td>0.044</td><td>0.5647</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=HES6'>HES6</a></td><td>HES6</td><td>6813</td><td>0.038</td><td>0.5575</td><td>No</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=MEST'>MEST</a></td><td>MEST</td><td>7061</td><td>0.035</td><td>0.5555</td><td>No</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=MARCKSL1'>MARCKSL1</a></td><td>MARCKSL1</td><td>7231</td><td>0.033</td><td>0.5563</td><td>No</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=PTPRS'>PTPRS</a></td><td>PTPRS</td><td>7371</td><td>0.031</td><td>0.5578</td><td>No</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=LMF1'>LMF1</a></td><td>LMF1</td><td>7824</td><td>0.026</td><td>0.5453</td><td>No</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=BCAN'>BCAN</a></td><td>BCAN</td><td>7937</td><td>0.025</td><td>0.5465</td><td>No</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=ABAT'>ABAT</a></td><td>ABAT</td><td>8586</td><td>0.018</td><td>0.5241</td><td>No</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=GLCCI1'>GLCCI1</a></td><td>GLCCI1</td><td>8836</td><td>0.016</td><td>0.5175</td><td>No</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=BEX1'>BEX1</a></td><td>BEX1</td><td>9845</td><td>0.007</td><td>0.4777</td><td>No</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=NPPA'>NPPA</a></td><td>NPPA</td><td>11467</td><td>0.000</td><td>0.4111</td><td>No</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=PCBP4'>PCBP4</a></td><td>PCBP4</td><td>15628</td><td>-0.007</td><td>0.2418</td><td>No</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=HIP1'>HIP1</a></td><td>HIP1</td><td>16321</td><td>-0.014</td><td>0.2166</td><td>No</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=AMOTL2'>AMOTL2</a></td><td>AMOTL2</td><td>16968</td><td>-0.021</td><td>0.1949</td><td>No</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=TCF12'>TCF12</a></td><td>TCF12</td><td>17083</td><td>-0.022</td><td>0.1954</td><td>No</td></tr><tr><td class='lessen'>45</td><td><a href='https://ensembl.org/Search/Results?q=ELMO1'>ELMO1</a></td><td>ELMO1</td><td>19587</td><td>-0.075</td><td>0.1101</td><td>No</td></tr><tr><td class='lessen'>46</td><td><a href='https://ensembl.org/Search/Results?q=ETV1'>ETV1</a></td><td>ETV1</td><td>20337</td><td>-0.109</td><td>0.1048</td><td>No</td></tr><tr><td class='lessen'>47</td><td><a href='https://ensembl.org/Search/Results?q=SCG3'>SCG3</a></td><td>SCG3</td><td>20572</td><td>-0.121</td><td>0.1234</td><td>No</td></tr><tr><td class='lessen'>48</td><td><a href='https://ensembl.org/Search/Results?q=DCX'>DCX</a></td><td>DCX</td><td>20918</td><td>-0.142</td><td>0.1426</td><td>No</td></tr><caption class='table'>Table: GSEA details <a href='NEFTEL_NPC1_2019.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='NEFTEL_NPC1_2019' src='NEFTEL_NPC1_2019_190.png'><br><br><caption>Fig 2: NEFTEL_NPC1_2019    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_191.png'><br><br><caption>Fig 3: NEFTEL_NPC1_2019: Random ES distribution    <br> Gene set null distribution of ES for <b>NEFTEL_NPC1_2019</b></caption></div><br></body></html>