<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set NEFTEL_NPC2_2019[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>NSCs_shNf1_sgFosl1.NSCs_shNf1_sgFosl1.cls<br>#Fosl1_versus_Ctrl.NSCs_shNf1_sgFosl1.cls<br>#Fosl1_versus_Ctrl_repos</td></tr><tr><td>Phenotype</td><td>NSCs_shNf1_sgFosl1.cls#Fosl1_versus_Ctrl_repos</td></tr><tr><td>Upregulated in class</td><td>Ctrl</td></tr><tr><td>GeneSet</td><td>NEFTEL_NPC2_2019</td></tr><tr><td>Enrichment Score (ES)</td><td>-0.54730195</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>-1.7339267</td></tr><tr><td>Nominal p-value</td><td>0.007827789</td></tr><tr><td>FDR q-value</td><td>0.018443286</td></tr><tr><td>FWER p-Value</td><td>0.015</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_NEFTEL_NPC2_2019' src='enplot_NEFTEL_NPC2_2019_216.png'><br><br><caption>Fig 1: Enrichment plot: NEFTEL_NPC2_2019    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=IGFBPL1'>IGFBPL1</a></td><td>IGFBPL1</td><td>1248</td><td>0.342</td><td>-0.0049</td><td>No</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=SNAP25'>SNAP25</a></td><td>SNAP25</td><td>1348</td><td>0.316</td><td>0.0339</td><td>No</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=MIAT'>MIAT</a></td><td>MIAT</td><td>1531</td><td>0.282</td><td>0.0647</td><td>No</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=CD200'>CD200</a></td><td>CD200</td><td>3561</td><td>0.136</td><td>-0.0002</td><td>No</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=NSG1'>NSG1</a></td><td>NSG1</td><td>3822</td><td>0.119</td><td>0.0053</td><td>No</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=TUBB3'>TUBB3</a></td><td>TUBB3</td><td>3898</td><td>0.116</td><td>0.0179</td><td>No</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=TAGLN3'>TAGLN3</a></td><td>TAGLN3</td><td>3972</td><td>0.112</td><td>0.0302</td><td>No</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=SOX4'>SOX4</a></td><td>SOX4</td><td>4269</td><td>0.100</td><td>0.0315</td><td>No</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=MLLT11'>MLLT11</a></td><td>MLLT11</td><td>4717</td><td>0.081</td><td>0.0241</td><td>No</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=DLX5'>DLX5</a></td><td>DLX5</td><td>5107</td><td>0.069</td><td>0.0175</td><td>No</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=ATP1B1'>ATP1B1</a></td><td>ATP1B1</td><td>5133</td><td>0.069</td><td>0.0258</td><td>No</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=HN1'>HN1</a></td><td>HN1</td><td>5391</td><td>0.062</td><td>0.0237</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=LBH'>LBH</a></td><td>LBH</td><td>5565</td><td>0.059</td><td>0.0246</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=ELAVL4'>ELAVL4</a></td><td>ELAVL4</td><td>5801</td><td>0.054</td><td>0.0222</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=DBN1'>DBN1</a></td><td>DBN1</td><td>5806</td><td>0.054</td><td>0.0294</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=STMN1'>STMN1</a></td><td>STMN1</td><td>6116</td><td>0.049</td><td>0.0233</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=SOX11'>SOX11</a></td><td>SOX11</td><td>6421</td><td>0.044</td><td>0.0167</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=SEPT3'>SEPT3</a></td><td>SEPT3</td><td>6569</td><td>0.041</td><td>0.0163</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=TUBB2A'>TUBB2A</a></td><td>TUBB2A</td><td>6776</td><td>0.038</td><td>0.0131</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=ENO2'>ENO2</a></td><td>ENO2</td><td>6922</td><td>0.036</td><td>0.0120</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=NREP'>NREP</a></td><td>NREP</td><td>6946</td><td>0.036</td><td>0.0160</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=NDRG4'>NDRG4</a></td><td>NDRG4</td><td>7086</td><td>0.034</td><td>0.0150</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=TCF4'>TCF4</a></td><td>TCF4</td><td>8169</td><td>0.022</td><td>-0.0265</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=PKIA'>PKIA</a></td><td>PKIA</td><td>8235</td><td>0.021</td><td>-0.0263</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=STMN4'>STMN4</a></td><td>STMN4</td><td>8543</td><td>0.018</td><td>-0.0364</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=DDAH2'>DDAH2</a></td><td>DDAH2</td><td>8611</td><td>0.018</td><td>-0.0367</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=MAP1B'>MAP1B</a></td><td>MAP1B</td><td>8864</td><td>0.015</td><td>-0.0450</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=UCHL1'>UCHL1</a></td><td>UCHL1</td><td>9174</td><td>0.013</td><td>-0.0560</td><td>No</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=FNBP1L'>FNBP1L</a></td><td>FNBP1L</td><td>14890</td><td>-0.000</td><td>-0.2907</td><td>No</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=CEP170'>CEP170</a></td><td>CEP170</td><td>15746</td><td>-0.008</td><td>-0.3247</td><td>No</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=NFIX'>NFIX</a></td><td>NFIX</td><td>15771</td><td>-0.008</td><td>-0.3245</td><td>No</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=DPYSL5'>DPYSL5</a></td><td>DPYSL5</td><td>16753</td><td>-0.018</td><td>-0.3623</td><td>No</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=PAK3'>PAK3</a></td><td>PAK3</td><td>16903</td><td>-0.020</td><td>-0.3658</td><td>No</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=KIF5A'>KIF5A</a></td><td>KIF5A</td><td>17402</td><td>-0.026</td><td>-0.3827</td><td>No</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=BLCAP'>BLCAP</a></td><td>BLCAP</td><td>18049</td><td>-0.035</td><td>-0.4044</td><td>No</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=NFIB'>NFIB</a></td><td>NFIB</td><td>18069</td><td>-0.036</td><td>-0.4004</td><td>No</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=DPYSL3'>DPYSL3</a></td><td>DPYSL3</td><td>19025</td><td>-0.056</td><td>-0.4321</td><td>No</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=RBFOX2'>RBFOX2</a></td><td>RBFOX2</td><td>19768</td><td>-0.083</td><td>-0.4513</td><td>No</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=KIF5C'>KIF5C</a></td><td>KIF5C</td><td>20382</td><td>-0.111</td><td>-0.4614</td><td>No</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=DCX'>DCX</a></td><td>DCX</td><td>20918</td><td>-0.142</td><td>-0.4641</td><td>No</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=RND3'>RND3</a></td><td>RND3</td><td>21020</td><td>-0.154</td><td>-0.4474</td><td>No</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=GNG3'>GNG3</a></td><td>GNG3</td><td>23454</td><td>-0.469</td><td>-0.4837</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=DYNC1I1'>DYNC1I1</a></td><td>DYNC1I1</td><td>23550</td><td>-0.503</td><td>-0.4193</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=CRABP1'>CRABP1</a></td><td>CRABP1</td><td>24274</td><td>-1.277</td><td>-0.2758</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>45</td><td><a href='https://ensembl.org/Search/Results?q=STMN2'>STMN2</a></td><td>STMN2</td><td>24377</td><td>-2.068</td><td>0.0005</td><td bgcolor='#CCFFCC'>Yes</td></tr><caption class='table'>Table: GSEA details <a href='NEFTEL_NPC2_2019.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='NEFTEL_NPC2_2019' src='NEFTEL_NPC2_2019_217.png'><br><br><caption>Fig 2: NEFTEL_NPC2_2019    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_218.png'><br><br><caption>Fig 3: NEFTEL_NPC2_2019: Random ES distribution    <br> Gene set null distribution of ES for <b>NEFTEL_NPC2_2019</b></caption></div><br></body></html>