<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set NEFTEL_OPC_2019[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>NSCs_shNf1_sgFosl1.NSCs_shNf1_sgFosl1.cls<br>#Fosl1_versus_Ctrl.NSCs_shNf1_sgFosl1.cls<br>#Fosl1_versus_Ctrl_repos</td></tr><tr><td>Phenotype</td><td>NSCs_shNf1_sgFosl1.cls#Fosl1_versus_Ctrl_repos</td></tr><tr><td>Upregulated in class</td><td>Fosl1</td></tr><tr><td>GeneSet</td><td>NEFTEL_OPC_2019</td></tr><tr><td>Enrichment Score (ES)</td><td>0.43013</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>1.1311173</td></tr><tr><td>Nominal p-value</td><td>0.30645162</td></tr><tr><td>FDR q-value</td><td>0.62415665</td></tr><tr><td>FWER p-Value</td><td>0.959</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_NEFTEL_OPC_2019' src='enplot_NEFTEL_OPC_2019_198.png'><br><br><caption>Fig 1: Enrichment plot: NEFTEL_OPC_2019    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=PMP2'>PMP2</a></td><td>PMP2</td><td>154</td><td>0.771</td><td>0.0964</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=NKAIN4'>NKAIN4</a></td><td>NKAIN4</td><td>544</td><td>0.496</td><td>0.1464</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=OMG'>OMG</a></td><td>OMG</td><td>598</td><td>0.473</td><td>0.2072</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=TNR'>TNR</a></td><td>TNR</td><td>1688</td><td>0.258</td><td>0.1968</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=FGF12'>FGF12</a></td><td>FGF12</td><td>2037</td><td>0.249</td><td>0.2157</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=LHFPL3'>LHFPL3</a></td><td>LHFPL3</td><td>2627</td><td>0.232</td><td>0.2224</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=FXYD6'>FXYD6</a></td><td>FXYD6</td><td>2737</td><td>0.216</td><td>0.2466</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=NLGN3'>NLGN3</a></td><td>NLGN3</td><td>2890</td><td>0.197</td><td>0.2666</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=PLLP'>PLLP</a></td><td>PLLP</td><td>3009</td><td>0.184</td><td>0.2863</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=ALCAM'>ALCAM</a></td><td>ALCAM</td><td>3045</td><td>0.181</td><td>0.3089</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=GPR37L1'>GPR37L1</a></td><td>GPR37L1</td><td>3111</td><td>0.175</td><td>0.3295</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=THY1'>THY1</a></td><td>THY1</td><td>3146</td><td>0.171</td><td>0.3509</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=SCRG1'>SCRG1</a></td><td>SCRG1</td><td>3156</td><td>0.170</td><td>0.3732</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=FABP5'>FABP5</a></td><td>FABP5</td><td>3300</td><td>0.159</td><td>0.3884</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=VCAN'>VCAN</a></td><td>VCAN</td><td>3309</td><td>0.158</td><td>0.4092</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=NEU4'>NEU4</a></td><td>NEU4</td><td>3313</td><td>0.158</td><td>0.4301</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=BCAS1'>BCAS1</a></td><td>BCAS1</td><td>3907</td><td>0.115</td><td>0.4211</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=CNTN1'>CNTN1</a></td><td>CNTN1</td><td>4306</td><td>0.098</td><td>0.4178</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=OLIG1'>OLIG1</a></td><td>OLIG1</td><td>4434</td><td>0.092</td><td>0.4248</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=SERINC5'>SERINC5</a></td><td>SERINC5</td><td>4611</td><td>0.084</td><td>0.4287</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=TMEM206'>TMEM206</a></td><td>TMEM206</td><td>5138</td><td>0.069</td><td>0.4162</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=RTKN'>RTKN</a></td><td>RTKN</td><td>5243</td><td>0.066</td><td>0.4208</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=PLP1'>PLP1</a></td><td>PLP1</td><td>5486</td><td>0.060</td><td>0.4188</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=CNP'>CNP</a></td><td>CNP</td><td>5625</td><td>0.057</td><td>0.4208</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=LIMA1'>LIMA1</a></td><td>LIMA1</td><td>5868</td><td>0.053</td><td>0.4179</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=DBI'>DBI</a></td><td>DBI</td><td>6266</td><td>0.046</td><td>0.4077</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=PGRMC1'>PGRMC1</a></td><td>PGRMC1</td><td>6964</td><td>0.036</td><td>0.3839</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=PHYHIPL'>PHYHIPL</a></td><td>PHYHIPL</td><td>7724</td><td>0.027</td><td>0.3563</td><td>No</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=LMF1'>LMF1</a></td><td>LMF1</td><td>7824</td><td>0.026</td><td>0.3557</td><td>No</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=BCAN'>BCAN</a></td><td>BCAN</td><td>7937</td><td>0.025</td><td>0.3543</td><td>No</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=PCDHGC3'>PCDHGC3</a></td><td>PCDHGC3</td><td>8624</td><td>0.018</td><td>0.3285</td><td>No</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=SIRT2'>SIRT2</a></td><td>SIRT2</td><td>9070</td><td>0.014</td><td>0.3120</td><td>No</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=CADM2'>CADM2</a></td><td>CADM2</td><td>9568</td><td>0.009</td><td>0.2928</td><td>No</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=PTPRZ1'>PTPRZ1</a></td><td>PTPRZ1</td><td>10361</td><td>0.002</td><td>0.2606</td><td>No</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=RNF13'>RNF13</a></td><td>RNF13</td><td>15654</td><td>-0.007</td><td>0.0442</td><td>No</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=GPM6B'>GPM6B</a></td><td>GPM6B</td><td>15681</td><td>-0.008</td><td>0.0441</td><td>No</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=GPR17'>GPR17</a></td><td>GPR17</td><td>17695</td><td>-0.030</td><td>-0.0346</td><td>No</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=PSAT1'>PSAT1</a></td><td>PSAT1</td><td>17892</td><td>-0.033</td><td>-0.0383</td><td>No</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=TNS3'>TNS3</a></td><td>TNS3</td><td>18333</td><td>-0.040</td><td>-0.0510</td><td>No</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=P2RX7'>P2RX7</a></td><td>P2RX7</td><td>18631</td><td>-0.046</td><td>-0.0570</td><td>No</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=RAB31'>RAB31</a></td><td>RAB31</td><td>19332</td><td>-0.066</td><td>-0.0770</td><td>No</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=TTYH1'>TTYH1</a></td><td>TTYH1</td><td>19522</td><td>-0.072</td><td>-0.0751</td><td>No</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=LPPR1'>LPPR1</a></td><td>LPPR1</td><td>20919</td><td>-0.142</td><td>-0.1135</td><td>No</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=FIBIN'>FIBIN</a></td><td>FIBIN</td><td>21496</td><td>-0.203</td><td>-0.1101</td><td>No</td></tr><tr><td class='lessen'>45</td><td><a href='https://ensembl.org/Search/Results?q=APOD'>APOD</a></td><td>APOD</td><td>24051</td><td>-0.796</td><td>-0.1090</td><td>No</td></tr><tr><td class='lessen'>46</td><td><a href='https://ensembl.org/Search/Results?q=HRASLS'>HRASLS</a></td><td>HRASLS</td><td>24130</td><td>-0.922</td><td>0.0106</td><td>No</td></tr><caption class='table'>Table: GSEA details <a href='NEFTEL_OPC_2019.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='NEFTEL_OPC_2019' src='NEFTEL_OPC_2019_199.png'><br><br><caption>Fig 2: NEFTEL_OPC_2019    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_200.png'><br><br><caption>Fig 3: NEFTEL_OPC_2019: Random ES distribution    <br> Gene set null distribution of ES for <b>NEFTEL_OPC_2019</b></caption></div><br></body></html>