<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set POU3F3_REGULON[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>NSCs_shNf1_sgFosl1.NSCs_shNf1_sgFosl1.cls<br>#Fosl1_versus_Ctrl.NSCs_shNf1_sgFosl1.cls<br>#Fosl1_versus_Ctrl_repos</td></tr><tr><td>Phenotype</td><td>NSCs_shNf1_sgFosl1.cls#Fosl1_versus_Ctrl_repos</td></tr><tr><td>Upregulated in class</td><td>Ctrl</td></tr><tr><td>GeneSet</td><td>POU3F3_REGULON</td></tr><tr><td>Enrichment Score (ES)</td><td>-0.505826</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>-1.6746476</td></tr><tr><td>Nominal p-value</td><td>0.0</td></tr><tr><td>FDR q-value</td><td>0.013277199</td></tr><tr><td>FWER p-Value</td><td>0.022</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_POU3F3_REGULON' src='enplot_POU3F3_REGULON_219.png'><br><br><caption>Fig 1: Enrichment plot: POU3F3_REGULON    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=ADD2'>ADD2</a></td><td>ADD2</td><td>1620</td><td>0.268</td><td>-0.0398</td><td>No</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=P2RY1'>P2RY1</a></td><td>P2RY1</td><td>2806</td><td>0.206</td><td>-0.0679</td><td>No</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=PIK3C2B'>PIK3C2B</a></td><td>PIK3C2B</td><td>3165</td><td>0.169</td><td>-0.0656</td><td>No</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=STMN3'>STMN3</a></td><td>STMN3</td><td>3187</td><td>0.168</td><td>-0.0496</td><td>No</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=CACNG4'>CACNG4</a></td><td>CACNG4</td><td>3254</td><td>0.162</td><td>-0.0361</td><td>No</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=EFR3B'>EFR3B</a></td><td>EFR3B</td><td>3358</td><td>0.154</td><td>-0.0248</td><td>No</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=NSL1'>NSL1</a></td><td>NSL1</td><td>4628</td><td>0.083</td><td>-0.0687</td><td>No</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=PDE4B'>PDE4B</a></td><td>PDE4B</td><td>4637</td><td>0.083</td><td>-0.0607</td><td>No</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=TUBA1A'>TUBA1A</a></td><td>TUBA1A</td><td>4671</td><td>0.082</td><td>-0.0538</td><td>No</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=MEIS2'>MEIS2</a></td><td>MEIS2</td><td>4936</td><td>0.074</td><td>-0.0572</td><td>No</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=TMEM123'>TMEM123</a></td><td>TMEM123</td><td>4964</td><td>0.073</td><td>-0.0510</td><td>No</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=KLHL25'>KLHL25</a></td><td>KLHL25</td><td>5271</td><td>0.065</td><td>-0.0570</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=ING4'>ING4</a></td><td>ING4</td><td>5308</td><td>0.064</td><td>-0.0521</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=NCALD'>NCALD</a></td><td>NCALD</td><td>5373</td><td>0.063</td><td>-0.0484</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=KCNA2'>KCNA2</a></td><td>KCNA2</td><td>5971</td><td>0.051</td><td>-0.0678</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=GAS1'>GAS1</a></td><td>GAS1</td><td>6287</td><td>0.046</td><td>-0.0762</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=SV2A'>SV2A</a></td><td>SV2A</td><td>6410</td><td>0.044</td><td>-0.0768</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=CDH4'>CDH4</a></td><td>CDH4</td><td>6583</td><td>0.041</td><td>-0.0798</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=TNIP1'>TNIP1</a></td><td>TNIP1</td><td>6598</td><td>0.041</td><td>-0.0762</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=DZIP3'>DZIP3</a></td><td>DZIP3</td><td>7098</td><td>0.034</td><td>-0.0933</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=ZKSCAN3'>ZKSCAN3</a></td><td>ZKSCAN3</td><td>7223</td><td>0.033</td><td>-0.0951</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=PURG'>PURG</a></td><td>PURG</td><td>7423</td><td>0.030</td><td>-0.1003</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=VPS72'>VPS72</a></td><td>VPS72</td><td>7454</td><td>0.030</td><td>-0.0985</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=IBTK'>IBTK</a></td><td>IBTK</td><td>7487</td><td>0.030</td><td>-0.0968</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=FABP7'>FABP7</a></td><td>FABP7</td><td>7789</td><td>0.026</td><td>-0.1065</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=ELOVL5'>ELOVL5</a></td><td>ELOVL5</td><td>8157</td><td>0.022</td><td>-0.1194</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=SALL1'>SALL1</a></td><td>SALL1</td><td>8184</td><td>0.022</td><td>-0.1183</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=GPRC5B'>GPRC5B</a></td><td>GPRC5B</td><td>8329</td><td>0.020</td><td>-0.1222</td><td>No</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=TMCO1'>TMCO1</a></td><td>TMCO1</td><td>8361</td><td>0.020</td><td>-0.1215</td><td>No</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=LPIN1'>LPIN1</a></td><td>LPIN1</td><td>8537</td><td>0.018</td><td>-0.1268</td><td>No</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=KLF12'>KLF12</a></td><td>KLF12</td><td>9262</td><td>0.012</td><td>-0.1554</td><td>No</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=DNMT3A'>DNMT3A</a></td><td>DNMT3A</td><td>9277</td><td>0.012</td><td>-0.1548</td><td>No</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=SRPK2'>SRPK2</a></td><td>SRPK2</td><td>9480</td><td>0.010</td><td>-0.1621</td><td>No</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=DUSP11'>DUSP11</a></td><td>DUSP11</td><td>14883</td><td>-0.000</td><td>-0.3844</td><td>No</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=PCDH9'>PCDH9</a></td><td>PCDH9</td><td>14905</td><td>-0.001</td><td>-0.3852</td><td>No</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=HP1BP3'>HP1BP3</a></td><td>HP1BP3</td><td>14911</td><td>-0.001</td><td>-0.3853</td><td>No</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=CRTC1'>CRTC1</a></td><td>CRTC1</td><td>14997</td><td>-0.002</td><td>-0.3887</td><td>No</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=SCP2'>SCP2</a></td><td>SCP2</td><td>15035</td><td>-0.002</td><td>-0.3900</td><td>No</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=GOLPH3'>GOLPH3</a></td><td>GOLPH3</td><td>15455</td><td>-0.005</td><td>-0.4067</td><td>No</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=HPS5'>HPS5</a></td><td>HPS5</td><td>15470</td><td>-0.006</td><td>-0.4067</td><td>No</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=CACNB2'>CACNB2</a></td><td>CACNB2</td><td>15833</td><td>-0.009</td><td>-0.4207</td><td>No</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=SSBP2'>SSBP2</a></td><td>SSBP2</td><td>15933</td><td>-0.010</td><td>-0.4238</td><td>No</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=LUZP1'>LUZP1</a></td><td>LUZP1</td><td>16235</td><td>-0.013</td><td>-0.4349</td><td>No</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=ERI3'>ERI3</a></td><td>ERI3</td><td>16242</td><td>-0.013</td><td>-0.4338</td><td>No</td></tr><tr><td class='lessen'>45</td><td><a href='https://ensembl.org/Search/Results?q=UTP6'>UTP6</a></td><td>UTP6</td><td>16299</td><td>-0.014</td><td>-0.4348</td><td>No</td></tr><tr><td class='lessen'>46</td><td><a href='https://ensembl.org/Search/Results?q=HIP1'>HIP1</a></td><td>HIP1</td><td>16321</td><td>-0.014</td><td>-0.4342</td><td>No</td></tr><tr><td class='lessen'>47</td><td><a href='https://ensembl.org/Search/Results?q=UTY'>UTY</a></td><td>UTY</td><td>16323</td><td>-0.014</td><td>-0.4329</td><td>No</td></tr><tr><td class='lessen'>48</td><td><a href='https://ensembl.org/Search/Results?q=PSD3'>PSD3</a></td><td>PSD3</td><td>16397</td><td>-0.015</td><td>-0.4344</td><td>No</td></tr><tr><td class='lessen'>49</td><td><a href='https://ensembl.org/Search/Results?q=EXTL3'>EXTL3</a></td><td>EXTL3</td><td>16675</td><td>-0.017</td><td>-0.4441</td><td>No</td></tr><tr><td class='lessen'>50</td><td><a href='https://ensembl.org/Search/Results?q=RAB11FIP2'>RAB11FIP2</a></td><td>RAB11FIP2</td><td>16790</td><td>-0.019</td><td>-0.4469</td><td>No</td></tr><tr><td class='lessen'>51</td><td><a href='https://ensembl.org/Search/Results?q=RNMT'>RNMT</a></td><td>RNMT</td><td>16833</td><td>-0.019</td><td>-0.4467</td><td>No</td></tr><tr><td class='lessen'>52</td><td><a href='https://ensembl.org/Search/Results?q=FZD3'>FZD3</a></td><td>FZD3</td><td>16912</td><td>-0.020</td><td>-0.4479</td><td>No</td></tr><tr><td class='lessen'>53</td><td><a href='https://ensembl.org/Search/Results?q=RFX4'>RFX4</a></td><td>RFX4</td><td>16970</td><td>-0.021</td><td>-0.4482</td><td>No</td></tr><tr><td class='lessen'>54</td><td><a href='https://ensembl.org/Search/Results?q=LRRFIP1'>LRRFIP1</a></td><td>LRRFIP1</td><td>17105</td><td>-0.022</td><td>-0.4515</td><td>No</td></tr><tr><td class='lessen'>55</td><td><a href='https://ensembl.org/Search/Results?q=ARL3'>ARL3</a></td><td>ARL3</td><td>17200</td><td>-0.024</td><td>-0.4530</td><td>No</td></tr><tr><td class='lessen'>56</td><td><a href='https://ensembl.org/Search/Results?q=PTCD3'>PTCD3</a></td><td>PTCD3</td><td>17275</td><td>-0.024</td><td>-0.4536</td><td>No</td></tr><tr><td class='lessen'>57</td><td><a href='https://ensembl.org/Search/Results?q=KIF1B'>KIF1B</a></td><td>KIF1B</td><td>17298</td><td>-0.025</td><td>-0.4520</td><td>No</td></tr><tr><td class='lessen'>58</td><td><a href='https://ensembl.org/Search/Results?q=ATF7IP'>ATF7IP</a></td><td>ATF7IP</td><td>17357</td><td>-0.025</td><td>-0.4518</td><td>No</td></tr><tr><td class='lessen'>59</td><td><a href='https://ensembl.org/Search/Results?q=TRIM37'>TRIM37</a></td><td>TRIM37</td><td>17373</td><td>-0.026</td><td>-0.4499</td><td>No</td></tr><tr><td class='lessen'>60</td><td><a href='https://ensembl.org/Search/Results?q=ATIC'>ATIC</a></td><td>ATIC</td><td>17456</td><td>-0.026</td><td>-0.4506</td><td>No</td></tr><tr><td class='lessen'>61</td><td><a href='https://ensembl.org/Search/Results?q=TLE1'>TLE1</a></td><td>TLE1</td><td>17472</td><td>-0.027</td><td>-0.4485</td><td>No</td></tr><tr><td class='lessen'>62</td><td><a href='https://ensembl.org/Search/Results?q=RGS12'>RGS12</a></td><td>RGS12</td><td>17685</td><td>-0.030</td><td>-0.4543</td><td>No</td></tr><tr><td class='lessen'>63</td><td><a href='https://ensembl.org/Search/Results?q=PBX1'>PBX1</a></td><td>PBX1</td><td>18242</td><td>-0.039</td><td>-0.4733</td><td>No</td></tr><tr><td class='lessen'>64</td><td><a href='https://ensembl.org/Search/Results?q=SPATA6'>SPATA6</a></td><td>SPATA6</td><td>18284</td><td>-0.040</td><td>-0.4710</td><td>No</td></tr><tr><td class='lessen'>65</td><td><a href='https://ensembl.org/Search/Results?q=TBPL1'>TBPL1</a></td><td>TBPL1</td><td>18304</td><td>-0.040</td><td>-0.4677</td><td>No</td></tr><tr><td class='lessen'>66</td><td><a href='https://ensembl.org/Search/Results?q=TEKT2'>TEKT2</a></td><td>TEKT2</td><td>18319</td><td>-0.040</td><td>-0.4643</td><td>No</td></tr><tr><td class='lessen'>67</td><td><a href='https://ensembl.org/Search/Results?q=CREG1'>CREG1</a></td><td>CREG1</td><td>18471</td><td>-0.043</td><td>-0.4662</td><td>No</td></tr><tr><td class='lessen'>68</td><td><a href='https://ensembl.org/Search/Results?q=TARS'>TARS</a></td><td>TARS</td><td>18609</td><td>-0.046</td><td>-0.4673</td><td>No</td></tr><tr><td class='lessen'>69</td><td><a href='https://ensembl.org/Search/Results?q=KANK1'>KANK1</a></td><td>KANK1</td><td>18786</td><td>-0.050</td><td>-0.4695</td><td>No</td></tr><tr><td class='lessen'>70</td><td><a href='https://ensembl.org/Search/Results?q=TRPM3'>TRPM3</a></td><td>TRPM3</td><td>18877</td><td>-0.052</td><td>-0.4680</td><td>No</td></tr><tr><td class='lessen'>71</td><td><a href='https://ensembl.org/Search/Results?q=GLUL'>GLUL</a></td><td>GLUL</td><td>18883</td><td>-0.052</td><td>-0.4630</td><td>No</td></tr><tr><td class='lessen'>72</td><td><a href='https://ensembl.org/Search/Results?q=SLC7A1'>SLC7A1</a></td><td>SLC7A1</td><td>19501</td><td>-0.072</td><td>-0.4811</td><td>No</td></tr><tr><td class='lessen'>73</td><td><a href='https://ensembl.org/Search/Results?q=TTYH1'>TTYH1</a></td><td>TTYH1</td><td>19522</td><td>-0.072</td><td>-0.4747</td><td>No</td></tr><tr><td class='lessen'>74</td><td><a href='https://ensembl.org/Search/Results?q=CACNG1'>CACNG1</a></td><td>CACNG1</td><td>19837</td><td>-0.086</td><td>-0.4790</td><td>No</td></tr><tr><td class='lessen'>75</td><td><a href='https://ensembl.org/Search/Results?q=FAM131B'>FAM131B</a></td><td>FAM131B</td><td>20375</td><td>-0.111</td><td>-0.4900</td><td>No</td></tr><tr><td class='lessen'>76</td><td><a href='https://ensembl.org/Search/Results?q=ACSL1'>ACSL1</a></td><td>ACSL1</td><td>20761</td><td>-0.131</td><td>-0.4926</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>77</td><td><a href='https://ensembl.org/Search/Results?q=BCL2L1'>BCL2L1</a></td><td>BCL2L1</td><td>20790</td><td>-0.133</td><td>-0.4804</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>78</td><td><a href='https://ensembl.org/Search/Results?q=MYO1C'>MYO1C</a></td><td>MYO1C</td><td>20897</td><td>-0.140</td><td>-0.4707</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>79</td><td><a href='https://ensembl.org/Search/Results?q=RFX2'>RFX2</a></td><td>RFX2</td><td>21002</td><td>-0.152</td><td>-0.4598</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>80</td><td><a href='https://ensembl.org/Search/Results?q=EHD4'>EHD4</a></td><td>EHD4</td><td>21067</td><td>-0.158</td><td>-0.4465</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>81</td><td><a href='https://ensembl.org/Search/Results?q=ABCD2'>ABCD2</a></td><td>ABCD2</td><td>21118</td><td>-0.163</td><td>-0.4322</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>82</td><td><a href='https://ensembl.org/Search/Results?q=RAI14'>RAI14</a></td><td>RAI14</td><td>22398</td><td>-0.340</td><td>-0.4507</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>83</td><td><a href='https://ensembl.org/Search/Results?q=DPP6'>DPP6</a></td><td>DPP6</td><td>23698</td><td>-0.572</td><td>-0.4468</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>84</td><td><a href='https://ensembl.org/Search/Results?q=CARD10'>CARD10</a></td><td>CARD10</td><td>23709</td><td>-0.581</td><td>-0.3889</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>85</td><td><a href='https://ensembl.org/Search/Results?q=FLRT1'>FLRT1</a></td><td>FLRT1</td><td>23731</td><td>-0.597</td><td>-0.3299</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>86</td><td><a href='https://ensembl.org/Search/Results?q=KLHDC8A'>KLHDC8A</a></td><td>KLHDC8A</td><td>24031</td><td>-0.764</td><td>-0.2655</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>87</td><td><a href='https://ensembl.org/Search/Results?q=FHL2'>FHL2</a></td><td>FHL2</td><td>24205</td><td>-1.090</td><td>-0.1633</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>88</td><td><a href='https://ensembl.org/Search/Results?q=FXYD5'>FXYD5</a></td><td>FXYD5</td><td>24345</td><td>-1.702</td><td>0.0018</td><td bgcolor='#CCFFCC'>Yes</td></tr><caption class='table'>Table: GSEA details <a href='POU3F3_REGULON.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='POU3F3_REGULON' src='POU3F3_REGULON_220.png'><br><br><caption>Fig 2: POU3F3_REGULON    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_221.png'><br><br><caption>Fig 3: POU3F3_REGULON: Random ES distribution    <br> Gene set null distribution of ES for <b>POU3F3_REGULON</b></caption></div><br></body></html>