<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set SALL2_REGULON[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>NSCs_shNf1_sgFosl1.NSCs_shNf1_sgFosl1.cls<br>#Fosl1_versus_Ctrl.NSCs_shNf1_sgFosl1.cls<br>#Fosl1_versus_Ctrl_repos</td></tr><tr><td>Phenotype</td><td>NSCs_shNf1_sgFosl1.cls#Fosl1_versus_Ctrl_repos</td></tr><tr><td>Upregulated in class</td><td>Ctrl</td></tr><tr><td>GeneSet</td><td>SALL2_REGULON</td></tr><tr><td>Enrichment Score (ES)</td><td>-0.31376374</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>-1.2332503</td></tr><tr><td>Nominal p-value</td><td>0.06042885</td></tr><tr><td>FDR q-value</td><td>0.26928315</td></tr><tr><td>FWER p-Value</td><td>0.838</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_SALL2_REGULON' src='enplot_SALL2_REGULON_255.png'><br><br><caption>Fig 1: Enrichment plot: SALL2_REGULON    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=IL17RB'>IL17RB</a></td><td>IL17RB</td><td>11</td><td>1.472</td><td>0.1154</td><td>No</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=ADAMTS3'>ADAMTS3</a></td><td>ADAMTS3</td><td>59</td><td>0.982</td><td>0.1908</td><td>No</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=CASP4'>CASP4</a></td><td>CASP4</td><td>204</td><td>0.693</td><td>0.2394</td><td>No</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=PAQR6'>PAQR6</a></td><td>PAQR6</td><td>1080</td><td>0.393</td><td>0.2343</td><td>No</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=GAL3ST4'>GAL3ST4</a></td><td>GAL3ST4</td><td>1303</td><td>0.328</td><td>0.2510</td><td>No</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=RPL39L'>RPL39L</a></td><td>RPL39L</td><td>2089</td><td>0.249</td><td>0.2383</td><td>No</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=NLGN3'>NLGN3</a></td><td>NLGN3</td><td>2890</td><td>0.197</td><td>0.2209</td><td>No</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=NOVA1'>NOVA1</a></td><td>NOVA1</td><td>3979</td><td>0.112</td><td>0.1849</td><td>No</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=NOTCH3'>NOTCH3</a></td><td>NOTCH3</td><td>4234</td><td>0.101</td><td>0.1824</td><td>No</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=SOX4'>SOX4</a></td><td>SOX4</td><td>4269</td><td>0.100</td><td>0.1889</td><td>No</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=ZFP30'>ZFP30</a></td><td>ZFP30</td><td>4276</td><td>0.099</td><td>0.1964</td><td>No</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=DHTKD1'>DHTKD1</a></td><td>DHTKD1</td><td>4378</td><td>0.094</td><td>0.1997</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=TBC1D8B'>TBC1D8B</a></td><td>TBC1D8B</td><td>4596</td><td>0.084</td><td>0.1974</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=PTGS2'>PTGS2</a></td><td>PTGS2</td><td>4602</td><td>0.084</td><td>0.2038</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=VASH1'>VASH1</a></td><td>VASH1</td><td>4636</td><td>0.083</td><td>0.2090</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=RAB8B'>RAB8B</a></td><td>RAB8B</td><td>4751</td><td>0.080</td><td>0.2106</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=ACSBG1'>ACSBG1</a></td><td>ACSBG1</td><td>5032</td><td>0.072</td><td>0.2047</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=SNX7'>SNX7</a></td><td>SNX7</td><td>5046</td><td>0.071</td><td>0.2098</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=CHD7'>CHD7</a></td><td>CHD7</td><td>5075</td><td>0.070</td><td>0.2142</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=ASCL1'>ASCL1</a></td><td>ASCL1</td><td>5543</td><td>0.059</td><td>0.1996</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=RASSF2'>RASSF2</a></td><td>RASSF2</td><td>5555</td><td>0.059</td><td>0.2038</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=FLRT3'>FLRT3</a></td><td>FLRT3</td><td>5641</td><td>0.057</td><td>0.2048</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=CTNND2'>CTNND2</a></td><td>CTNND2</td><td>5701</td><td>0.056</td><td>0.2068</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=RNFT2'>RNFT2</a></td><td>RNFT2</td><td>6045</td><td>0.050</td><td>0.1966</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=DTX3'>DTX3</a></td><td>DTX3</td><td>6222</td><td>0.047</td><td>0.1930</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=APBA2'>APBA2</a></td><td>APBA2</td><td>6300</td><td>0.046</td><td>0.1935</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=MAP2'>MAP2</a></td><td>MAP2</td><td>6412</td><td>0.044</td><td>0.1923</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=ENPP1'>ENPP1</a></td><td>ENPP1</td><td>6438</td><td>0.043</td><td>0.1947</td><td>No</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=CHD8'>CHD8</a></td><td>CHD8</td><td>6646</td><td>0.040</td><td>0.1894</td><td>No</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=MYLK'>MYLK</a></td><td>MYLK</td><td>6812</td><td>0.038</td><td>0.1856</td><td>No</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=GLRX2'>GLRX2</a></td><td>GLRX2</td><td>6843</td><td>0.038</td><td>0.1873</td><td>No</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=NTAN1'>NTAN1</a></td><td>NTAN1</td><td>7079</td><td>0.035</td><td>0.1803</td><td>No</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=MARCKSL1'>MARCKSL1</a></td><td>MARCKSL1</td><td>7231</td><td>0.033</td><td>0.1767</td><td>No</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=SLC22A17'>SLC22A17</a></td><td>SLC22A17</td><td>7520</td><td>0.029</td><td>0.1672</td><td>No</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=EVL'>EVL</a></td><td>EVL</td><td>7611</td><td>0.028</td><td>0.1657</td><td>No</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=ZMYM2'>ZMYM2</a></td><td>ZMYM2</td><td>7623</td><td>0.028</td><td>0.1674</td><td>No</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=RIN2'>RIN2</a></td><td>RIN2</td><td>7678</td><td>0.027</td><td>0.1673</td><td>No</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=ATP1B2'>ATP1B2</a></td><td>ATP1B2</td><td>7802</td><td>0.026</td><td>0.1643</td><td>No</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=NPAS3'>NPAS3</a></td><td>NPAS3</td><td>7884</td><td>0.025</td><td>0.1630</td><td>No</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=AGPAT5'>AGPAT5</a></td><td>AGPAT5</td><td>8726</td><td>0.017</td><td>0.1297</td><td>No</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=NCAN'>NCAN</a></td><td>NCAN</td><td>9540</td><td>0.010</td><td>0.0970</td><td>No</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=MSI1'>MSI1</a></td><td>MSI1</td><td>9548</td><td>0.009</td><td>0.0974</td><td>No</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=DENND5A'>DENND5A</a></td><td>DENND5A</td><td>9823</td><td>0.007</td><td>0.0867</td><td>No</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=SEC61A2'>SEC61A2</a></td><td>SEC61A2</td><td>10161</td><td>0.004</td><td>0.0732</td><td>No</td></tr><tr><td class='lessen'>45</td><td><a href='https://ensembl.org/Search/Results?q=PLXNA2'>PLXNA2</a></td><td>PLXNA2</td><td>10225</td><td>0.003</td><td>0.0708</td><td>No</td></tr><tr><td class='lessen'>46</td><td><a href='https://ensembl.org/Search/Results?q=KIF2A'>KIF2A</a></td><td>KIF2A</td><td>10307</td><td>0.003</td><td>0.0677</td><td>No</td></tr><tr><td class='lessen'>47</td><td><a href='https://ensembl.org/Search/Results?q=JAM2'>JAM2</a></td><td>JAM2</td><td>10381</td><td>0.002</td><td>0.0649</td><td>No</td></tr><tr><td class='lessen'>48</td><td><a href='https://ensembl.org/Search/Results?q=STARD7'>STARD7</a></td><td>STARD7</td><td>10450</td><td>0.002</td><td>0.0622</td><td>No</td></tr><tr><td class='lessen'>49</td><td><a href='https://ensembl.org/Search/Results?q=SEMA6A'>SEMA6A</a></td><td>SEMA6A</td><td>14984</td><td>-0.001</td><td>-0.1242</td><td>No</td></tr><tr><td class='lessen'>50</td><td><a href='https://ensembl.org/Search/Results?q=ARNT2'>ARNT2</a></td><td>ARNT2</td><td>15571</td><td>-0.006</td><td>-0.1478</td><td>No</td></tr><tr><td class='lessen'>51</td><td><a href='https://ensembl.org/Search/Results?q=PHLPP1'>PHLPP1</a></td><td>PHLPP1</td><td>15580</td><td>-0.006</td><td>-0.1476</td><td>No</td></tr><tr><td class='lessen'>52</td><td><a href='https://ensembl.org/Search/Results?q=COPB2'>COPB2</a></td><td>COPB2</td><td>15582</td><td>-0.007</td><td>-0.1472</td><td>No</td></tr><tr><td class='lessen'>53</td><td><a href='https://ensembl.org/Search/Results?q=ARPC1B'>ARPC1B</a></td><td>ARPC1B</td><td>15616</td><td>-0.007</td><td>-0.1480</td><td>No</td></tr><tr><td class='lessen'>54</td><td><a href='https://ensembl.org/Search/Results?q=PDCD6IP'>PDCD6IP</a></td><td>PDCD6IP</td><td>15840</td><td>-0.009</td><td>-0.1565</td><td>No</td></tr><tr><td class='lessen'>55</td><td><a href='https://ensembl.org/Search/Results?q=TRIM24'>TRIM24</a></td><td>TRIM24</td><td>15878</td><td>-0.009</td><td>-0.1572</td><td>No</td></tr><tr><td class='lessen'>56</td><td><a href='https://ensembl.org/Search/Results?q=PCM1'>PCM1</a></td><td>PCM1</td><td>15895</td><td>-0.009</td><td>-0.1572</td><td>No</td></tr><tr><td class='lessen'>57</td><td><a href='https://ensembl.org/Search/Results?q=LLGL1'>LLGL1</a></td><td>LLGL1</td><td>16300</td><td>-0.014</td><td>-0.1727</td><td>No</td></tr><tr><td class='lessen'>58</td><td><a href='https://ensembl.org/Search/Results?q=MEF2D'>MEF2D</a></td><td>MEF2D</td><td>16686</td><td>-0.017</td><td>-0.1872</td><td>No</td></tr><tr><td class='lessen'>59</td><td><a href='https://ensembl.org/Search/Results?q=DICER1'>DICER1</a></td><td>DICER1</td><td>16887</td><td>-0.020</td><td>-0.1939</td><td>No</td></tr><tr><td class='lessen'>60</td><td><a href='https://ensembl.org/Search/Results?q=FZD3'>FZD3</a></td><td>FZD3</td><td>16912</td><td>-0.020</td><td>-0.1933</td><td>No</td></tr><tr><td class='lessen'>61</td><td><a href='https://ensembl.org/Search/Results?q=CKB'>CKB</a></td><td>CKB</td><td>17128</td><td>-0.023</td><td>-0.2003</td><td>No</td></tr><tr><td class='lessen'>62</td><td><a href='https://ensembl.org/Search/Results?q=KIF1B'>KIF1B</a></td><td>KIF1B</td><td>17298</td><td>-0.025</td><td>-0.2054</td><td>No</td></tr><tr><td class='lessen'>63</td><td><a href='https://ensembl.org/Search/Results?q=MED8'>MED8</a></td><td>MED8</td><td>17677</td><td>-0.030</td><td>-0.2186</td><td>No</td></tr><tr><td class='lessen'>64</td><td><a href='https://ensembl.org/Search/Results?q=AGRN'>AGRN</a></td><td>AGRN</td><td>17795</td><td>-0.031</td><td>-0.2209</td><td>No</td></tr><tr><td class='lessen'>65</td><td><a href='https://ensembl.org/Search/Results?q=TRAPPC3'>TRAPPC3</a></td><td>TRAPPC3</td><td>17832</td><td>-0.032</td><td>-0.2199</td><td>No</td></tr><tr><td class='lessen'>66</td><td><a href='https://ensembl.org/Search/Results?q=YKT6'>YKT6</a></td><td>YKT6</td><td>18042</td><td>-0.035</td><td>-0.2257</td><td>No</td></tr><tr><td class='lessen'>67</td><td><a href='https://ensembl.org/Search/Results?q=CEP68'>CEP68</a></td><td>CEP68</td><td>18052</td><td>-0.035</td><td>-0.2233</td><td>No</td></tr><tr><td class='lessen'>68</td><td><a href='https://ensembl.org/Search/Results?q=POMT2'>POMT2</a></td><td>POMT2</td><td>18099</td><td>-0.036</td><td>-0.2223</td><td>No</td></tr><tr><td class='lessen'>69</td><td><a href='https://ensembl.org/Search/Results?q=DIP2C'>DIP2C</a></td><td>DIP2C</td><td>18687</td><td>-0.048</td><td>-0.2428</td><td>No</td></tr><tr><td class='lessen'>70</td><td><a href='https://ensembl.org/Search/Results?q=BAG5'>BAG5</a></td><td>BAG5</td><td>18856</td><td>-0.051</td><td>-0.2456</td><td>No</td></tr><tr><td class='lessen'>71</td><td><a href='https://ensembl.org/Search/Results?q=CDC42BPB'>CDC42BPB</a></td><td>CDC42BPB</td><td>18934</td><td>-0.054</td><td>-0.2446</td><td>No</td></tr><tr><td class='lessen'>72</td><td><a href='https://ensembl.org/Search/Results?q=ALDH6A1'>ALDH6A1</a></td><td>ALDH6A1</td><td>18972</td><td>-0.055</td><td>-0.2418</td><td>No</td></tr><tr><td class='lessen'>73</td><td><a href='https://ensembl.org/Search/Results?q=TANC2'>TANC2</a></td><td>TANC2</td><td>18997</td><td>-0.055</td><td>-0.2385</td><td>No</td></tr><tr><td class='lessen'>74</td><td><a href='https://ensembl.org/Search/Results?q=OSTF1'>OSTF1</a></td><td>OSTF1</td><td>19137</td><td>-0.059</td><td>-0.2395</td><td>No</td></tr><tr><td class='lessen'>75</td><td><a href='https://ensembl.org/Search/Results?q=ZHX2'>ZHX2</a></td><td>ZHX2</td><td>19385</td><td>-0.068</td><td>-0.2443</td><td>No</td></tr><tr><td class='lessen'>76</td><td><a href='https://ensembl.org/Search/Results?q=EFNB3'>EFNB3</a></td><td>EFNB3</td><td>19453</td><td>-0.070</td><td>-0.2416</td><td>No</td></tr><tr><td class='lessen'>77</td><td><a href='https://ensembl.org/Search/Results?q=TTYH1'>TTYH1</a></td><td>TTYH1</td><td>19522</td><td>-0.072</td><td>-0.2387</td><td>No</td></tr><tr><td class='lessen'>78</td><td><a href='https://ensembl.org/Search/Results?q=PLP2'>PLP2</a></td><td>PLP2</td><td>19799</td><td>-0.084</td><td>-0.2434</td><td>No</td></tr><tr><td class='lessen'>79</td><td><a href='https://ensembl.org/Search/Results?q=SGSM2'>SGSM2</a></td><td>SGSM2</td><td>20072</td><td>-0.097</td><td>-0.2469</td><td>No</td></tr><tr><td class='lessen'>80</td><td><a href='https://ensembl.org/Search/Results?q=LMNA'>LMNA</a></td><td>LMNA</td><td>21572</td><td>-0.210</td><td>-0.2921</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>81</td><td><a href='https://ensembl.org/Search/Results?q=KL'>KL</a></td><td>KL</td><td>22100</td><td>-0.285</td><td>-0.2913</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>82</td><td><a href='https://ensembl.org/Search/Results?q=MT3'>MT3</a></td><td>MT3</td><td>22262</td><td>-0.313</td><td>-0.2733</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>83</td><td><a href='https://ensembl.org/Search/Results?q=PROCR'>PROCR</a></td><td>PROCR</td><td>22311</td><td>-0.323</td><td>-0.2499</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>84</td><td><a href='https://ensembl.org/Search/Results?q=MICAL2'>MICAL2</a></td><td>MICAL2</td><td>23614</td><td>-0.532</td><td>-0.2615</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>85</td><td><a href='https://ensembl.org/Search/Results?q=PCP4'>PCP4</a></td><td>PCP4</td><td>23740</td><td>-0.609</td><td>-0.2187</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>86</td><td><a href='https://ensembl.org/Search/Results?q=WNT11'>WNT11</a></td><td>WNT11</td><td>23945</td><td>-0.695</td><td>-0.1725</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>87</td><td><a href='https://ensembl.org/Search/Results?q=STX3'>STX3</a></td><td>STX3</td><td>23983</td><td>-0.720</td><td>-0.1173</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>88</td><td><a href='https://ensembl.org/Search/Results?q=FXYD5'>FXYD5</a></td><td>FXYD5</td><td>24345</td><td>-1.702</td><td>0.0018</td><td bgcolor='#CCFFCC'>Yes</td></tr><caption class='table'>Table: GSEA details <a href='SALL2_REGULON.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='SALL2_REGULON' src='SALL2_REGULON_256.png'><br><br><caption>Fig 2: SALL2_REGULON    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_257.png'><br><br><caption>Fig 3: SALL2_REGULON: Random ES distribution    <br> Gene set null distribution of ES for <b>SALL2_REGULON</b></caption></div><br></body></html>