<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set WANG_CL_2017[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>NSCs_shNf1_sgFosl1.NSCs_shNf1_sgFosl1.cls<br>#Fosl1_versus_Ctrl.NSCs_shNf1_sgFosl1.cls<br>#Fosl1_versus_Ctrl_repos</td></tr><tr><td>Phenotype</td><td>NSCs_shNf1_sgFosl1.cls#Fosl1_versus_Ctrl_repos</td></tr><tr><td>Upregulated in class</td><td>Fosl1</td></tr><tr><td>GeneSet</td><td>WANG_CL_2017</td></tr><tr><td>Enrichment Score (ES)</td><td>0.3660605</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>1.3039606</td></tr><tr><td>Nominal p-value</td><td>0.12200436</td></tr><tr><td>FDR q-value</td><td>0.4720703</td></tr><tr><td>FWER p-Value</td><td>0.682</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_WANG_CL_2017' src='enplot_WANG_CL_2017_192.png'><br><br><caption>Fig 1: Enrichment plot: WANG_CL_2017    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=RASGRP1'>RASGRP1</a></td><td>RASGRP1</td><td>91</td><td>0.862</td><td>0.2171</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=GRIK1'>GRIK1</a></td><td>GRIK1</td><td>494</td><td>0.526</td><td>0.3354</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=MEOX2'>MEOX2</a></td><td>MEOX2</td><td>2727</td><td>0.218</td><td>0.2995</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=ZFHX4'>ZFHX4</a></td><td>ZFHX4</td><td>3967</td><td>0.112</td><td>0.2774</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=PAX6'>PAX6</a></td><td>PAX6</td><td>4207</td><td>0.102</td><td>0.2937</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=PLCE1'>PLCE1</a></td><td>PLCE1</td><td>4450</td><td>0.091</td><td>0.3070</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=ABLIM1'>ABLIM1</a></td><td>ABLIM1</td><td>4848</td><td>0.077</td><td>0.3103</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=ACSBG1'>ACSBG1</a></td><td>ACSBG1</td><td>5032</td><td>0.072</td><td>0.3211</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=SOX9'>SOX9</a></td><td>SOX9</td><td>5082</td><td>0.070</td><td>0.3371</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=CST3'>CST3</a></td><td>CST3</td><td>5183</td><td>0.067</td><td>0.3503</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=ELOVL2'>ELOVL2</a></td><td>ELOVL2</td><td>5216</td><td>0.067</td><td>0.3661</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=CDH4'>CDH4</a></td><td>CDH4</td><td>6583</td><td>0.041</td><td>0.3205</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=SPRY2'>SPRY2</a></td><td>SPRY2</td><td>6975</td><td>0.036</td><td>0.3136</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=MLC1'>MLC1</a></td><td>MLC1</td><td>7007</td><td>0.035</td><td>0.3214</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=PNPLA6'>PNPLA6</a></td><td>PNPLA6</td><td>7133</td><td>0.034</td><td>0.3250</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=SALL1'>SALL1</a></td><td>SALL1</td><td>8184</td><td>0.022</td><td>0.2874</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=GATM'>GATM</a></td><td>GATM</td><td>9611</td><td>0.009</td><td>0.2311</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=PHKB'>PHKB</a></td><td>PHKB</td><td>9700</td><td>0.008</td><td>0.2295</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=UPF1'>UPF1</a></td><td>UPF1</td><td>10186</td><td>0.004</td><td>0.2106</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=POLRMT'>POLRMT</a></td><td>POLRMT</td><td>10487</td><td>0.001</td><td>0.1985</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=RBCK1'>RBCK1</a></td><td>RBCK1</td><td>10614</td><td>0.000</td><td>0.1934</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=USP8'>USP8</a></td><td>USP8</td><td>14976</td><td>-0.001</td><td>0.0146</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=PLCG1'>PLCG1</a></td><td>PLCG1</td><td>14983</td><td>-0.001</td><td>0.0147</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=STXBP3'>STXBP3</a></td><td>STXBP3</td><td>15017</td><td>-0.002</td><td>0.0138</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=DENND2A'>DENND2A</a></td><td>DENND2A</td><td>15033</td><td>-0.002</td><td>0.0137</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=NPEPL1'>NPEPL1</a></td><td>NPEPL1</td><td>15487</td><td>-0.006</td><td>-0.0035</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=PPARGC1A'>PPARGC1A</a></td><td>PPARGC1A</td><td>15632</td><td>-0.007</td><td>-0.0076</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=BCKDHB'>BCKDHB</a></td><td>BCKDHB</td><td>15778</td><td>-0.008</td><td>-0.0114</td><td>No</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=TYK2'>TYK2</a></td><td>TYK2</td><td>16161</td><td>-0.012</td><td>-0.0240</td><td>No</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=SLC4A4'>SLC4A4</a></td><td>SLC4A4</td><td>16396</td><td>-0.015</td><td>-0.0299</td><td>No</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=CTNND1'>CTNND1</a></td><td>CTNND1</td><td>16459</td><td>-0.015</td><td>-0.0285</td><td>No</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=TJP1'>TJP1</a></td><td>TJP1</td><td>16525</td><td>-0.016</td><td>-0.0271</td><td>No</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=BBS1'>BBS1</a></td><td>BBS1</td><td>16872</td><td>-0.020</td><td>-0.0363</td><td>No</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=NCOA1'>NCOA1</a></td><td>NCOA1</td><td>16994</td><td>-0.021</td><td>-0.0359</td><td>No</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=SLC3A2'>SLC3A2</a></td><td>SLC3A2</td><td>17261</td><td>-0.024</td><td>-0.0406</td><td>No</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=ZHX3'>ZHX3</a></td><td>ZHX3</td><td>17664</td><td>-0.029</td><td>-0.0496</td><td>No</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=ACSL3'>ACSL3</a></td><td>ACSL3</td><td>17708</td><td>-0.030</td><td>-0.0437</td><td>No</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=PTPRA'>PTPRA</a></td><td>PTPRA</td><td>17926</td><td>-0.033</td><td>-0.0441</td><td>No</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=SEPT11'>SEPT11</a></td><td>SEPT11</td><td>18119</td><td>-0.036</td><td>-0.0426</td><td>No</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=DTNA'>DTNA</a></td><td>DTNA</td><td>19033</td><td>-0.056</td><td>-0.0658</td><td>No</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=LHFP'>LHFP</a></td><td>LHFP</td><td>19437</td><td>-0.070</td><td>-0.0645</td><td>No</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=EYA2'>EYA2</a></td><td>EYA2</td><td>19479</td><td>-0.071</td><td>-0.0479</td><td>No</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=FGFR3'>FGFR3</a></td><td>FGFR3</td><td>19566</td><td>-0.074</td><td>-0.0325</td><td>No</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=VAV3'>VAV3</a></td><td>VAV3</td><td>19782</td><td>-0.083</td><td>-0.0200</td><td>No</td></tr><tr><td class='lessen'>45</td><td><a href='https://ensembl.org/Search/Results?q=SLC20A2'>SLC20A2</a></td><td>SLC20A2</td><td>19783</td><td>-0.083</td><td>0.0013</td><td>No</td></tr><tr><td class='lessen'>46</td><td><a href='https://ensembl.org/Search/Results?q=ARNTL'>ARNTL</a></td><td>ARNTL</td><td>19932</td><td>-0.090</td><td>0.0183</td><td>No</td></tr><tr><td class='lessen'>47</td><td><a href='https://ensembl.org/Search/Results?q=MYO5C'>MYO5C</a></td><td>MYO5C</td><td>23863</td><td>-0.642</td><td>0.0216</td><td>No</td></tr><caption class='table'>Table: GSEA details <a href='WANG_CL_2017.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='WANG_CL_2017' src='WANG_CL_2017_193.png'><br><br><caption>Fig 2: WANG_CL_2017    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_194.png'><br><br><caption>Fig 3: WANG_CL_2017: Random ES distribution    <br> Gene set null distribution of ES for <b>WANG_CL_2017</b></caption></div><br></body></html>