<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set WANG_MES_2017[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>NSCs_shNf1_sgFosl1.NSCs_shNf1_sgFosl1.cls<br>#Fosl1_versus_Ctrl.NSCs_shNf1_sgFosl1.cls<br>#Fosl1_versus_Ctrl_repos</td></tr><tr><td>Phenotype</td><td>NSCs_shNf1_sgFosl1.cls#Fosl1_versus_Ctrl_repos</td></tr><tr><td>Upregulated in class</td><td>Ctrl</td></tr><tr><td>GeneSet</td><td>WANG_MES_2017</td></tr><tr><td>Enrichment Score (ES)</td><td>-0.6434542</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>-1.4328943</td></tr><tr><td>Nominal p-value</td><td>0.035164837</td></tr><tr><td>FDR q-value</td><td>0.077863455</td></tr><tr><td>FWER p-Value</td><td>0.341</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_WANG_MES_2017' src='enplot_WANG_MES_2017_243.png'><br><br><caption>Fig 1: Enrichment plot: WANG_MES_2017    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=BCL3'>BCL3</a></td><td>BCL3</td><td>167</td><td>0.756</td><td>0.0427</td><td>No</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=VDR'>VDR</a></td><td>VDR</td><td>484</td><td>0.533</td><td>0.0647</td><td>No</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=CD72'>CD72</a></td><td>CD72</td><td>681</td><td>0.442</td><td>0.0856</td><td>No</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=THBS1'>THBS1</a></td><td>THBS1</td><td>1605</td><td>0.272</td><td>0.0656</td><td>No</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=SPAG4'>SPAG4</a></td><td>SPAG4</td><td>3200</td><td>0.167</td><td>0.0110</td><td>No</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=CTSC'>CTSC</a></td><td>CTSC</td><td>3655</td><td>0.131</td><td>0.0009</td><td>No</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=ACPP'>ACPP</a></td><td>ACPP</td><td>3683</td><td>0.129</td><td>0.0083</td><td>No</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=RGS2'>RGS2</a></td><td>RGS2</td><td>4018</td><td>0.111</td><td>0.0018</td><td>No</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=TNFAIP8'>TNFAIP8</a></td><td>TNFAIP8</td><td>4331</td><td>0.096</td><td>-0.0047</td><td>No</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=PTGS2'>PTGS2</a></td><td>PTGS2</td><td>4602</td><td>0.084</td><td>-0.0102</td><td>No</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=SLPI'>SLPI</a></td><td>SLPI</td><td>5970</td><td>0.051</td><td>-0.0630</td><td>No</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=LUM'>LUM</a></td><td>LUM</td><td>6107</td><td>0.049</td><td>-0.0654</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=CDCP1'>CDCP1</a></td><td>CDCP1</td><td>6176</td><td>0.048</td><td>-0.0651</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=CYP1B1'>CYP1B1</a></td><td>CYP1B1</td><td>6429</td><td>0.043</td><td>-0.0726</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=IL6'>IL6</a></td><td>IL6</td><td>8111</td><td>0.023</td><td>-0.1402</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=SYNGR2'>SYNGR2</a></td><td>SYNGR2</td><td>15178</td><td>-0.003</td><td>-0.4303</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=ARPC1B'>ARPC1B</a></td><td>ARPC1B</td><td>15616</td><td>-0.007</td><td>-0.4478</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=ITGB1'>ITGB1</a></td><td>ITGB1</td><td>16399</td><td>-0.015</td><td>-0.4789</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=CTSB'>CTSB</a></td><td>CTSB</td><td>17332</td><td>-0.025</td><td>-0.5156</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=GLIPR1'>GLIPR1</a></td><td>GLIPR1</td><td>18201</td><td>-0.038</td><td>-0.5488</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=SDC1'>SDC1</a></td><td>SDC1</td><td>19569</td><td>-0.074</td><td>-0.6001</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=LY96'>LY96</a></td><td>LY96</td><td>19617</td><td>-0.076</td><td>-0.5970</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=RAB27A'>RAB27A</a></td><td>RAB27A</td><td>19809</td><td>-0.084</td><td>-0.5993</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=IER3'>IER3</a></td><td>IER3</td><td>20182</td><td>-0.102</td><td>-0.6079</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=IL7R'>IL7R</a></td><td>IL7R</td><td>20354</td><td>-0.109</td><td>-0.6078</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=COL1A1'>COL1A1</a></td><td>COL1A1</td><td>20681</td><td>-0.127</td><td>-0.6128</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=COL5A1'>COL5A1</a></td><td>COL5A1</td><td>20683</td><td>-0.127</td><td>-0.6045</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=RUNX1'>RUNX1</a></td><td>RUNX1</td><td>21632</td><td>-0.216</td><td>-0.6293</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=NNMT'>NNMT</a></td><td>NNMT</td><td>21893</td><td>-0.253</td><td>-0.6234</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=BACE2'>BACE2</a></td><td>BACE2</td><td>22035</td><td>-0.275</td><td>-0.6111</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=P4HA2'>P4HA2</a></td><td>P4HA2</td><td>22070</td><td>-0.281</td><td>-0.5941</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=ANPEP'>ANPEP</a></td><td>ANPEP</td><td>22140</td><td>-0.292</td><td>-0.5778</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=PRSS23'>PRSS23</a></td><td>PRSS23</td><td>22159</td><td>-0.295</td><td>-0.5593</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=RAC2'>RAC2</a></td><td>RAC2</td><td>22161</td><td>-0.295</td><td>-0.5400</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=COL1A2'>COL1A2</a></td><td>COL1A2</td><td>22387</td><td>-0.337</td><td>-0.5271</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=CNN2'>CNN2</a></td><td>CNN2</td><td>22435</td><td>-0.347</td><td>-0.5063</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=MMP7'>MMP7</a></td><td>MMP7</td><td>22835</td><td>-0.356</td><td>-0.4993</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=GPRC5A'>GPRC5A</a></td><td>GPRC5A</td><td>23055</td><td>-0.372</td><td>-0.4839</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=NDRG1'>NDRG1</a></td><td>NDRG1</td><td>23143</td><td>-0.394</td><td>-0.4617</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=PLAUR'>PLAUR</a></td><td>PLAUR</td><td>23251</td><td>-0.408</td><td>-0.4393</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=S100A11'>S100A11</a></td><td>S100A11</td><td>23510</td><td>-0.487</td><td>-0.4180</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=COL3A1'>COL3A1</a></td><td>COL3A1</td><td>24022</td><td>-0.757</td><td>-0.3894</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=TGFBI'>TGFBI</a></td><td>TGFBI</td><td>24073</td><td>-0.818</td><td>-0.3378</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=COL15A1'>COL15A1</a></td><td>COL15A1</td><td>24141</td><td>-0.936</td><td>-0.2792</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>45</td><td><a href='https://ensembl.org/Search/Results?q=CAV1'>CAV1</a></td><td>CAV1</td><td>24167</td><td>-1.007</td><td>-0.2142</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>46</td><td><a href='https://ensembl.org/Search/Results?q=BNC2'>BNC2</a></td><td>BNC2</td><td>24170</td><td>-1.012</td><td>-0.1479</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>47</td><td><a href='https://ensembl.org/Search/Results?q=LOX'>LOX</a></td><td>LOX</td><td>24181</td><td>-1.034</td><td>-0.0805</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>48</td><td><a href='https://ensembl.org/Search/Results?q=RARRES1'>RARRES1</a></td><td>RARRES1</td><td>24291</td><td>-1.357</td><td>0.0040</td><td bgcolor='#CCFFCC'>Yes</td></tr><caption class='table'>Table: GSEA details <a href='WANG_MES_2017.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='WANG_MES_2017' src='WANG_MES_2017_244.png'><br><br><caption>Fig 2: WANG_MES_2017    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_245.png'><br><br><caption>Fig 3: WANG_MES_2017: Random ES distribution    <br> Gene set null distribution of ES for <b>WANG_MES_2017</b></caption></div><br></body></html>