<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set WANG_PN_2017[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>NSCs_shNf1_sgFosl1.NSCs_shNf1_sgFosl1.cls<br>#Fosl1_versus_Ctrl.NSCs_shNf1_sgFosl1.cls<br>#Fosl1_versus_Ctrl_repos</td></tr><tr><td>Phenotype</td><td>NSCs_shNf1_sgFosl1.cls#Fosl1_versus_Ctrl_repos</td></tr><tr><td>Upregulated in class</td><td>Ctrl</td></tr><tr><td>GeneSet</td><td>WANG_PN_2017</td></tr><tr><td>Enrichment Score (ES)</td><td>-0.4467241</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>-1.1449606</td></tr><tr><td>Nominal p-value</td><td>0.2254902</td></tr><tr><td>FDR q-value</td><td>0.3662339</td></tr><tr><td>FWER p-Value</td><td>0.943</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_WANG_PN_2017' src='enplot_WANG_PN_2017_264.png'><br><br><caption>Fig 1: Enrichment plot: WANG_PN_2017    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=KCNK3'>KCNK3</a></td><td>KCNK3</td><td>637</td><td>0.458</td><td>0.0228</td><td>No</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=MYT1'>MYT1</a></td><td>MYT1</td><td>772</td><td>0.427</td><td>0.0629</td><td>No</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=IL1RAPL1'>IL1RAPL1</a></td><td>IL1RAPL1</td><td>1044</td><td>0.403</td><td>0.0949</td><td>No</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=SOX10'>SOX10</a></td><td>SOX10</td><td>1218</td><td>0.350</td><td>0.1253</td><td>No</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=RAB33A'>RAB33A</a></td><td>RAB33A</td><td>1432</td><td>0.299</td><td>0.1485</td><td>No</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=MAST1'>MAST1</a></td><td>MAST1</td><td>1615</td><td>0.269</td><td>0.1698</td><td>No</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=NHLH1'>NHLH1</a></td><td>NHLH1</td><td>3110</td><td>0.175</td><td>0.1271</td><td>No</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=PCDHA9'>PCDHA9</a></td><td>PCDHA9</td><td>3292</td><td>0.159</td><td>0.1367</td><td>No</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=MYB'>MYB</a></td><td>MYB</td><td>3304</td><td>0.159</td><td>0.1532</td><td>No</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=SLC1A1'>SLC1A1</a></td><td>SLC1A1</td><td>3310</td><td>0.158</td><td>0.1699</td><td>No</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=EPHB1'>EPHB1</a></td><td>EPHB1</td><td>3890</td><td>0.116</td><td>0.1585</td><td>No</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=PKMYT1'>PKMYT1</a></td><td>PKMYT1</td><td>4109</td><td>0.106</td><td>0.1609</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=PTTG1'>PTTG1</a></td><td>PTTG1</td><td>4337</td><td>0.096</td><td>0.1619</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=GABRB3'>GABRB3</a></td><td>GABRB3</td><td>4414</td><td>0.093</td><td>0.1687</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=CENPJ'>CENPJ</a></td><td>CENPJ</td><td>4429</td><td>0.092</td><td>0.1779</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=GRID2'>GRID2</a></td><td>GRID2</td><td>4458</td><td>0.090</td><td>0.1864</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=RASL11B'>RASL11B</a></td><td>RASL11B</td><td>4608</td><td>0.084</td><td>0.1893</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=BCL11A'>BCL11A</a></td><td>BCL11A</td><td>4808</td><td>0.078</td><td>0.1894</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=MTSS1'>MTSS1</a></td><td>MTSS1</td><td>5265</td><td>0.065</td><td>0.1777</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=HN1'>HN1</a></td><td>HN1</td><td>5391</td><td>0.062</td><td>0.1792</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=HDAC2'>HDAC2</a></td><td>HDAC2</td><td>9019</td><td>0.014</td><td>0.0317</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=PFDN2'>PFDN2</a></td><td>PFDN2</td><td>9506</td><td>0.010</td><td>0.0128</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=NPPA'>NPPA</a></td><td>NPPA</td><td>11467</td><td>0.000</td><td>-0.0677</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=HOXD3'>HOXD3</a></td><td>HOXD3</td><td>13006</td><td>0.000</td><td>-0.1309</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=KLRC3'>KLRC3</a></td><td>KLRC3</td><td>13097</td><td>0.000</td><td>-0.1346</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=TCP1'>TCP1</a></td><td>TCP1</td><td>16329</td><td>-0.014</td><td>-0.2658</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=NARF'>NARF</a></td><td>NARF</td><td>16761</td><td>-0.018</td><td>-0.2816</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=GPR17'>GPR17</a></td><td>GPR17</td><td>17695</td><td>-0.030</td><td>-0.3167</td><td>No</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=DCTN3'>DCTN3</a></td><td>DCTN3</td><td>17984</td><td>-0.034</td><td>-0.3249</td><td>No</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=PAK7'>PAK7</a></td><td>PAK7</td><td>18524</td><td>-0.044</td><td>-0.3423</td><td>No</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=PLCB4'>PLCB4</a></td><td>PLCB4</td><td>18763</td><td>-0.049</td><td>-0.3468</td><td>No</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=SMPD3'>SMPD3</a></td><td>SMPD3</td><td>18792</td><td>-0.050</td><td>-0.3426</td><td>No</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=BAMBI'>BAMBI</a></td><td>BAMBI</td><td>19650</td><td>-0.077</td><td>-0.3695</td><td>No</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=PDGFRA'>PDGFRA</a></td><td>PDGFRA</td><td>20280</td><td>-0.106</td><td>-0.3840</td><td>No</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=SLC17A6'>SLC17A6</a></td><td>SLC17A6</td><td>20679</td><td>-0.127</td><td>-0.3868</td><td>No</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=DACH1'>DACH1</a></td><td>DACH1</td><td>22139</td><td>-0.291</td><td>-0.4156</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=VIPR2'>VIPR2</a></td><td>VIPR2</td><td>22235</td><td>-0.309</td><td>-0.3864</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=JPH3'>JPH3</a></td><td>JPH3</td><td>22446</td><td>-0.349</td><td>-0.3577</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=ERBB3'>ERBB3</a></td><td>ERBB3</td><td>22455</td><td>-0.351</td><td>-0.3205</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=SIM2'>SIM2</a></td><td>SIM2</td><td>22984</td><td>-0.360</td><td>-0.3037</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=KLRK1'>KLRK1</a></td><td>KLRK1</td><td>22992</td><td>-0.361</td><td>-0.2654</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=CDKN1C'>CDKN1C</a></td><td>CDKN1C</td><td>23319</td><td>-0.424</td><td>-0.2335</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=NMU'>NMU</a></td><td>NMU</td><td>24013</td><td>-0.750</td><td>-0.1817</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=CLGN'>CLGN</a></td><td>CLGN</td><td>24125</td><td>-0.920</td><td>-0.0879</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>45</td><td><a href='https://ensembl.org/Search/Results?q=HRASLS'>HRASLS</a></td><td>HRASLS</td><td>24130</td><td>-0.922</td><td>0.0106</td><td bgcolor='#CCFFCC'>Yes</td></tr><caption class='table'>Table: GSEA details <a href='WANG_PN_2017.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='WANG_PN_2017' src='WANG_PN_2017_265.png'><br><br><caption>Fig 2: WANG_PN_2017    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_266.png'><br><br><caption>Fig 3: WANG_PN_2017: Random ES distribution    <br> Gene set null distribution of ES for <b>WANG_PN_2017</b></caption></div><br></body></html>