<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set NEFTEL_G1.S_2019[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>ranaseq_carol_ns_sel_exprs.ranaseq_carol_ns_sel_phenotype.cls<br>#Fosl1_1_versus_Ctrl</td></tr><tr><td>Phenotype</td><td>ranaseq_carol_ns_sel_phenotype.cls#Fosl1_1_versus_Ctrl</td></tr><tr><td>Upregulated in class</td><td>Ctrl</td></tr><tr><td>GeneSet</td><td>NEFTEL_G1.S_2019</td></tr><tr><td>Enrichment Score (ES)</td><td>-0.7662635</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>-1.8163855</td></tr><tr><td>Nominal p-value</td><td>0.0</td></tr><tr><td>FDR q-value</td><td>9.2105256E-5</td></tr><tr><td>FWER p-Value</td><td>0.001</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_NEFTEL_G1.S_2019' src='enplot_NEFTEL_G1.S_2019_360.png'><br><br><caption>Fig 1: Enrichment plot: NEFTEL_G1.S_2019    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=MCM7'>MCM7</a></td><td>MCM7</td><td>7093</td><td>0.181</td><td>-0.3115</td><td>No</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=ZWINT'>ZWINT</a></td><td>ZWINT</td><td>7468</td><td>0.150</td><td>-0.3212</td><td>No</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=TMEM106C'>TMEM106C</a></td><td>TMEM106C</td><td>8340</td><td>0.096</td><td>-0.3559</td><td>No</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=RRM1'>RRM1</a></td><td>RRM1</td><td>9947</td><td>0.001</td><td>-0.4284</td><td>No</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=HIST1H4C'>HIST1H4C</a></td><td>HIST1H4C</td><td>10296</td><td>0.000</td><td>-0.4441</td><td>No</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=GMNN'>GMNN</a></td><td>GMNN</td><td>13435</td><td>-0.020</td><td>-0.5848</td><td>No</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=RNASEH2A'>RNASEH2A</a></td><td>RNASEH2A</td><td>15203</td><td>-0.149</td><td>-0.6574</td><td>No</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=FEN1'>FEN1</a></td><td>FEN1</td><td>15472</td><td>-0.176</td><td>-0.6611</td><td>No</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=MCM4'>MCM4</a></td><td>MCM4</td><td>16358</td><td>-0.276</td><td>-0.6878</td><td>No</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=CKS1B'>CKS1B</a></td><td>CKS1B</td><td>16823</td><td>-0.352</td><td>-0.6918</td><td>No</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=GINS2'>GINS2</a></td><td>GINS2</td><td>16979</td><td>-0.377</td><td>-0.6807</td><td>No</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=DUT'>DUT</a></td><td>DUT</td><td>17056</td><td>-0.392</td><td>-0.6653</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=PCNA'>PCNA</a></td><td>PCNA</td><td>17597</td><td>-0.514</td><td>-0.6649</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=MCM3'>MCM3</a></td><td>MCM3</td><td>19843</td><td>-0.735</td><td>-0.7309</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=MCM2'>MCM2</a></td><td>MCM2</td><td>19937</td><td>-0.790</td><td>-0.6972</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=CENPK'>CENPK</a></td><td>CENPK</td><td>20267</td><td>-0.991</td><td>-0.6644</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=PKMYT1'>PKMYT1</a></td><td>PKMYT1</td><td>20357</td><td>-1.050</td><td>-0.6179</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=RRM2'>RRM2</a></td><td>RRM2</td><td>20373</td><td>-1.063</td><td>-0.5675</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=CDCA5'>CDCA5</a></td><td>CDCA5</td><td>20482</td><td>-1.137</td><td>-0.5177</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=CDC45'>CDC45</a></td><td>CDC45</td><td>20737</td><td>-1.338</td><td>-0.4648</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=MELK'>MELK</a></td><td>MELK</td><td>20777</td><td>-1.368</td><td>-0.4008</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=RAD51AP1'>RAD51AP1</a></td><td>RAD51AP1</td><td>20805</td><td>-1.393</td><td>-0.3351</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=TK1'>TK1</a></td><td>TK1</td><td>20812</td><td>-1.404</td><td>-0.2679</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=CCNE2'>CCNE2</a></td><td>CCNE2</td><td>20883</td><td>-1.464</td><td>-0.2007</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=ASF1B'>ASF1B</a></td><td>ASF1B</td><td>21020</td><td>-1.641</td><td>-0.1280</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=CENPM'>CENPM</a></td><td>CENPM</td><td>21121</td><td>-1.763</td><td>-0.0477</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=AURKB'>AURKB</a></td><td>AURKB</td><td>21275</td><td>-1.983</td><td>0.0407</td><td bgcolor='#CCFFCC'>Yes</td></tr><caption class='table'>Table: GSEA details <a href='NEFTEL_G1.S_2019.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='NEFTEL_G1.S_2019' src='NEFTEL_G1.S_2019_361.png'><br><br><caption>Fig 2: NEFTEL_G1.S_2019    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_362.png'><br><br><caption>Fig 3: NEFTEL_G1.S_2019: Random ES distribution    <br> Gene set null distribution of ES for <b>NEFTEL_G1.S_2019</b></caption></div><br></body></html>