<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set NEFTEL_G2.M_2019[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>ranaseq_carol_ns_sel_exprs.ranaseq_carol_ns_sel_phenotype.cls<br>#Fosl1_1_versus_Ctrl</td></tr><tr><td>Phenotype</td><td>ranaseq_carol_ns_sel_phenotype.cls#Fosl1_1_versus_Ctrl</td></tr><tr><td>Upregulated in class</td><td>Ctrl</td></tr><tr><td>GeneSet</td><td>NEFTEL_G2.M_2019</td></tr><tr><td>Enrichment Score (ES)</td><td>-0.6988124</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>-1.8330988</td></tr><tr><td>Nominal p-value</td><td>0.0</td></tr><tr><td>FDR q-value</td><td>1.00478464E-4</td></tr><tr><td>FWER p-Value</td><td>0.001</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_NEFTEL_G2.M_2019' src='enplot_NEFTEL_G2.M_2019_357.png'><br><br><caption>Fig 1: Enrichment plot: NEFTEL_G2.M_2019    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=HMGB3'>HMGB3</a></td><td>HMGB3</td><td>1517</td><td>1.098</td><td>-0.0357</td><td>No</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=MZT1'>MZT1</a></td><td>MZT1</td><td>4247</td><td>0.582</td><td>-0.1416</td><td>No</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=NCAPD2'>NCAPD2</a></td><td>NCAPD2</td><td>8680</td><td>0.075</td><td>-0.3396</td><td>No</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=GPSM2'>GPSM2</a></td><td>GPSM2</td><td>8746</td><td>0.071</td><td>-0.3405</td><td>No</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=KPNA2'>KPNA2</a></td><td>KPNA2</td><td>13030</td><td>-0.001</td><td>-0.5340</td><td>No</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=ARL6IP1'>ARL6IP1</a></td><td>ARL6IP1</td><td>13945</td><td>-0.055</td><td>-0.5736</td><td>No</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=TMPO'>TMPO</a></td><td>TMPO</td><td>13973</td><td>-0.058</td><td>-0.5731</td><td>No</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=RANGAP1'>RANGAP1</a></td><td>RANGAP1</td><td>14341</td><td>-0.084</td><td>-0.5872</td><td>No</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=H2AFZ'>H2AFZ</a></td><td>H2AFZ</td><td>14721</td><td>-0.114</td><td>-0.6009</td><td>No</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=CKAP2'>CKAP2</a></td><td>CKAP2</td><td>15489</td><td>-0.178</td><td>-0.6302</td><td>No</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=ANP32E'>ANP32E</a></td><td>ANP32E</td><td>15494</td><td>-0.178</td><td>-0.6251</td><td>No</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=CDC25B'>CDC25B</a></td><td>CDC25B</td><td>15666</td><td>-0.196</td><td>-0.6270</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=SPAG5'>SPAG5</a></td><td>SPAG5</td><td>16162</td><td>-0.251</td><td>-0.6418</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=TUBA1C'>TUBA1C</a></td><td>TUBA1C</td><td>16681</td><td>-0.326</td><td>-0.6555</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=TUBB4B'>TUBB4B</a></td><td>TUBB4B</td><td>16738</td><td>-0.336</td><td>-0.6480</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=SMC4'>SMC4</a></td><td>SMC4</td><td>16828</td><td>-0.353</td><td>-0.6415</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=TACC3'>TACC3</a></td><td>TACC3</td><td>16942</td><td>-0.371</td><td>-0.6355</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=ARHGAP11A'>ARHGAP11A</a></td><td>ARHGAP11A</td><td>17763</td><td>-0.572</td><td>-0.6554</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=REEP4'>REEP4</a></td><td>REEP4</td><td>17804</td><td>-0.585</td><td>-0.6398</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=OIP5'>OIP5</a></td><td>OIP5</td><td>18959</td><td>-0.605</td><td>-0.6738</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=PLK1'>PLK1</a></td><td>PLK1</td><td>19513</td><td>-0.657</td><td>-0.6792</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=KIF11'>KIF11</a></td><td>KIF11</td><td>19576</td><td>-0.678</td><td>-0.6617</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=KNSTRN'>KNSTRN</a></td><td>KNSTRN</td><td>19852</td><td>-0.739</td><td>-0.6521</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=CCNB2'>CCNB2</a></td><td>CCNB2</td><td>19981</td><td>-0.813</td><td>-0.6336</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=CENPF'>CENPF</a></td><td>CENPF</td><td>20028</td><td>-0.842</td><td>-0.6105</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=KIF20A'>KIF20A</a></td><td>KIF20A</td><td>20033</td><td>-0.845</td><td>-0.5855</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=CCNA2'>CCNA2</a></td><td>CCNA2</td><td>20064</td><td>-0.865</td><td>-0.5610</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=CDCA8'>CDCA8</a></td><td>CDCA8</td><td>20084</td><td>-0.880</td><td>-0.5356</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=RACGAP1'>RACGAP1</a></td><td>RACGAP1</td><td>20113</td><td>-0.897</td><td>-0.5100</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=CCNB1'>CCNB1</a></td><td>CCNB1</td><td>20155</td><td>-0.923</td><td>-0.4843</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=FOXM1'>FOXM1</a></td><td>FOXM1</td><td>20182</td><td>-0.938</td><td>-0.4575</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=AURKA'>AURKA</a></td><td>AURKA</td><td>20225</td><td>-0.963</td><td>-0.4306</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=CDCA3'>CDCA3</a></td><td>CDCA3</td><td>20253</td><td>-0.983</td><td>-0.4025</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=TROAP'>TROAP</a></td><td>TROAP</td><td>20263</td><td>-0.988</td><td>-0.3734</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=CKAP2L'>CKAP2L</a></td><td>CKAP2L</td><td>20282</td><td>-0.997</td><td>-0.3444</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=BUB1B'>BUB1B</a></td><td>BUB1B</td><td>20291</td><td>-1.005</td><td>-0.3147</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=PSRC1'>PSRC1</a></td><td>PSRC1</td><td>20510</td><td>-1.152</td><td>-0.2902</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=ECT2'>ECT2</a></td><td>ECT2</td><td>20543</td><td>-1.176</td><td>-0.2565</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=CDC20'>CDC20</a></td><td>CDC20</td><td>20647</td><td>-1.257</td><td>-0.2236</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=KIFC1'>KIFC1</a></td><td>KIFC1</td><td>20728</td><td>-1.331</td><td>-0.1874</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=BUB1'>BUB1</a></td><td>BUB1</td><td>20907</td><td>-1.487</td><td>-0.1511</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=KIF2C'>KIF2C</a></td><td>KIF2C</td><td>21278</td><td>-1.987</td><td>-0.1084</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=TTK'>TTK</a></td><td>TTK</td><td>21280</td><td>-1.994</td><td>-0.0489</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=MXD3'>MXD3</a></td><td>MXD3</td><td>21733</td><td>-2.991</td><td>0.0200</td><td bgcolor='#CCFFCC'>Yes</td></tr><caption class='table'>Table: GSEA details <a href='NEFTEL_G2.M_2019.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='NEFTEL_G2.M_2019' src='NEFTEL_G2.M_2019_358.png'><br><br><caption>Fig 2: NEFTEL_G2.M_2019    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_359.png'><br><br><caption>Fig 3: NEFTEL_G2.M_2019: Random ES distribution    <br> Gene set null distribution of ES for <b>NEFTEL_G2.M_2019</b></caption></div><br></body></html>