<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set NEFTEL_MES1_2019[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>ranaseq_carol_ns_sel_exprs.ranaseq_carol_ns_sel_phenotype.cls<br>#Fosl1_1_versus_Ctrl</td></tr><tr><td>Phenotype</td><td>ranaseq_carol_ns_sel_phenotype.cls#Fosl1_1_versus_Ctrl</td></tr><tr><td>Upregulated in class</td><td>Ctrl</td></tr><tr><td>GeneSet</td><td>NEFTEL_MES1_2019</td></tr><tr><td>Enrichment Score (ES)</td><td>-0.6308056</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>-1.6670926</td></tr><tr><td>Nominal p-value</td><td>0.0018018018</td></tr><tr><td>FDR q-value</td><td>0.001781849</td></tr><tr><td>FWER p-Value</td><td>0.024</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_NEFTEL_MES1_2019' src='enplot_NEFTEL_MES1_2019_369.png'><br><br><caption>Fig 1: Enrichment plot: NEFTEL_MES1_2019    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=SERPING1'>SERPING1</a></td><td>SERPING1</td><td>28</td><td>5.000</td><td>0.0969</td><td>No</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=GFPT2'>GFPT2</a></td><td>GFPT2</td><td>1032</td><td>1.434</td><td>0.0798</td><td>No</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=S100A16'>S100A16</a></td><td>S100A16</td><td>1093</td><td>1.381</td><td>0.1042</td><td>No</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=APOE'>APOE</a></td><td>APOE</td><td>2626</td><td>0.685</td><td>0.0484</td><td>No</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=PRDX6'>PRDX6</a></td><td>PRDX6</td><td>5142</td><td>0.400</td><td>-0.0573</td><td>No</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=LGALS3'>LGALS3</a></td><td>LGALS3</td><td>5240</td><td>0.386</td><td>-0.0542</td><td>No</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=MGST1'>MGST1</a></td><td>MGST1</td><td>6614</td><td>0.224</td><td>-0.1118</td><td>No</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=RCAN1'>RCAN1</a></td><td>RCAN1</td><td>6791</td><td>0.207</td><td>-0.1157</td><td>No</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=SOD2'>SOD2</a></td><td>SOD2</td><td>7853</td><td>0.129</td><td>-0.1611</td><td>No</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=NPC2'>NPC2</a></td><td>NPC2</td><td>8485</td><td>0.088</td><td>-0.1878</td><td>No</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=C3'>C3</a></td><td>C3</td><td>8663</td><td>0.075</td><td>-0.1944</td><td>No</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=CTSB'>CTSB</a></td><td>CTSB</td><td>14332</td><td>-0.083</td><td>-0.4488</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=CLIC4'>CLIC4</a></td><td>CLIC4</td><td>14489</td><td>-0.094</td><td>-0.4540</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=GJA1'>GJA1</a></td><td>GJA1</td><td>15671</td><td>-0.196</td><td>-0.5035</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=TUBA1C'>TUBA1C</a></td><td>TUBA1C</td><td>16681</td><td>-0.326</td><td>-0.5427</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=WWTR1'>WWTR1</a></td><td>WWTR1</td><td>17052</td><td>-0.391</td><td>-0.5517</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=VIM'>VIM</a></td><td>VIM</td><td>17087</td><td>-0.398</td><td>-0.5454</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=S100A10'>S100A10</a></td><td>S100A10</td><td>17113</td><td>-0.401</td><td>-0.5387</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=GSN'>GSN</a></td><td>GSN</td><td>17154</td><td>-0.410</td><td>-0.5324</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=TNFRSF1A'>TNFRSF1A</a></td><td>TNFRSF1A</td><td>17424</td><td>-0.466</td><td>-0.5354</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=NAMPT'>NAMPT</a></td><td>NAMPT</td><td>17463</td><td>-0.475</td><td>-0.5278</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=IGFBP7'>IGFBP7</a></td><td>IGFBP7</td><td>19728</td><td>-0.709</td><td>-0.6162</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=A2M'>A2M</a></td><td>A2M</td><td>20053</td><td>-0.858</td><td>-0.6140</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=CLIC1'>CLIC1</a></td><td>CLIC1</td><td>20133</td><td>-0.913</td><td>-0.5996</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=ACTN1'>ACTN1</a></td><td>ACTN1</td><td>20344</td><td>-1.040</td><td>-0.5887</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=LGALS1'>LGALS1</a></td><td>LGALS1</td><td>20466</td><td>-1.122</td><td>-0.5721</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=CD44'>CD44</a></td><td>CD44</td><td>20484</td><td>-1.138</td><td>-0.5505</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=IFITM3'>IFITM3</a></td><td>IFITM3</td><td>20666</td><td>-1.284</td><td>-0.5335</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=EMP1'>EMP1</a></td><td>EMP1</td><td>20675</td><td>-1.290</td><td>-0.5085</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=TAGLN2'>TAGLN2</a></td><td>TAGLN2</td><td>20860</td><td>-1.446</td><td>-0.4884</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=TIMP1'>TIMP1</a></td><td>TIMP1</td><td>21019</td><td>-1.640</td><td>-0.4633</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=ANXA2'>ANXA2</a></td><td>ANXA2</td><td>21058</td><td>-1.695</td><td>-0.4318</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=MGP'>MGP</a></td><td>MGP</td><td>21155</td><td>-1.824</td><td>-0.4003</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=FN1'>FN1</a></td><td>FN1</td><td>21172</td><td>-1.840</td><td>-0.3649</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=SERPINE1'>SERPINE1</a></td><td>SERPINE1</td><td>21444</td><td>-2.262</td><td>-0.3327</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=SPP1'>SPP1</a></td><td>SPP1</td><td>21467</td><td>-2.320</td><td>-0.2882</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=EMP3'>EMP3</a></td><td>EMP3</td><td>21469</td><td>-2.325</td><td>-0.2426</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=ANXA1'>ANXA1</a></td><td>ANXA1</td><td>21470</td><td>-2.327</td><td>-0.1969</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=NNMT'>NNMT</a></td><td>NNMT</td><td>21524</td><td>-2.484</td><td>-0.1505</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=S100A11'>S100A11</a></td><td>S100A11</td><td>21526</td><td>-2.486</td><td>-0.1017</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=EFEMP1'>EFEMP1</a></td><td>EFEMP1</td><td>21673</td><td>-2.868</td><td>-0.0520</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=PLP2'>PLP2</a></td><td>PLP2</td><td>21823</td><td>-3.803</td><td>0.0159</td><td bgcolor='#CCFFCC'>Yes</td></tr><caption class='table'>Table: GSEA details <a href='NEFTEL_MES1_2019.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='NEFTEL_MES1_2019' src='NEFTEL_MES1_2019_370.png'><br><br><caption>Fig 2: NEFTEL_MES1_2019    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_371.png'><br><br><caption>Fig 3: NEFTEL_MES1_2019: Random ES distribution    <br> Gene set null distribution of ES for <b>NEFTEL_MES1_2019</b></caption></div><br></body></html>