<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set NEFTEL_MES2_2019[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>ranaseq_carol_ns_sel_exprs.ranaseq_carol_ns_sel_phenotype.cls<br>#Fosl1_1_versus_Ctrl</td></tr><tr><td>Phenotype</td><td>ranaseq_carol_ns_sel_phenotype.cls#Fosl1_1_versus_Ctrl</td></tr><tr><td>Upregulated in class</td><td>Ctrl</td></tr><tr><td>GeneSet</td><td>NEFTEL_MES2_2019</td></tr><tr><td>Enrichment Score (ES)</td><td>-0.6336744</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>-1.6920484</td></tr><tr><td>Nominal p-value</td><td>0.0017123288</td></tr><tr><td>FDR q-value</td><td>0.0012835418</td></tr><tr><td>FWER p-Value</td><td>0.017</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_NEFTEL_MES2_2019' src='enplot_NEFTEL_MES2_2019_366.png'><br><br><caption>Fig 1: Enrichment plot: NEFTEL_MES2_2019    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=ANGPTL4'>ANGPTL4</a></td><td>ANGPTL4</td><td>550</td><td>2.260</td><td>0.0320</td><td>No</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=EPAS1'>EPAS1</a></td><td>EPAS1</td><td>3203</td><td>0.630</td><td>-0.0720</td><td>No</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=LGALS3'>LGALS3</a></td><td>LGALS3</td><td>5240</td><td>0.386</td><td>-0.1543</td><td>No</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=BNIP3L'>BNIP3L</a></td><td>BNIP3L</td><td>5981</td><td>0.288</td><td>-0.1805</td><td>No</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=UFM1'>UFM1</a></td><td>UFM1</td><td>8034</td><td>0.117</td><td>-0.2703</td><td>No</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=RPL21'>RPL21</a></td><td>RPL21</td><td>8073</td><td>0.114</td><td>-0.2691</td><td>No</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=HILPDA'>HILPDA</a></td><td>HILPDA</td><td>13192</td><td>-0.003</td><td>-0.5003</td><td>No</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=AKAP12'>AKAP12</a></td><td>AKAP12</td><td>13357</td><td>-0.014</td><td>-0.5074</td><td>No</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=GBE1'>GBE1</a></td><td>GBE1</td><td>14025</td><td>-0.062</td><td>-0.5360</td><td>No</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=DNAJB9'>DNAJB9</a></td><td>DNAJB9</td><td>14720</td><td>-0.113</td><td>-0.5645</td><td>No</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=BNIP3'>BNIP3</a></td><td>BNIP3</td><td>15769</td><td>-0.208</td><td>-0.6066</td><td>No</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=INSIG2'>INSIG2</a></td><td>INSIG2</td><td>16066</td><td>-0.240</td><td>-0.6140</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=SLC39A14'>SLC39A14</a></td><td>SLC39A14</td><td>16396</td><td>-0.281</td><td>-0.6217</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=TRAM1'>TRAM1</a></td><td>TRAM1</td><td>16463</td><td>-0.291</td><td>-0.6174</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=WARS'>WARS</a></td><td>WARS</td><td>16824</td><td>-0.352</td><td>-0.6248</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=HSPA9'>HSPA9</a></td><td>HSPA9</td><td>16899</td><td>-0.363</td><td>-0.6190</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=HSPA5'>HSPA5</a></td><td>HSPA5</td><td>16923</td><td>-0.367</td><td>-0.6108</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=XPOT'>XPOT</a></td><td>XPOT</td><td>16956</td><td>-0.373</td><td>-0.6029</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=VIM'>VIM</a></td><td>VIM</td><td>17087</td><td>-0.398</td><td>-0.5988</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=SQSTM1'>SQSTM1</a></td><td>SQSTM1</td><td>17102</td><td>-0.401</td><td>-0.5893</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=P4HA1'>P4HA1</a></td><td>P4HA1</td><td>17236</td><td>-0.425</td><td>-0.5846</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=GOLT1B'>GOLT1B</a></td><td>GOLT1B</td><td>17401</td><td>-0.462</td><td>-0.5804</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=NAMPT'>NAMPT</a></td><td>NAMPT</td><td>17463</td><td>-0.475</td><td>-0.5713</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=HERPUD1'>HERPUD1</a></td><td>HERPUD1</td><td>17501</td><td>-0.487</td><td>-0.5607</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=EGLN3'>EGLN3</a></td><td>EGLN3</td><td>17552</td><td>-0.503</td><td>-0.5503</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=LDHA'>LDHA</a></td><td>LDHA</td><td>17712</td><td>-0.550</td><td>-0.5437</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=SLC2A3'>SLC2A3</a></td><td>SLC2A3</td><td>17819</td><td>-0.591</td><td>-0.5336</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=PGK1'>PGK1</a></td><td>PGK1</td><td>18990</td><td>-0.614</td><td>-0.5710</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=DDIT3'>DDIT3</a></td><td>DDIT3</td><td>19757</td><td>-0.711</td><td>-0.5878</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=SLC6A6'>SLC6A6</a></td><td>SLC6A6</td><td>19833</td><td>-0.731</td><td>-0.5728</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=ENO2'>ENO2</a></td><td>ENO2</td><td>20010</td><td>-0.831</td><td>-0.5599</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=PPP1R15A'>PPP1R15A</a></td><td>PPP1R15A</td><td>20124</td><td>-0.908</td><td>-0.5421</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=ADM'>ADM</a></td><td>ADM</td><td>20213</td><td>-0.959</td><td>-0.5220</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=PLOD2'>PLOD2</a></td><td>PLOD2</td><td>20229</td><td>-0.966</td><td>-0.4984</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=CDKN1A'>CDKN1A</a></td><td>CDKN1A</td><td>20334</td><td>-1.035</td><td>-0.4771</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=ASNS'>ASNS</a></td><td>ASNS</td><td>20396</td><td>-1.082</td><td>-0.4527</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=ERO1L'>ERO1L</a></td><td>ERO1L</td><td>20474</td><td>-1.128</td><td>-0.4278</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=SERTAD1'>SERTAD1</a></td><td>SERTAD1</td><td>20654</td><td>-1.268</td><td>-0.4040</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=PFKP'>PFKP</a></td><td>PFKP</td><td>20914</td><td>-1.497</td><td>-0.3781</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=IGFBP3'>IGFBP3</a></td><td>IGFBP3</td><td>20978</td><td>-1.584</td><td>-0.3411</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=NDRG1'>NDRG1</a></td><td>NDRG1</td><td>21010</td><td>-1.628</td><td>-0.3015</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=ANXA2'>ANXA2</a></td><td>ANXA2</td><td>21058</td><td>-1.695</td><td>-0.2611</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=TRIB3'>TRIB3</a></td><td>TRIB3</td><td>21220</td><td>-1.897</td><td>-0.2207</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=SLC2A1'>SLC2A1</a></td><td>SLC2A1</td><td>21341</td><td>-2.076</td><td>-0.1739</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>45</td><td><a href='https://ensembl.org/Search/Results?q=NRN1'>NRN1</a></td><td>NRN1</td><td>21370</td><td>-2.141</td><td>-0.1213</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>46</td><td><a href='https://ensembl.org/Search/Results?q=GDF15'>GDF15</a></td><td>GDF15</td><td>21468</td><td>-2.323</td><td>-0.0673</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>47</td><td><a href='https://ensembl.org/Search/Results?q=ATF3'>ATF3</a></td><td>ATF3</td><td>21828</td><td>-3.948</td><td>0.0157</td><td bgcolor='#CCFFCC'>Yes</td></tr><caption class='table'>Table: GSEA details <a href='NEFTEL_MES2_2019.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='NEFTEL_MES2_2019' src='NEFTEL_MES2_2019_367.png'><br><br><caption>Fig 2: NEFTEL_MES2_2019    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_368.png'><br><br><caption>Fig 3: NEFTEL_MES2_2019: Random ES distribution    <br> Gene set null distribution of ES for <b>NEFTEL_MES2_2019</b></caption></div><br></body></html>