<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set POU3F3_REGULON[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>ranaseq_carol_ns_sel_exprs.ranaseq_carol_ns_sel_phenotype.cls<br>#Fosl1_1_versus_Ctrl</td></tr><tr><td>Phenotype</td><td>ranaseq_carol_ns_sel_phenotype.cls#Fosl1_1_versus_Ctrl</td></tr><tr><td>Upregulated in class</td><td>Ctrl</td></tr><tr><td>GeneSet</td><td>POU3F3_REGULON</td></tr><tr><td>Enrichment Score (ES)</td><td>-0.2952405</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>-0.876573</td></tr><tr><td>Nominal p-value</td><td>0.68793106</td></tr><tr><td>FDR q-value</td><td>0.82851064</td></tr><tr><td>FWER p-Value</td><td>1.0</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_POU3F3_REGULON' src='enplot_POU3F3_REGULON_381.png'><br><br><caption>Fig 1: Enrichment plot: POU3F3_REGULON    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=RFX4'>RFX4</a></td><td>RFX4</td><td>699</td><td>1.913</td><td>0.0012</td><td>No</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=STMN3'>STMN3</a></td><td>STMN3</td><td>1237</td><td>1.256</td><td>-0.0016</td><td>No</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=TTYH1'>TTYH1</a></td><td>TTYH1</td><td>1289</td><td>1.228</td><td>0.0172</td><td>No</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=NCALD'>NCALD</a></td><td>NCALD</td><td>1316</td><td>1.210</td><td>0.0368</td><td>No</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=FAM131B'>FAM131B</a></td><td>FAM131B</td><td>1325</td><td>1.204</td><td>0.0571</td><td>No</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=PDE4B'>PDE4B</a></td><td>PDE4B</td><td>1434</td><td>1.142</td><td>0.0718</td><td>No</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=ADD2'>ADD2</a></td><td>ADD2</td><td>1516</td><td>1.099</td><td>0.0870</td><td>No</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=KCNA2'>KCNA2</a></td><td>KCNA2</td><td>1546</td><td>1.087</td><td>0.1044</td><td>No</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=MEIS2'>MEIS2</a></td><td>MEIS2</td><td>1638</td><td>1.038</td><td>0.1181</td><td>No</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=CDH4'>CDH4</a></td><td>CDH4</td><td>1768</td><td>0.972</td><td>0.1289</td><td>No</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=EFR3B'>EFR3B</a></td><td>EFR3B</td><td>1824</td><td>0.947</td><td>0.1427</td><td>No</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=PIK3C2B'>PIK3C2B</a></td><td>PIK3C2B</td><td>1839</td><td>0.940</td><td>0.1582</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=CACNG4'>CACNG4</a></td><td>CACNG4</td><td>1847</td><td>0.934</td><td>0.1739</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=FABP7'>FABP7</a></td><td>FABP7</td><td>1891</td><td>0.914</td><td>0.1876</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=SV2A'>SV2A</a></td><td>SV2A</td><td>2099</td><td>0.820</td><td>0.1923</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=PCDH9'>PCDH9</a></td><td>PCDH9</td><td>2222</td><td>0.768</td><td>0.2000</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=FZD3'>FZD3</a></td><td>FZD3</td><td>2478</td><td>0.715</td><td>0.2007</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=PURG'>PURG</a></td><td>PURG</td><td>2533</td><td>0.704</td><td>0.2104</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=ABCD2'>ABCD2</a></td><td>ABCD2</td><td>2655</td><td>0.676</td><td>0.2165</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=RFX2'>RFX2</a></td><td>RFX2</td><td>2718</td><td>0.667</td><td>0.2251</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=GLUL'>GLUL</a></td><td>GLUL</td><td>2904</td><td>0.639</td><td>0.2277</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=DNMT3A'>DNMT3A</a></td><td>DNMT3A</td><td>3239</td><td>0.618</td><td>0.2232</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=TUBA1A'>TUBA1A</a></td><td>TUBA1A</td><td>4210</td><td>0.592</td><td>0.1895</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=KLHL25'>KLHL25</a></td><td>KLHL25</td><td>4243</td><td>0.584</td><td>0.1980</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=CRTC1'>CRTC1</a></td><td>CRTC1</td><td>4400</td><td>0.538</td><td>0.2002</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=LPIN1'>LPIN1</a></td><td>LPIN1</td><td>4807</td><td>0.454</td><td>0.1896</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=RGS12'>RGS12</a></td><td>RGS12</td><td>4841</td><td>0.447</td><td>0.1958</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=KIF1B'>KIF1B</a></td><td>KIF1B</td><td>5101</td><td>0.405</td><td>0.1910</td><td>No</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=SALL1'>SALL1</a></td><td>SALL1</td><td>5296</td><td>0.378</td><td>0.1887</td><td>No</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=TLE1'>TLE1</a></td><td>TLE1</td><td>5468</td><td>0.355</td><td>0.1871</td><td>No</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=UTY'>UTY</a></td><td>UTY</td><td>5933</td><td>0.295</td><td>0.1711</td><td>No</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=TEKT2'>TEKT2</a></td><td>TEKT2</td><td>6062</td><td>0.279</td><td>0.1701</td><td>No</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=SSBP2'>SSBP2</a></td><td>SSBP2</td><td>6275</td><td>0.257</td><td>0.1649</td><td>No</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=TNIP1'>TNIP1</a></td><td>TNIP1</td><td>6535</td><td>0.232</td><td>0.1572</td><td>No</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=ATF7IP'>ATF7IP</a></td><td>ATF7IP</td><td>6936</td><td>0.195</td><td>0.1424</td><td>No</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=TRIM37'>TRIM37</a></td><td>TRIM37</td><td>7008</td><td>0.190</td><td>0.1425</td><td>No</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=SCP2'>SCP2</a></td><td>SCP2</td><td>7150</td><td>0.177</td><td>0.1391</td><td>No</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=SRPK2'>SRPK2</a></td><td>SRPK2</td><td>7425</td><td>0.154</td><td>0.1294</td><td>No</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=PBX1'>PBX1</a></td><td>PBX1</td><td>7433</td><td>0.153</td><td>0.1317</td><td>No</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=DZIP3'>DZIP3</a></td><td>DZIP3</td><td>7907</td><td>0.125</td><td>0.1124</td><td>No</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=ARL3'>ARL3</a></td><td>ARL3</td><td>7967</td><td>0.122</td><td>0.1118</td><td>No</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=DUSP11'>DUSP11</a></td><td>DUSP11</td><td>8179</td><td>0.106</td><td>0.1041</td><td>No</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=ZKSCAN3'>ZKSCAN3</a></td><td>ZKSCAN3</td><td>8840</td><td>0.064</td><td>0.0753</td><td>No</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=HP1BP3'>HP1BP3</a></td><td>HP1BP3</td><td>8842</td><td>0.064</td><td>0.0764</td><td>No</td></tr><tr><td class='lessen'>45</td><td><a href='https://ensembl.org/Search/Results?q=EXTL3'>EXTL3</a></td><td>EXTL3</td><td>8890</td><td>0.060</td><td>0.0753</td><td>No</td></tr><tr><td class='lessen'>46</td><td><a href='https://ensembl.org/Search/Results?q=TMCO1'>TMCO1</a></td><td>TMCO1</td><td>8924</td><td>0.058</td><td>0.0748</td><td>No</td></tr><tr><td class='lessen'>47</td><td><a href='https://ensembl.org/Search/Results?q=KANK1'>KANK1</a></td><td>KANK1</td><td>9092</td><td>0.047</td><td>0.0680</td><td>No</td></tr><tr><td class='lessen'>48</td><td><a href='https://ensembl.org/Search/Results?q=VPS72'>VPS72</a></td><td>VPS72</td><td>9260</td><td>0.036</td><td>0.0611</td><td>No</td></tr><tr><td class='lessen'>49</td><td><a href='https://ensembl.org/Search/Results?q=GOLPH3'>GOLPH3</a></td><td>GOLPH3</td><td>9287</td><td>0.033</td><td>0.0605</td><td>No</td></tr><tr><td class='lessen'>50</td><td><a href='https://ensembl.org/Search/Results?q=HPS5'>HPS5</a></td><td>HPS5</td><td>9389</td><td>0.026</td><td>0.0564</td><td>No</td></tr><tr><td class='lessen'>51</td><td><a href='https://ensembl.org/Search/Results?q=KLF12'>KLF12</a></td><td>KLF12</td><td>10491</td><td>0.000</td><td>0.0065</td><td>No</td></tr><tr><td class='lessen'>52</td><td><a href='https://ensembl.org/Search/Results?q=GPRC5B'>GPRC5B</a></td><td>GPRC5B</td><td>13298</td><td>-0.009</td><td>-0.1204</td><td>No</td></tr><tr><td class='lessen'>53</td><td><a href='https://ensembl.org/Search/Results?q=PSD3'>PSD3</a></td><td>PSD3</td><td>13316</td><td>-0.011</td><td>-0.1209</td><td>No</td></tr><tr><td class='lessen'>54</td><td><a href='https://ensembl.org/Search/Results?q=ERI3'>ERI3</a></td><td>ERI3</td><td>13730</td><td>-0.041</td><td>-0.1389</td><td>No</td></tr><tr><td class='lessen'>55</td><td><a href='https://ensembl.org/Search/Results?q=RNMT'>RNMT</a></td><td>RNMT</td><td>13928</td><td>-0.055</td><td>-0.1469</td><td>No</td></tr><tr><td class='lessen'>56</td><td><a href='https://ensembl.org/Search/Results?q=ACSL1'>ACSL1</a></td><td>ACSL1</td><td>14132</td><td>-0.069</td><td>-0.1549</td><td>No</td></tr><tr><td class='lessen'>57</td><td><a href='https://ensembl.org/Search/Results?q=TBPL1'>TBPL1</a></td><td>TBPL1</td><td>14146</td><td>-0.071</td><td>-0.1543</td><td>No</td></tr><tr><td class='lessen'>58</td><td><a href='https://ensembl.org/Search/Results?q=ELOVL5'>ELOVL5</a></td><td>ELOVL5</td><td>14297</td><td>-0.082</td><td>-0.1597</td><td>No</td></tr><tr><td class='lessen'>59</td><td><a href='https://ensembl.org/Search/Results?q=IBTK'>IBTK</a></td><td>IBTK</td><td>14488</td><td>-0.094</td><td>-0.1667</td><td>No</td></tr><tr><td class='lessen'>60</td><td><a href='https://ensembl.org/Search/Results?q=TRPM3'>TRPM3</a></td><td>TRPM3</td><td>14892</td><td>-0.125</td><td>-0.1828</td><td>No</td></tr><tr><td class='lessen'>61</td><td><a href='https://ensembl.org/Search/Results?q=P2RY1'>P2RY1</a></td><td>P2RY1</td><td>14963</td><td>-0.130</td><td>-0.1837</td><td>No</td></tr><tr><td class='lessen'>62</td><td><a href='https://ensembl.org/Search/Results?q=CREG1'>CREG1</a></td><td>CREG1</td><td>15986</td><td>-0.233</td><td>-0.2260</td><td>No</td></tr><tr><td class='lessen'>63</td><td><a href='https://ensembl.org/Search/Results?q=TMEM123'>TMEM123</a></td><td>TMEM123</td><td>16015</td><td>-0.234</td><td>-0.2232</td><td>No</td></tr><tr><td class='lessen'>64</td><td><a href='https://ensembl.org/Search/Results?q=LRRFIP1'>LRRFIP1</a></td><td>LRRFIP1</td><td>16039</td><td>-0.236</td><td>-0.2202</td><td>No</td></tr><tr><td class='lessen'>65</td><td><a href='https://ensembl.org/Search/Results?q=HIP1'>HIP1</a></td><td>HIP1</td><td>16324</td><td>-0.271</td><td>-0.2284</td><td>No</td></tr><tr><td class='lessen'>66</td><td><a href='https://ensembl.org/Search/Results?q=SPATA6'>SPATA6</a></td><td>SPATA6</td><td>16435</td><td>-0.287</td><td>-0.2285</td><td>No</td></tr><tr><td class='lessen'>67</td><td><a href='https://ensembl.org/Search/Results?q=CACNB2'>CACNB2</a></td><td>CACNB2</td><td>16617</td><td>-0.315</td><td>-0.2313</td><td>No</td></tr><tr><td class='lessen'>68</td><td><a href='https://ensembl.org/Search/Results?q=UTP6'>UTP6</a></td><td>UTP6</td><td>16623</td><td>-0.316</td><td>-0.2261</td><td>No</td></tr><tr><td class='lessen'>69</td><td><a href='https://ensembl.org/Search/Results?q=LUZP1'>LUZP1</a></td><td>LUZP1</td><td>16922</td><td>-0.366</td><td>-0.2333</td><td>No</td></tr><tr><td class='lessen'>70</td><td><a href='https://ensembl.org/Search/Results?q=RAB11FIP2'>RAB11FIP2</a></td><td>RAB11FIP2</td><td>16988</td><td>-0.378</td><td>-0.2297</td><td>No</td></tr><tr><td class='lessen'>71</td><td><a href='https://ensembl.org/Search/Results?q=TARS'>TARS</a></td><td>TARS</td><td>17011</td><td>-0.383</td><td>-0.2241</td><td>No</td></tr><tr><td class='lessen'>72</td><td><a href='https://ensembl.org/Search/Results?q=GAS1'>GAS1</a></td><td>GAS1</td><td>17305</td><td>-0.440</td><td>-0.2298</td><td>No</td></tr><tr><td class='lessen'>73</td><td><a href='https://ensembl.org/Search/Results?q=FLRT1'>FLRT1</a></td><td>FLRT1</td><td>17402</td><td>-0.462</td><td>-0.2263</td><td>No</td></tr><tr><td class='lessen'>74</td><td><a href='https://ensembl.org/Search/Results?q=ATIC'>ATIC</a></td><td>ATIC</td><td>17448</td><td>-0.471</td><td>-0.2202</td><td>No</td></tr><tr><td class='lessen'>75</td><td><a href='https://ensembl.org/Search/Results?q=TMEM156'>TMEM156</a></td><td>TMEM156</td><td>17958</td><td>-0.599</td><td>-0.2330</td><td>No</td></tr><tr><td class='lessen'>76</td><td><a href='https://ensembl.org/Search/Results?q=CACNG1'>CACNG1</a></td><td>CACNG1</td><td>18424</td><td>-0.602</td><td>-0.2437</td><td>No</td></tr><tr><td class='lessen'>77</td><td><a href='https://ensembl.org/Search/Results?q=BCL2L1'>BCL2L1</a></td><td>BCL2L1</td><td>18952</td><td>-0.603</td><td>-0.2572</td><td>No</td></tr><tr><td class='lessen'>78</td><td><a href='https://ensembl.org/Search/Results?q=NSL1'>NSL1</a></td><td>NSL1</td><td>19317</td><td>-0.632</td><td>-0.2628</td><td>No</td></tr><tr><td class='lessen'>79</td><td><a href='https://ensembl.org/Search/Results?q=PTCD3'>PTCD3</a></td><td>PTCD3</td><td>19652</td><td>-0.688</td><td>-0.2661</td><td>No</td></tr><tr><td class='lessen'>80</td><td><a href='https://ensembl.org/Search/Results?q=ING4'>ING4</a></td><td>ING4</td><td>20296</td><td>-1.006</td><td>-0.2780</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>81</td><td><a href='https://ensembl.org/Search/Results?q=SLC7A1'>SLC7A1</a></td><td>SLC7A1</td><td>20353</td><td>-1.044</td><td>-0.2626</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>82</td><td><a href='https://ensembl.org/Search/Results?q=MYO1C'>MYO1C</a></td><td>MYO1C</td><td>20732</td><td>-1.333</td><td>-0.2568</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>83</td><td><a href='https://ensembl.org/Search/Results?q=CARD10'>CARD10</a></td><td>CARD10</td><td>20980</td><td>-1.591</td><td>-0.2407</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>84</td><td><a href='https://ensembl.org/Search/Results?q=EHD4'>EHD4</a></td><td>EHD4</td><td>20981</td><td>-1.592</td><td>-0.2134</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>85</td><td><a href='https://ensembl.org/Search/Results?q=RAI14'>RAI14</a></td><td>RAI14</td><td>21461</td><td>-2.310</td><td>-0.1954</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>86</td><td><a href='https://ensembl.org/Search/Results?q=FXYD5'>FXYD5</a></td><td>FXYD5</td><td>21552</td><td>-2.588</td><td>-0.1550</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>87</td><td><a href='https://ensembl.org/Search/Results?q=FHL2'>FHL2</a></td><td>FHL2</td><td>21662</td><td>-2.802</td><td>-0.1119</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>88</td><td><a href='https://ensembl.org/Search/Results?q=DPP6'>DPP6</a></td><td>DPP6</td><td>21694</td><td>-2.868</td><td>-0.0640</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>89</td><td><a href='https://ensembl.org/Search/Results?q=KLHDC8A'>KLHDC8A</a></td><td>KLHDC8A</td><td>22017</td><td>-5.000</td><td>0.0072</td><td bgcolor='#CCFFCC'>Yes</td></tr><caption class='table'>Table: GSEA details <a href='POU3F3_REGULON.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='POU3F3_REGULON' src='POU3F3_REGULON_382.png'><br><br><caption>Fig 2: POU3F3_REGULON    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_383.png'><br><br><caption>Fig 3: POU3F3_REGULON: Random ES distribution    <br> Gene set null distribution of ES for <b>POU3F3_REGULON</b></caption></div><br></body></html>