<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set WANG_CL_2017[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>ranaseq_carol_ns_sel_exprs.ranaseq_carol_ns_sel_phenotype.cls<br>#Fosl1_1_versus_Ctrl</td></tr><tr><td>Phenotype</td><td>ranaseq_carol_ns_sel_phenotype.cls#Fosl1_1_versus_Ctrl</td></tr><tr><td>Upregulated in class</td><td>Fosl1_1</td></tr><tr><td>GeneSet</td><td>WANG_CL_2017</td></tr><tr><td>Enrichment Score (ES)</td><td>0.48503786</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>1.3338069</td></tr><tr><td>Nominal p-value</td><td>0.06904232</td></tr><tr><td>FDR q-value</td><td>0.05356666</td></tr><tr><td>FWER p-Value</td><td>0.468</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_WANG_CL_2017' src='enplot_WANG_CL_2017_321.png'><br><br><caption>Fig 1: Enrichment plot: WANG_CL_2017    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=EYA2'>EYA2</a></td><td>EYA2</td><td>13</td><td>5.000</td><td>0.1717</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=ELOVL2'>ELOVL2</a></td><td>ELOVL2</td><td>760</td><td>1.806</td><td>0.2002</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=FGFR3'>FGFR3</a></td><td>FGFR3</td><td>800</td><td>1.743</td><td>0.2585</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=PAX6'>PAX6</a></td><td>PAX6</td><td>1043</td><td>1.427</td><td>0.2967</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=GATM'>GATM</a></td><td>GATM</td><td>1204</td><td>1.287</td><td>0.3338</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=ZFHX4'>ZFHX4</a></td><td>ZFHX4</td><td>1382</td><td>1.167</td><td>0.3660</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=PLCE1'>PLCE1</a></td><td>PLCE1</td><td>1675</td><td>1.019</td><td>0.3880</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=CDH4'>CDH4</a></td><td>CDH4</td><td>1768</td><td>0.972</td><td>0.4173</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=ACSBG1'>ACSBG1</a></td><td>ACSBG1</td><td>1879</td><td>0.919</td><td>0.4440</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=MLC1'>MLC1</a></td><td>MLC1</td><td>1922</td><td>0.899</td><td>0.4731</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=ARNTL'>ARNTL</a></td><td>ARNTL</td><td>2480</td><td>0.714</td><td>0.4725</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=SLC4A4'>SLC4A4</a></td><td>SLC4A4</td><td>2714</td><td>0.670</td><td>0.4850</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=CST3'>CST3</a></td><td>CST3</td><td>4259</td><td>0.580</td><td>0.4353</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=BBS1'>BBS1</a></td><td>BBS1</td><td>4746</td><td>0.463</td><td>0.4293</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=PHKB'>PHKB</a></td><td>PHKB</td><td>4780</td><td>0.458</td><td>0.4435</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=SOX9'>SOX9</a></td><td>SOX9</td><td>4879</td><td>0.441</td><td>0.4543</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=PPARGC1A'>PPARGC1A</a></td><td>PPARGC1A</td><td>5094</td><td>0.406</td><td>0.4586</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=SALL1'>SALL1</a></td><td>SALL1</td><td>5296</td><td>0.378</td><td>0.4626</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=ZHX3'>ZHX3</a></td><td>ZHX3</td><td>5322</td><td>0.374</td><td>0.4743</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=LHFP'>LHFP</a></td><td>LHFP</td><td>5665</td><td>0.327</td><td>0.4701</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=PTPRA'>PTPRA</a></td><td>PTPRA</td><td>5785</td><td>0.312</td><td>0.4755</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=NCOA1'>NCOA1</a></td><td>NCOA1</td><td>6089</td><td>0.277</td><td>0.4713</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=PLCG1'>PLCG1</a></td><td>PLCG1</td><td>6167</td><td>0.267</td><td>0.4771</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=VAV3'>VAV3</a></td><td>VAV3</td><td>7750</td><td>0.134</td><td>0.4102</td><td>No</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=SPRY2'>SPRY2</a></td><td>SPRY2</td><td>7766</td><td>0.133</td><td>0.4141</td><td>No</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=CTNND1'>CTNND1</a></td><td>CTNND1</td><td>8301</td><td>0.098</td><td>0.3934</td><td>No</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=USP8'>USP8</a></td><td>USP8</td><td>8642</td><td>0.076</td><td>0.3806</td><td>No</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=RBCK1'>RBCK1</a></td><td>RBCK1</td><td>9471</td><td>0.021</td><td>0.3439</td><td>No</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=DTNA'>DTNA</a></td><td>DTNA</td><td>9500</td><td>0.018</td><td>0.3433</td><td>No</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=RASGRP1'>RASGRP1</a></td><td>RASGRP1</td><td>11069</td><td>0.000</td><td>0.2725</td><td>No</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=SEPT11'>SEPT11</a></td><td>SEPT11</td><td>13122</td><td>-0.002</td><td>0.1798</td><td>No</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=TYK2'>TYK2</a></td><td>TYK2</td><td>13868</td><td>-0.051</td><td>0.1479</td><td>No</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=DENND2A'>DENND2A</a></td><td>DENND2A</td><td>13990</td><td>-0.060</td><td>0.1445</td><td>No</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=STXBP3'>STXBP3</a></td><td>STXBP3</td><td>14001</td><td>-0.060</td><td>0.1461</td><td>No</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=POLRMT'>POLRMT</a></td><td>POLRMT</td><td>14552</td><td>-0.100</td><td>0.1247</td><td>No</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=UPF1'>UPF1</a></td><td>UPF1</td><td>14728</td><td>-0.114</td><td>0.1207</td><td>No</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=NPEPL1'>NPEPL1</a></td><td>NPEPL1</td><td>14755</td><td>-0.116</td><td>0.1235</td><td>No</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=PNPLA6'>PNPLA6</a></td><td>PNPLA6</td><td>15749</td><td>-0.206</td><td>0.0858</td><td>No</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=TJP1'>TJP1</a></td><td>TJP1</td><td>15818</td><td>-0.214</td><td>0.0901</td><td>No</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=ABLIM1'>ABLIM1</a></td><td>ABLIM1</td><td>16460</td><td>-0.291</td><td>0.0711</td><td>No</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=BCKDHB'>BCKDHB</a></td><td>BCKDHB</td><td>16778</td><td>-0.344</td><td>0.0687</td><td>No</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=ACSL3'>ACSL3</a></td><td>ACSL3</td><td>17098</td><td>-0.401</td><td>0.0681</td><td>No</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=SLC20A2'>SLC20A2</a></td><td>SLC20A2</td><td>17549</td><td>-0.501</td><td>0.0650</td><td>No</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=SLC3A2'>SLC3A2</a></td><td>SLC3A2</td><td>17728</td><td>-0.559</td><td>0.0762</td><td>No</td></tr><tr><td class='lessen'>45</td><td><a href='https://ensembl.org/Search/Results?q=GRIK1'>GRIK1</a></td><td>GRIK1</td><td>17878</td><td>-0.599</td><td>0.0901</td><td>No</td></tr><tr><td class='lessen'>46</td><td><a href='https://ensembl.org/Search/Results?q=MYO5C'>MYO5C</a></td><td>MYO5C</td><td>21742</td><td>-3.020</td><td>0.0196</td><td>No</td></tr><caption class='table'>Table: GSEA details <a href='WANG_CL_2017.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='WANG_CL_2017' src='WANG_CL_2017_322.png'><br><br><caption>Fig 2: WANG_CL_2017    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_323.png'><br><br><caption>Fig 3: WANG_CL_2017: Random ES distribution    <br> Gene set null distribution of ES for <b>WANG_CL_2017</b></caption></div><br></body></html>