<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/1999/REC-html401-19991224/loose.dtd"> <html><head><title>Details for gene set WANG_MES_2017[GSEA]</title><link href='xtools.css' rel='stylesheet'><link href='http://www.gsea-msigdb.org/gsea/images/icon_16x16.png' rel='shortcut icon'></head><body><div class='keyValTable'><table cols='2' border='0'><th class='keyValTable'></th><th class='keyValTable'></th><tr><td>Dataset</td><td>ranaseq_carol_ns_sel_exprs.ranaseq_carol_ns_sel_phenotype.cls<br>#Fosl1_1_versus_Ctrl</td></tr><tr><td>Phenotype</td><td>ranaseq_carol_ns_sel_phenotype.cls#Fosl1_1_versus_Ctrl</td></tr><tr><td>Upregulated in class</td><td>Ctrl</td></tr><tr><td>GeneSet</td><td>WANG_MES_2017</td></tr><tr><td>Enrichment Score (ES)</td><td>-0.71134084</td></tr><tr><td>Normalized Enrichment Score (NES)</td><td>-1.8912324</td></tr><tr><td>Nominal p-value</td><td>0.0</td></tr><tr><td>FDR q-value</td><td>0.0</td></tr><tr><td>FWER p-Value</td><td>0.0</td></tr><caption class='table'>Table: GSEA Results Summary</caption></table></div><br><div class='image'><img name='enplot_WANG_MES_2017' src='enplot_WANG_MES_2017_351.png'><br><br><caption>Fig 1: Enrichment plot: WANG_MES_2017    <br> Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List</caption></div><br><div class='richTable'><table cols='7' border='1'><th class='richTable'></th><th class='richTable'>SYMBOL</th><th class='richTable'>TITLE</th><th class='richTable'>RANK IN GENE LIST</th><th class='richTable'>RANK METRIC SCORE</th><th class='richTable'>RUNNING ES</th><th class='richTable'>CORE ENRICHMENT</th><tr><td class='lessen'>1</td><td><a href='https://ensembl.org/Search/Results?q=LOX'>LOX</a></td><td>LOX</td><td>30</td><td>5.000</td><td>0.0799</td><td>No</td></tr><tr><td class='lessen'>2</td><td><a href='https://ensembl.org/Search/Results?q=BACE2'>BACE2</a></td><td>BACE2</td><td>1714</td><td>0.998</td><td>0.0200</td><td>No</td></tr><tr><td class='lessen'>3</td><td><a href='https://ensembl.org/Search/Results?q=COL1A1'>COL1A1</a></td><td>COL1A1</td><td>3080</td><td>0.631</td><td>-0.0314</td><td>No</td></tr><tr><td class='lessen'>4</td><td><a href='https://ensembl.org/Search/Results?q=COL15A1'>COL15A1</a></td><td>COL15A1</td><td>3091</td><td>0.631</td><td>-0.0216</td><td>No</td></tr><tr><td class='lessen'>5</td><td><a href='https://ensembl.org/Search/Results?q=COL1A2'>COL1A2</a></td><td>COL1A2</td><td>3781</td><td>0.602</td><td>-0.0429</td><td>No</td></tr><tr><td class='lessen'>6</td><td><a href='https://ensembl.org/Search/Results?q=TNFAIP8'>TNFAIP8</a></td><td>TNFAIP8</td><td>7743</td><td>0.135</td><td>-0.2197</td><td>No</td></tr><tr><td class='lessen'>7</td><td><a href='https://ensembl.org/Search/Results?q=CYP1B1'>CYP1B1</a></td><td>CYP1B1</td><td>8111</td><td>0.111</td><td>-0.2345</td><td>No</td></tr><tr><td class='lessen'>8</td><td><a href='https://ensembl.org/Search/Results?q=SPAG4'>SPAG4</a></td><td>SPAG4</td><td>8947</td><td>0.056</td><td>-0.2713</td><td>No</td></tr><tr><td class='lessen'>9</td><td><a href='https://ensembl.org/Search/Results?q=GLIPR1'>GLIPR1</a></td><td>GLIPR1</td><td>10239</td><td>0.000</td><td>-0.3297</td><td>No</td></tr><tr><td class='lessen'>10</td><td><a href='https://ensembl.org/Search/Results?q=IL7R'>IL7R</a></td><td>IL7R</td><td>10774</td><td>0.000</td><td>-0.3538</td><td>No</td></tr><tr><td class='lessen'>11</td><td><a href='https://ensembl.org/Search/Results?q=IL6'>IL6</a></td><td>IL6</td><td>11016</td><td>0.000</td><td>-0.3647</td><td>No</td></tr><tr><td class='lessen'>12</td><td><a href='https://ensembl.org/Search/Results?q=CDCP1'>CDCP1</a></td><td>CDCP1</td><td>11299</td><td>0.000</td><td>-0.3774</td><td>No</td></tr><tr><td class='lessen'>13</td><td><a href='https://ensembl.org/Search/Results?q=LUM'>LUM</a></td><td>LUM</td><td>11318</td><td>0.000</td><td>-0.3782</td><td>No</td></tr><tr><td class='lessen'>14</td><td><a href='https://ensembl.org/Search/Results?q=ANPEP'>ANPEP</a></td><td>ANPEP</td><td>11375</td><td>0.000</td><td>-0.3808</td><td>No</td></tr><tr><td class='lessen'>15</td><td><a href='https://ensembl.org/Search/Results?q=RAB27A'>RAB27A</a></td><td>RAB27A</td><td>13040</td><td>-0.001</td><td>-0.4559</td><td>No</td></tr><tr><td class='lessen'>16</td><td><a href='https://ensembl.org/Search/Results?q=PRSS23'>PRSS23</a></td><td>PRSS23</td><td>14005</td><td>-0.061</td><td>-0.4985</td><td>No</td></tr><tr><td class='lessen'>17</td><td><a href='https://ensembl.org/Search/Results?q=CTSB'>CTSB</a></td><td>CTSB</td><td>14332</td><td>-0.083</td><td>-0.5119</td><td>No</td></tr><tr><td class='lessen'>18</td><td><a href='https://ensembl.org/Search/Results?q=CTSC'>CTSC</a></td><td>CTSC</td><td>14598</td><td>-0.104</td><td>-0.5222</td><td>No</td></tr><tr><td class='lessen'>19</td><td><a href='https://ensembl.org/Search/Results?q=RGS2'>RGS2</a></td><td>RGS2</td><td>16379</td><td>-0.280</td><td>-0.5981</td><td>No</td></tr><tr><td class='lessen'>20</td><td><a href='https://ensembl.org/Search/Results?q=ITGB1'>ITGB1</a></td><td>ITGB1</td><td>17091</td><td>-0.399</td><td>-0.6237</td><td>No</td></tr><tr><td class='lessen'>21</td><td><a href='https://ensembl.org/Search/Results?q=SYNGR2'>SYNGR2</a></td><td>SYNGR2</td><td>17814</td><td>-0.588</td><td>-0.6468</td><td>No</td></tr><tr><td class='lessen'>22</td><td><a href='https://ensembl.org/Search/Results?q=VDR'>VDR</a></td><td>VDR</td><td>18436</td><td>-0.602</td><td>-0.6650</td><td>No</td></tr><tr><td class='lessen'>23</td><td><a href='https://ensembl.org/Search/Results?q=CD72'>CD72</a></td><td>CD72</td><td>19111</td><td>-0.630</td><td>-0.6853</td><td>No</td></tr><tr><td class='lessen'>24</td><td><a href='https://ensembl.org/Search/Results?q=ARPC1B'>ARPC1B</a></td><td>ARPC1B</td><td>19689</td><td>-0.703</td><td>-0.6999</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>25</td><td><a href='https://ensembl.org/Search/Results?q=SDC1'>SDC1</a></td><td>SDC1</td><td>19916</td><td>-0.776</td><td>-0.6975</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>26</td><td><a href='https://ensembl.org/Search/Results?q=CNN2'>CNN2</a></td><td>CNN2</td><td>20029</td><td>-0.843</td><td>-0.6889</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>27</td><td><a href='https://ensembl.org/Search/Results?q=COL5A1'>COL5A1</a></td><td>COL5A1</td><td>20235</td><td>-0.973</td><td>-0.6824</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>28</td><td><a href='https://ensembl.org/Search/Results?q=THBS1'>THBS1</a></td><td>THBS1</td><td>20398</td><td>-1.082</td><td>-0.6721</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>29</td><td><a href='https://ensembl.org/Search/Results?q=LY96'>LY96</a></td><td>LY96</td><td>20565</td><td>-1.199</td><td>-0.6601</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>30</td><td><a href='https://ensembl.org/Search/Results?q=COL3A1'>COL3A1</a></td><td>COL3A1</td><td>20641</td><td>-1.253</td><td>-0.6432</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>31</td><td><a href='https://ensembl.org/Search/Results?q=BCL3'>BCL3</a></td><td>BCL3</td><td>20841</td><td>-1.433</td><td>-0.6289</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>32</td><td><a href='https://ensembl.org/Search/Results?q=IER3'>IER3</a></td><td>IER3</td><td>20879</td><td>-1.462</td><td>-0.6068</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>33</td><td><a href='https://ensembl.org/Search/Results?q=NDRG1'>NDRG1</a></td><td>NDRG1</td><td>21010</td><td>-1.628</td><td>-0.5862</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>34</td><td><a href='https://ensembl.org/Search/Results?q=RARRES1'>RARRES1</a></td><td>RARRES1</td><td>21226</td><td>-1.909</td><td>-0.5649</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>35</td><td><a href='https://ensembl.org/Search/Results?q=PTGS2'>PTGS2</a></td><td>PTGS2</td><td>21243</td><td>-1.932</td><td>-0.5343</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>36</td><td><a href='https://ensembl.org/Search/Results?q=GPRC5A'>GPRC5A</a></td><td>GPRC5A</td><td>21338</td><td>-2.072</td><td>-0.5048</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>37</td><td><a href='https://ensembl.org/Search/Results?q=NNMT'>NNMT</a></td><td>NNMT</td><td>21524</td><td>-2.484</td><td>-0.4728</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>38</td><td><a href='https://ensembl.org/Search/Results?q=S100A11'>S100A11</a></td><td>S100A11</td><td>21526</td><td>-2.486</td><td>-0.4325</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>39</td><td><a href='https://ensembl.org/Search/Results?q=RUNX1'>RUNX1</a></td><td>RUNX1</td><td>21549</td><td>-2.581</td><td>-0.3916</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>40</td><td><a href='https://ensembl.org/Search/Results?q=CAV1'>CAV1</a></td><td>CAV1</td><td>21642</td><td>-2.729</td><td>-0.3514</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>41</td><td><a href='https://ensembl.org/Search/Results?q=ACPP'>ACPP</a></td><td>ACPP</td><td>21734</td><td>-2.991</td><td>-0.3069</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>42</td><td><a href='https://ensembl.org/Search/Results?q=TGFBI'>TGFBI</a></td><td>TGFBI</td><td>21757</td><td>-3.092</td><td>-0.2577</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>43</td><td><a href='https://ensembl.org/Search/Results?q=P4HA2'>P4HA2</a></td><td>P4HA2</td><td>21767</td><td>-3.184</td><td>-0.2064</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>44</td><td><a href='https://ensembl.org/Search/Results?q=SLPI'>SLPI</a></td><td>SLPI</td><td>21831</td><td>-4.029</td><td>-0.1438</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>45</td><td><a href='https://ensembl.org/Search/Results?q=PLAUR'>PLAUR</a></td><td>PLAUR</td><td>21880</td><td>-4.804</td><td>-0.0679</td><td bgcolor='#CCFFCC'>Yes</td></tr><tr><td class='lessen'>46</td><td><a href='https://ensembl.org/Search/Results?q=BNC2'>BNC2</a></td><td>BNC2</td><td>21985</td><td>-5.000</td><td>0.0086</td><td bgcolor='#CCFFCC'>Yes</td></tr><caption class='table'>Table: GSEA details <a href='WANG_MES_2017.tsv'>[plain text format]</a></caption></table></div><br><div class='image'><img name='WANG_MES_2017' src='WANG_MES_2017_352.png'><br><br><caption>Fig 2: WANG_MES_2017    <br> Blue-Pink O' Gram in the Space of the Analyzed GeneSet</caption></div><br><div class='image'><img name='gset_rnd_es_dist' src='gset_rnd_es_dist_353.png'><br><br><caption>Fig 3: WANG_MES_2017: Random ES distribution    <br> Gene set null distribution of ES for <b>WANG_MES_2017</b></caption></div><br></body></html>